The Effects of a Perindopril-Based Regimen in Relation to Statin Use on the Outcomes of Patients with Vascular Disease: a Combined Analysis of the ADVANCE, EUROPA, and PROGRESS TrialsSpringer Science and Business Media LLC - - Trang 1-9 - 2022
S. P. Radhoe, E. Boersma, M. Bertrand, W. Remme, R. Ferrari, K. Fox, S. MacMahon, J. Chalmers, M. L. Simoons, J. J. Brugts
To study the effects of a perindopril-based regimen on cardiovascular (CV) outcomes in patients with vascular disease in relation to background statin therapy. A pooled analysis of the randomized ADVANCE, EUROPA, and PROGRESS trials was performed to evaluate CV outcomes in 29,463 patients with vascular disease treated with perindopril-based regimens versus placebo. The primary endpoint was a compo...... hiện toàn bộ
Attenuation of myocardial reperfusion injury by sulfhydryl-containing angiotensin converting enzyme inhibitorsSpringer Science and Business Media LLC - Tập 6 - Trang 437-443 - 1992
Xuekun Liu, Richard M. Engelman, John A. Rousou, Gerald A. Cordis, Dipak K. Das
Recent studies have suggested the beneficial effects of angiotensin converting enzyme (ACE) inhibitors against myocardial ischemic-reperfusion injury. This study was designed to compare the cardioprotective effects of two sulfhydryl ACE inhibitors, captopril and zofenopril, with those of a nonsulfhydryl ACE inhibitor, fosinopril. The efficacy of these ACE inhibitors to scavenge oxygen radicals in ...... hiện toàn bộ
Recasting the approach to the treatment of potentially malignant ventricular arrhythmias after the cast studySpringer Science and Business Media LLC - Tập 4 - Trang 651-655 - 1990
A. Bayés de Luna, J. Guindo, J. Borja, M. Roman, C. Madoery
The best therapeutic approach to the therapy of potentially malignant ventricular arrhythmias is still unknown, particularly in view of the increased mortality with flecainide and encainide shown in the CAST study. Various ongoing studies, particularly with amiodarone, will show whether better results can be obtained with other agents. Flecainide and encainide do, however, have a restricted place ...... hiện toàn bộ