Active surveillance eligibility of MRI-positive patients with grade group 2 prostate cancer: a pathological studySpringer Science and Business Media LLC - Tập 38 - Trang 1735-1740 - 2019
Guillaume Ploussard, Jean-Baptiste Beauval, Marine Lesourd, Cécile Manceau, Christophe Almeras, Richard Aziza, Jean-Romain Gautier, Guillaume Loison, Daniel Portalez, Ambroise Salin, Christophe Tollon, Michel Soulié, Bernard Malavaud, Mathieu Roumiguié
To assess the final pathology risk in MRI-positive grade group (GG) 2 prostate cancer (PCa) patients undergoing targeted (TB) and systematic (SB) biopsies, and thereby, the possibility of active surveillance (AS) in this population. We included 242 consecutive men diagnosed with GG2 PCa by a combination of SB and software-based fusion TB undergoing a radical prostatectomy (RP). The primary endpoin...... hiện toàn bộ
A randomized controlled trial evaluating sildenafil citrate in relieving ureteral stent-related symptomsSpringer Science and Business Media LLC - Tập 36 - Trang 1877-1881 - 2018
Mohamed Tharwat, Mohamed M. Elsaadany, Ahmed M. Lashin, Ahmed R. EL-Nahas
To evaluate the role of sildenafil in relieving ureteral stent symptoms. A randomized controlled trial was conducted between March 2014 and November 2016. It included adult men who underwent unilateral ureteric stent after ureteroscopy. Patients who were taking PDE5-Is, alpha-blockers or anticholinergics, had contraindication to sildenafil or developed postoperative complications were not included...... hiện toàn bộ
Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC)Springer Science and Business Media LLC - Tập 35 - Trang 379-387 - 2016
Francesco Soria, Shahrokh F. Shariat, Seth P. Lerner, Hans-Martin Fritsche, Michael Rink, Wassim Kassouf, Philippe E. Spiess, Yair Lotan, Dingwei Ye, Mario I. Fernández, Eiji Kikuchi, Daher C. Chade, Marko Babjuk, Arthur P. Grollman, George N. Thalmann
Upper-tract urothelial carcinoma (UTUC) is a relatively uncommon disease with limited available evidence on specific topics. The purpose of this article was to review the previous literature to summarize the current knowledge about UTUC epidemiology, diagnosis, preoperative evaluation and prognostic assessment.
Using MEDLINE, a non-systematic review was performed including articles between Januar...... hiện toàn bộ
Low prevalence of HPV detection and genotyping in non-muscle invasive bladder cancer using single-step PCR followed by reverse line blotSpringer Science and Business Media LLC - Tập 33 - Trang 2145-2151 - 2015
Renate Pichler, Wegene Borena, Georg Schäfer, Claudia Manzl, Zoran Culig, Sebastian List, Sabrina Neururer, Dorothee Von Laer, Isabel Heidegger, Helmut Klocker, Wolfgang Horninger, Hannes Steiner, Andrea Brunner
To clarify the role of human papillomavirus (HPV) in non-muscle invasive bladder cancer, HPV-DNA was scrutinized in formalin-fixed, paraffin-embedded (FFPE) bladder cancer tissue using single-step PCR (HPV L1) for HPV detection, followed by reverse line blot (RLB) for genotyping. A total of 186 patients who underwent transurethral resection of the bladder due to primary, non-muscle invasive bladde...... hiện toàn bộ
Protective effect of trapidil on long-term histologic damage in a rat model of testicular ischemia-reperfusion injurySpringer Science and Business Media LLC - Tập 27 - Trang 117-122 - 2008
Murat Bozlu, Deniz Acar, Selahittin Cayan, Savas Aktas, Ahmet Tunckiran
Trapidil is an antianginal compound with a broad spectrum of pharmacological activities. In recent years, it has been used successfully to decrease ischemia-reperfusion injury in several organ systems. We evaluated the effect of trapidil on the long-term histologic damage in testicular ischemia-reperfusion injury. Adult male Wistar rats were divided into three groups of six rats each. One group un...... hiện toàn bộ
Mediators of the female sexual response: pharmacotherapeutic implicationsSpringer Science and Business Media LLC - Tập 20 - Trang 101-105 - 2002
Arthur L. Burnett, Michael C. Truss
A basic understanding of the mediators and related mechanisms involved in the genital physiology of the female sexual response, and, in particular, the physiology of arousal, is paramount for the clinical practitioner whose medical knowledge and practice pertain to female sexual dysfunction. Familiarity with established and evolving scientific principles relating to female genital physiology offe...... hiện toàn bộ