S. Karger AG
1424-8832
1424-8840
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Các bài báo tiêu biểu
Calibrated Automated Thrombin Generation Measurement in Clotting PlasmaCalibrated automated thrombography displays the concentration of thrombin in clotting plasma with or without platelets (platelet-rich plasma/platelet-poor plasma, PRP/PPP) in up to 48 samples by monitoring the splitting of a fluorogenic substrate and comparing it to a constant known thrombin activity in a parallel, non-clotting sample. Thus, the non-linearity of the reaction rate with thro... ...
Tập 33 Số 1 - Trang 4-15 - 2003
Atrial Fibrillation and the Hypercoagulable State: From Basic Science to Clinical Practice
Tập 33 Số 5-6 - Trang 282-289 - 2003
Factor VIII Inhibitor-Bypassing Agents Act by Inducing Thrombin Generation and Can Be Monitored by a Thrombin Generation AssayFactor VIII (FVIII)-bypassing agents have complex modes of action but all control bleeding in inhibitor patients by triggering the generation of thrombin. No routine test is available for monitoring this therapy in patients with inhibitors against FVIII. We present an assay that records FEIBA- or FVIIa-mediated changes in thrombin generation (TG) in FVIII inhibitor plasma samples. In plasm... ...
Tập 33 Số 1 - Trang 16-22 - 2003
The insulin resistance syndrome: implications for thrombosis and cardiovascular disease
Tập 32 Số 5-6 - Trang 269-273 - 2002
Pathogenesis of the acute coronary syndromes and therapeutic implications
Tập 32 Số 5-6 - Trang 225-231 - 2002
Structure-Function Relationships of C-Type Lectin-Related ProteinsThe structural and functional studies of the first identified C-type lectin-like protein (CLP), blood coagulation factor IX/factor X-binding protein (IX/X-bp), have been instrumental in defining how new functionally heterodimeric CLPs are generated from monomeric carbohydrate recognition domain in C-type lectins by three-dimensional domain swapping. The crystal structures of γ-carboxygluta... ...
Tập 34 Số 4-5 - Trang 156-159 - 2005
The Prothrombinase-Induced Clotting Test: A New Technique for the Monitoring of Anticoagulants
Tập 30 Số 2 - Trang 172-174 - 2000