The diagnosis of primary insomnia and treatment alternativesSpringer Science and Business Media LLC - Tập 26 - Trang 298-306 - 2000
Michael L. Perlis, Shawn D. Youngstedt
This review provides information about the diagnosis and treatment of primary insomnia. Several treatment strategies are reviewed including the use of hypnotics, naturopathic remedies and behavioral interventions. We suggest that nonpharmacologic interventions are likely to be the most safe and effective.
Role of impaired insulin secretion and insulin resistance in the pathogenesis of type 2 diabetes mellitusSpringer Science and Business Media LLC - Tập 31 - Trang 106-112 - 2005
Ervin Szoke, John E. Gerich
Type 2 diabetes mellitus (T2DM) is a heterogenous disorder caused by a combination of genetic and acquired abnormalities that affect insulin sensitivity and insulin secretion. Currently available data suggest that insulin resistance is the acquired defect largely secondary to unhealthy lifestyles and that the major genetic factor is impaired insulin secretion. The latter is the result of both redu...... hiện toàn bộ
EditorialSpringer Science and Business Media LLC - Tập 31 - Trang 1-1 - 2005
Martin J. Szanto
Use of antileukotriene agents in asthma managementSpringer Science and Business Media LLC - Tập 26 - Trang 31-38 - 2000
Sheldon L. Spector
Antileukotriene agents make up the newest class of antiasthma drugs. The results of clinical testing and post-marketing surveillance indicate that these agents are safe and well tolerated in patients with mild-to-moderate persistent asthma.
Effects of thiazolidinediones on cardiovascular risk factorsSpringer Science and Business Media LLC - Tập 28 - Trang 200-206 - 2002
Biswanath P. Gouda, Sunil Asnani, Vivian A. Fonseca
The thiazolidinediones are the insulin sensitizers used in the management of Type 2 diabetes mellitus. These drugs can potentially decrease the risk of cardiovascular disease by correcting the different components of the insulin resistance syndrome.
Systemic lupus erythematosus Current state of diagnosis and treatmentSpringer Science and Business Media LLC - Tập 32 - Trang 158-162 - 2018
Ioana Moldovan
Systemic lupus erythematosus is a chronic autoimmune condition with a wide spectrum of clinical manifestations, characterized by the production of auto-antibodies to components of the cell nucleus. Treatments include various immunosuppressive regimens, and newer biological therapies show promising results.
Recent advances in pharmacological treatment of type 2 diabetes mellitusSpringer Science and Business Media LLC - Tập 25 - Trang 418-426 - 1999
Akhil A. Parulkar, Vivian A. Fonseca
Several new pharmacological agents attempt to correct abnormalities in the pathogenesis of type 2 diabetes mellitus. The availability of agents with different mechanisms of action and side-effect profiles permits the design of individualized regimens that address the various pathophysiologic abnormalities.
Sudden unexpected deathSpringer Science and Business Media LLC - Tập 31 - Trang 176-180 - 2005
W. H. Wehrmacher, José Luis Puglisi, Donald M. Bers, Harry Messmore
Sudden unexpected death is a major public health problem. Many cases could be prevented if they were anticipated through means of a better awareness among the medical community, new therapies based on early genetic screening, or corrected by countershock.