Primary Immunodeficiency in Iran: First Report of the National Registry of PID in Children and AdultsSpringer Science and Business Media LLC - Tập 22 - Trang 375-380 - 2002
Asghar Aghamohammadi, Mosafa Moein, Abolhasan Farhoudi, Zahra Pourpak, Nima Rezaei, Kamran Abolmaali, Masoud Movahedi, Mohammad Gharagozlou, Bahram Mir Saeid Ghazi, Maryam Mahmoudi, Davoud Mansouri, Saba Arshi, Naser Javaher Trash, Hedayatallah Akbari, Roya Sherkat, Reza Farid Hosayni, Ahmad Hashemzadeh, Iraj Mohammadzadeh, Reza Amin, Sara Kashef, Abdalvahab Alborzi, Abdallah Karimi, Hosaynali Khazaei
Epidemiological studies have shown wide geographical and racial variation in the prevalence and patterns of immunodeficiency disorders. To determine the frequency of primary immunodeficiencies (PID) in Iran, the Iranian Primary Immunodeficiency Registry (IPIDR) was organized in 1999. We extracted the patient’s data, by using a uniform questionnaire from their hospital records. The diagnosis of pat...... hiện toàn bộ
AnnouncementsSpringer Science and Business Media LLC - Tập 13 - Trang 371-372 - 1993
Spontaneous production of bone-resorbing lymphokines by B cells in patients with systemic lupus erythematosusSpringer Science and Business Media LLC - Tập 9 - Trang 415-420 - 1989
Yoshiya Tanaka, Kenichi Watanabe, Masahito Suzuki, Kazuyoshi Saito, Susumu Oda, Hidero Suzuki, Sumiya Eto, Uki Yamashita
The culture supernatant of B cells from patients with active systemic lupus erythematosus (SLE) who had never been treated with corticosteroids had bone-resorbing activity (BRA) which stimulated the45Ca release from prelabeled murine fetal bones. Then we studied the characteristics and the relationship of this BRA with several lymphokines previously reported. The BRA was eluted as three peaks at a...... hiện toàn bộ
Case Series: Convalescent Plasma Therapy for Patients with COVID-19 and Primary Antibody DeficiencySpringer Science and Business Media LLC - Tập 42 - Trang 253-265 - 2021
Julia Lang-Meli, Jonas Fuchs, Philipp Mathé, Hsi-en Ho, Lisa Kern, Lena Jaki, Giuseppe Rusignuolo, Susanne Mertins, Vivien Somogyi, Christoph Neumann-Haefelin, Frederik Trinkmann, Michael Müller, Robert Thimme, Markus Umhau, Isabella Quinti, Dirk Wagner, Marcus Panning, Charlotte Cunningham-Rundles, Katharina Laubner, Klaus Warnatz
Patients with primary antibody deficiency are at risk for severe and in many cases for prolonged COVID-19. Convalescent plasma treatment of immunocompromised individuals could be an option especially in countries with limited access to monoclonal antibody therapies. While studies in immunocompetent COVID19 patients have demonstrated only a limited benefit, evidence for the safety, timing, and effe...... hiện toàn bộ
Correction to: The Seven STAT3‑Related Hyper‑IgE SyndromesSpringer Science and Business Media LLC - Tập 41 Số 6 - Trang 1390-1390 - 2021
Fadil, Ilham, Ben‑Ali, Meriem, Jeddane, Leila, Barbouche, Mohamed‑Ridha, Bousfiha, Ahmed Aziz
A correction to this paper has been published: https://doi.org/10.1007/s10875-021-01058-8
Genetic Mosaicism as a Cause of Inborn Errors of ImmunitySpringer Science and Business Media LLC - Tập 41 - Trang 718-728 - 2021
Jahnavi Aluri, Megan A. Cooper
Inborn errors of immunity (IEIs) are a heterogeneous group of disorders due to genetic defects in the immune response that have a broad clinical spectrum. Diagnosis of the precise genetic cause of IEI has led to improved care and treatment of patients; however, genetic diagnosis using standard approaches is only successful in ~40% of patients and is particularly challenging in “sporadic” cases wit...... hiện toàn bộ
IL-10 suppresses cell surface CD23/FcεRII expression, not by enhancing soluble CD23 release, but by reducing CD23 mRNA expression in human monocytesSpringer Science and Business Media LLC - Tập 16 - Trang 326-333 - 1996
Akio Morinobu, Shunichi Kumagai, Hidetoshi Yanagida, Hiroyuki Ota, Hiroshi Ishida, Minoru Matsui, Junji Yodoi, Kazuwa Nakao
To examine a possible involvement of interleukin-10 (IL-10) in CD23/FcεRII expression in human monocytes, effects of IL-10 on the cell surface CD23 expression, soluble CD23 (sCD23) release, and CD23 type b mRNA expression were investigated. IL-10 suppressed IL-4-induced surface CD23 expression on monocytes in a dose-dependent manner, and this effect was completely neutralized by anti-IL-10 antibod...... hiện toàn bộ
Foxp3+ Regulatory T Cells, Th17 Effector Cells, and Cytokine Environment in Inflammatory Bowel DiseaseSpringer Science and Business Media LLC - Tập 30 - Trang 80-89 - 2009
Nicola Eastaff-Leung, Nicholas Mabarrack, Angela Barbour, Adrian Cummins, Simon Barry
Inflammatory bowel disease (IBD) is thought to result from an aberrant immune response. Inflammation in IBD may be caused by the loss of homeostasis between CD4+ CD25high Foxp3+ regulatory cells (T
reg) and proinflammatory Th17 cells. The aim of this study was to investigate T
reg and Th17 cells in the peripheral blood and intestinal mucosa of ...... hiện toàn bộ