S. Karger AG
SCOPUS (2003-2014)
1660-2110
Cơ quản chủ quản: N/A
Các bài báo tiêu biểu
Efficacy, Tolerability, and Safety of Lanthanum Carbonate in Hyperphosphatemia: A 6-Month, Randomized, Comparative Trial versus Calcium Carbonate
Tập 100 Số 1 - Trang c8-c19
Background/Aims: Hyperphosphatemia is an important clinical consequence
of renal failure, and its multiple adverse systemic effects are associated with
significantly increased risks of morbidity and mortality in dialysis patients.
Existing oral phosphate binders have not permitted control of serum phosphate
within currently accepted guidelines. This study compares lanthanum carbonate
with c...
Clinical Trial Endpoints in Acute Kidney Injury
Tập 127 Số 1-4 - Trang 89-93
The development and use of consensus criteria for acute kidney injury (AKI)
diagnosis and the inclusion of recently identified markers of renal parenchymal
damage as endpoints in clinical trials have improved the ability of physicians
to compare the incidence and severity of AKI across patient populations,
provided targets for testing new treatments, and may increase insight into the
mechanisms of...
Accelerated Progression of Calcific Aortic Stenosis in Dialysis Patients
Tập 94 Số 2 - Trang c40-c45
Background: Abnormalities of the aortic valve occur with increased
frequency in patients with renal failure and may contribute to the observed
excess cardiovascular mortality. Little data exist on the rate at which aortic
stenosis progresses in this patient group. Methods: A retrospective
case-control study was designed to compare the rate of progression of aortic
stenosis in dialysi...
Long-Term Efficacy and Tolerability of Lanthanum Carbonate: Results from a 3-Year Study
Tập 102 Số 2 - Trang c61-c71
Background: Control of serum phosphate over the long term is essential in
patients with end-stage renal disease. Six-month and 2-year extensions to a
6-month study evaluated the long-term safety, tolerability and efficacy of the
new phosphate binder lanthanum carbonate. Methods: Patients who
participated in a 6-month, randomized trial comparing lanthanum carbonate with
calcium carbon...
Deficient Counseling on Physical Activity among Nephrologists
Tập 116 Số 4 - Trang c330-c336
Background: An evaluation of exercise counseling practices among
nephrologists in 2001 demonstrated few clinicians assessing patients’ levels of
physical activity (PA) and counseling to increase activity. Recent Kidney
Disease Outcomes Quality Initiative (KDOQI) cardiovascular guidelines
recommended that nephrologists counsel patients to increase PA. Our objective
was to ascertain whether n...
Acute and Transient Podocyte Loss and Proteinuria in Preeclampsia
Tập 112 Số 2 - Trang c65-c70
Glomerular podocytes are known to regulate proteinuria and podocyturia
correlated with proteinuria. Podocyturia, the urinary excretion of viable
podocytes (glomerular epithelial cells), has been associated with proteinuria in
preeclampsia. This study is the first to investigate the time course alterations
of podocyturia in patients with preeclampsia (11 cases) and normotensive
pregnant women (45 c...
Blood Pressure Control and Symptomatic Intradialytic Hypotension in Diabetic Haemodialysis Patients: A Cross-Sectional Survey
Tập 109 Số 2 - Trang c65-c71
Background:Cardiovascular disease remains the most common cause of
mortality in end-stage kidney failure patients with diabetes. To improve blood
pressure control, and reduce cardiovascular risk, in 2002 the UK Renal
Association Standards’ Committee introduced pre- and post-dialysis target blood
pressures of <140/90 and <130/80 mm Hg, respectively. Methods: We audited
blood pressure ...
Vascular Calcification in Chronic Renal Failure
Tập 93 Số 4 - Trang c124-c130
The prevalence and extent of vascular calcification (VC) increases rapidly with
time on dialysis. There is increasing evidence that medial calcification of
conduit arteries, without intimal disease, is associated with important
abnormalities of vascular compliance and increased risk of cardiovascular death.
Coronary artery calcification is also common in end-stage renal disease, but
further resear...
Chronic Kidney Disease and the Ageing Population
Tập 128 Số 3-4 - Trang 319-322
Due to improvements in socioeconomic development and increased life expectancy,
the proportion of older people in the general population is increasing
worldwide. While this trend is something to celebrate, it also brings with it
challenges for health care systems. One particular challenge is an increase in
chronic kidney disease, the prevalence of which is higher in older people. This
article revi...