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A trypsin-like protease with apparent dual function in early Lepeophtheirus salmonis (Krøyer) development
Springer Science and Business Media LLC - Tập 10 - Trang 1-11 - 2009
Rasmus Skern-Mauritzen, Petter Frost, Sussie Dalvin, Bjørn Olav Kvamme, Ingunn Sommerset, Frank Nilsen
Trypsin-like serine proteases are involved in a large number of processes including digestive degradation, regulation of developmental processes, yolk degradation and yolk degradome activation. Trypsin like peptidases considered to be involved in digestion have been characterized in Lepeophtheirus salmonis. During these studies a trypsin-like peptidase which differed in a number of traits were ide... hiện toàn bộ
Characterization, phylogeny, alternative splicing and expression of Sox30 gene
Springer Science and Business Media LLC - Tập 11 - Trang 1-11 - 2010
Fei Han, Zhijian Wang, Fengrui Wu, Zhihao Liu, Baofeng Huang, Deshou Wang
Members of the Sox gene family isolated from both vertebrates and invertebrates have been proved to participate in a wide variety of developmental processes, including sex determination and differentiation. Among these members, Sox30 had been considered to exist only in mammals since its discovery, and its exact function remains unclear. Sox30 cDNA was cloned from the Nile tilapia by RT-PCR and RA... hiện toàn bộ
Expression of yeast lipid phosphatase Sac1p is regulated by phosphatidylinositol-4-phosphate
Springer Science and Business Media LLC - Tập 9 - Trang 1-10 - 2008
Andreas Knödler, Gerlinde Konrad, Peter Mayinger
Phosphoinositides play a central role in regulating processes at intracellular membranes. In yeast, a large number of phospholipid biosynthetic enzymes use a common mechanism for transcriptional regulation. Yet, how the expression of genes encoding lipid kinases and phosphatases is regulated remains unknown. Here we show that the expression of lipid phosphatase Sac1p in the yeast Saccharomyces cer... hiện toàn bộ
Hormonal and nutritional regulation of alternative CD36 transcripts in rat liver – a role for growth hormone in alternative exon usage
Springer Science and Business Media LLC - - 2007
Louisa Cheung, Malin Andersen, Catharina Gustavsson, Jacob Odeberg, Leandro Fernández-Pérez, Gunnar Norstedt, Petra Tollet-Egnell
An optimized rapid bisulfite conversion method with high recovery of cell-free DNA
Springer Science and Business Media LLC - Tập 18 Số 1 - 2017
Shaohua Yi, Fei Long, Juanbo Cheng, Daixin Huang
Flexible promoter architecture requirements for coactivator recruitment
Springer Science and Business Media LLC - Tập 7 - Trang 1-18 - 2006
Derek Y Chiang, David A Nix, Ryan K Shultzaberger, Audrey P Gasch, Michael B Eisen
The spatial organization of transcription factor binding sites in regulatory DNA, and the composition of intersite sequences, influences the assembly of the multiprotein complexes that regulate RNA polymerase recruitment and thereby affects transcription. We have developed a genetic approach to investigate how reporter gene transcription is affected by varying the spacing between transcription fac... hiện toàn bộ
TRPC1 transcript variants, inefficient nonsense-mediated decay and low up-frameshift-1 in vascular smooth muscle cells
Springer Science and Business Media LLC - Tập 12 - Trang 1-10 - 2011
Alexandra M Dedman, Yasser Majeed, Sarka Tumova, Fanning Zeng, Bhaskar Kumar, Christopher Munsch, Alan N Bateson, Jürgen Wittmann, Hans-Martin Jäck, Karen E Porter, David J Beech
Transient Receptor Potential Canonical 1 (TRPC1) is a widely-expressed mammalian cationic channel with functional effects that include stimulation of cardiovascular remodelling. The initial aim of this study was to investigate variation in TRPC1-encoding gene transcripts. Extensive TRPC1 transcript alternative splicing was observed, with exons 2, 3 and 5-9 frequently omitted, leading to variants c... hiện toàn bộ
Regulation of PURA gene transcription by three promoters generating distinctly spliced 5-prime leaders: a novel means of fine control over tissue specificity and viral signals
Springer Science and Business Media LLC - Tập 11 - Trang 1-15 - 2010
Margaret J Wortman, Laura K Hanson, Luis Martínez-Sobrido, Ann E Campbell, Jonas A Nance, Adolfo García-Sastre, Edward M Johnson
Purα is an evolutionarily conserved cellular protein participating in processes of DNA replication, transcription, and RNA transport; all involving binding to nucleic acids and altering conformation and physical positioning. The distinct but related roles of Purα suggest a need for expression regulated differently depending on intracellular and external signals. Here we report that human PURA (hPU... hiện toàn bộ
Hfq stimulates the activity of the CCA-adding enzyme
Springer Science and Business Media LLC - Tập 8 - Trang 1-7 - 2007
Marion Scheibe, Sonja Bonin, Eliane Hajnsdorf, Heike Betat, Mario Mörl
The bacterial Sm-like protein Hfq is known as an important regulator involved in many reactions of RNA metabolism. A prominent function of Hfq is the stimulation of RNA polyadenylation catalyzed by E. coli poly(A) polymerase I (PAP). As a member of the nucleotidyltransferase superfamily, this enzyme shares a high sequence similarity with an other representative of this family, the tRNA nucleotidyl... hiện toàn bộ
Prediction and preliminary validation of oncogene regulation by miRNAs
Springer Science and Business Media LLC - Tập 8 - Trang 1-14 - 2007
Edyta Koscianska, Vesselin Baev, Konstantinia Skreka, Katerina Oikonomaki, Ventsislav Rusinov, Martin Tabler, Kriton Kalantidis
MicroRNAs (miRNAs) are one of the most abundant groups of regulatory genes in multicellular organisms, playing important roles in many fundamental cellular processes. More than four hundred miRNAs have been identified in humans and the deregulation of miRNA expression has been also shown in many cancers. Despite the postulated involvement of miRNAs in tumourigenesis, there are only a few examples ... hiện toàn bộ
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