A trypsin-like protease with apparent dual function in early Lepeophtheirus salmonis (Krøyer) developmentSpringer Science and Business Media LLC - Tập 10 - Trang 1-11 - 2009
Rasmus Skern-Mauritzen, Petter Frost, Sussie Dalvin, Bjørn Olav Kvamme, Ingunn Sommerset, Frank Nilsen
Trypsin-like serine proteases are involved in a large number of processes including digestive degradation, regulation of developmental processes, yolk degradation and yolk degradome activation. Trypsin like peptidases considered to be involved in digestion have been characterized in Lepeophtheirus salmonis. During these studies a trypsin-like peptidase which differed in a number of traits were ide...... hiện toàn bộ
Characterization, phylogeny, alternative splicing and expression of Sox30 geneSpringer Science and Business Media LLC - Tập 11 - Trang 1-11 - 2010
Fei Han, Zhijian Wang, Fengrui Wu, Zhihao Liu, Baofeng Huang, Deshou Wang
Members of the Sox gene family isolated from both vertebrates and invertebrates have been proved to participate in a wide variety of developmental processes, including sex determination and differentiation. Among these members, Sox30 had been considered to exist only in mammals since its discovery, and its exact function remains unclear. Sox30 cDNA was cloned from the Nile tilapia by RT-PCR and RA...... hiện toàn bộ
Expression of yeast lipid phosphatase Sac1p is regulated by phosphatidylinositol-4-phosphateSpringer Science and Business Media LLC - Tập 9 - Trang 1-10 - 2008
Andreas Knödler, Gerlinde Konrad, Peter Mayinger
Phosphoinositides play a central role in regulating processes at intracellular membranes. In yeast, a large number of phospholipid biosynthetic enzymes use a common mechanism for transcriptional regulation. Yet, how the expression of genes encoding lipid kinases and phosphatases is regulated remains unknown. Here we show that the expression of lipid phosphatase Sac1p in the yeast Saccharomyces cer...... hiện toàn bộ
Hfq stimulates the activity of the CCA-adding enzymeSpringer Science and Business Media LLC - Tập 8 - Trang 1-7 - 2007
Marion Scheibe, Sonja Bonin, Eliane Hajnsdorf, Heike Betat, Mario Mörl
The bacterial Sm-like protein Hfq is known as an important regulator involved in many reactions of RNA metabolism. A prominent function of Hfq is the stimulation of RNA polyadenylation catalyzed by E. coli poly(A) polymerase I (PAP). As a member of the nucleotidyltransferase superfamily, this enzyme shares a high sequence similarity with an other representative of this family, the tRNA nucleotidyl...... hiện toàn bộ
Chicken ovalbumin upstream promoter transcription factor II regulates uncoupling protein 3 gene transcription in Phodopus sungorusSpringer Science and Business Media LLC - Tập 8 - Trang 1-15 - 2007
Tobias Fromme, Kathrin Reichwald, Matthias Platzer, Xing-Sheng Li, Martin Klingenspor
Ucp3 is an integral protein of the inner mitochondrial membrane with a role in lipid metabolism preventing deleterious effects of fatty acids in states of high lipid oxidation. Ucp3 is expressed in brown adipose tissue and skeletal muscle and controlled by a transcription factor complex including PPARalpha, MyoD and the histone acetyltransferase p300. Several studies have demonstrated interaction ...... hiện toàn bộ
Quantitative polymerase chain reaction analysis by deconvolution of internal standardSpringer Science and Business Media LLC - - 2010
Yasuko Hirakawa, Rheem D. Medh, Stan Metzenberg
Abstract
Background
Quantitative Polymerase Chain Reaction (qPCR) is a collection of methods for estimating the number of copies of a specific DNA template in a sample, but one that is not universally accepted because it can lead to highly inaccurate (albeit precise) results. The fundamental prob...... hiện toàn bộ
Exploring cellular memory molecules marking competent and active transcriptionsSpringer Science and Business Media LLC - - 2007
Li X, Guangming Zhou, Wei Song, Xuesong Wu, Gong‐Hong Wei, Dejun Hao, Xiang Lv, De-Pei Liu, Chih‐Chuan Liang
Abstract
Background
Development in higher eukaryotes involves programmed gene expression. Cell type-specific gene expression is established during this process and is inherited in succeeding cell cycles. Higher eukaryotes have evolved elegant mechanisms by which committed gene-expression states a...... hiện toàn bộ
Regulation of CEACAM1 transcription in human breast epithelial cellsSpringer Science and Business Media LLC - Tập 11 - Trang 1-14 - 2010
Marieta Gencheva, Charng-Jui Chen, Tung Nguyen, John E Shively
Carcinoembryonic antigen cell adhesion molecule 1 (CEACAM1) is a transmembrane protein with multiple functions in different cell types. CEACAM1 expression is frequently mis-regulated in cancer, with down-regulation reported in several tumors of epithelial origin and de novo expression of CEACAM1 in lung cancer and malignant melanoma. In this report we analyzed the regulation of CEACAM1 expression ...... hiện toàn bộ
The TPR-containing domain within Est1 homologs exhibits species-specific roles in telomerase interaction and telomere length homeostasisSpringer Science and Business Media LLC - Tập 12 - Trang 1-15 - 2011
David CF Sealey, Aleksandar D Kostic, Catherine LeBel, Fiona Pryde, Lea Harrington
The first telomerase-associated protein (Est1) was isolated in yeast due to its essential role in telomere maintenance. The human counterparts EST1A, EST1B, and EST1C perform diverse functions in nonsense-mediated mRNA decay (NMD), telomere length homeostasis, and telomere transcription. Although Est1 and EST1A/B interact with the catalytic subunit of yeast and human telomerase (Est2 and TERT, res...... hiện toàn bộ