Psoriasis prediction from genome-wide SNP profilesSpringer Science and Business Media LLC - Tập 11 - Trang 1-8 - 2011
Shenying Fang, Xiangzhong Fang, Momiao Xiong
With the availability of large-scale genome-wide association study (GWAS) data, choosing an optimal set of SNPs for disease susceptibility prediction is a challenging task. This study aimed to use single nucleotide polymorphisms (SNPs) to predict psoriasis from searching GWAS data. Totally we had 2,798 samples and 451,724 SNPs. Process for searching a set of SNPs to predict susceptibility for psor...... hiện toàn bộ
Skin manifestations after bariatric surgerySpringer Science and Business Media LLC - Tập 20 - Trang 1-8 - 2020
Yada Itthipanichpong, Wilawan Damkerngsuntorn, Natsinee Tangkijngamvong, Suthep Udomsawaengsup, Patchaya Boonchayaanant, Chanat Kumtornrut, Stephen J. Kerr, Pravit Asawanonda, Pawinee Rerknimitr
Skin signs observed in morbid obesity may change as the weight reduces, especially post-bariatric surgery (BaS). Data concerning the skin findings exclusively in post-BaS patients remain limited. Seventy post-BaS patients were examined for cutaneous abnormalities. The patients were divided into those with successful weight loss (% excessive body weight loss (EBWL) of at least 50%) and a non-succes...... hiện toàn bộ
Personalized medicine in psoriasis: developing a genomic classifier to predict histological response to AlefaceptSpringer Science and Business Media LLC - Tập 10 Số 1 - 2010
Mayte Suárez‐Fariñas, Kejal Shah, Asifa Haider, James G. Krueger, Michelle A. Lowes
AbstractBackgroundAlefacept treatment is highly effective in a select group patients with moderate-to-severe psoriasis, and is an ideal candidate to develop systems to predict who will respond to therapy. A clinical trial of 22 patients with moderate to severe psoriasis treated with alefacept was conducted in 2002-2003, as a mecha...... hiện toàn bộ
Actinic keratoses in subjects from la Mitad del Mundo, EcuadorSpringer Science and Business Media LLC - Tập 20 - Trang 1-6 - 2020
Martha Fors, Paloma González, Carmen Viada, Kirsten Falcón, Santiago Palacios
Quito, the capital of Ecuador due to its geographical location, has a high skin cancer incidence. Actinic keratoses, as premalignant lesions, are precursors of nonmelanoma skin cancer, and the prevalence of this medical condition in the country is unknown. An observational, cross-sectional study was performed to assess the prevalence of actinic keratoses (AKs) in a rural area of Quito. Visual skin...... hiện toàn bộ
Plasma proteins in a standardised skin mini-erosion (I): permeability changes as a function of timeSpringer Science and Business Media LLC - Tập 2 - Trang 1-7 - 2002
Christer Svedman, Bing B Yu, Terence J Ryan, Henry Svensson
A standardised technique using a suction-induced mini-erosion that allows serial sampling of dermal interstitial fluid (IF) for 5 to 6 days has been described. In the present study, we studied permeability changes as a function of time. We examined IF concentrations of total protein concentration and the concentration of insulin (6.6 kDa), prealbumin (55 kDa), albumin (66 kDa), transferrin (80 kDa...... hiện toàn bộ
A case report of erythroderma in a patient with borderline leprosy on reversal reaction: a result of the exacerbated reaction?Springer Science and Business Media LLC - Tập 17 - Trang 1-5 - 2017
Denis Miyashiro, Ana Paula Vieira, Maria Angela Bianconcini Trindade, João Avancini, José Antonio Sanches, Gil Benard
Erythroderma is characterized by erythema and scaling affecting more than 90% of the body surface area. Inflammatory, neoplastic and, more rarely, infectious diseases may culminate with erythroderma. Diagnosis of the underlying disorder is therefore crucial to institute the appropriate therapy. Leprosy is a chronic infectious disease that is endemic in Brazil. Here we present an unusual case of le...... hiện toàn bộ