Respirology
SCOPUS (1996-2025)SCIE-ISI
1440-1843
1323-7799
Anh Quốc
Cơ quản chủ quản: WILEY , Wiley-Blackwell Publishing Ltd
Lĩnh vực:
Pulmonary and Respiratory Medicine
Các bài báo tiêu biểu
The airway epithelium: Structural and functional properties in health and disease
Tập 8 Số 4 - Trang 432-446 - 2003
Abstract: The major function of the respiratory epithelium was once thought to
be that of a physical barrier. However, it constitutes the interface between the
internal milieu and the external environment as well as being a primary target
for inhaled respiratory drugs. It also responds to changes in the external
environment by secreting a large number of molecules and mediators that signal
to cel...
Diagnostic yield of transbronchial cryobiopsy in interstitial lung disease: A randomized trial
Tập 19 Số 6 - Trang 900-906 - 2014
AbstractBackground and objectiveTransbronchial lung biopsy (TBLB) is required
for evaluation in selected patients with interstitial lung disease (ILD). The
diagnostic yield of histopathologic assessment is variable and is influenced by
factors such as the size of samples and the presence of crush artefacts left by
conventional biopsy forceps. We compared the diagnostic yield and safety of TBLB
wit...
Women and tobacco
Tập 8 Số 2 - Trang 123-130 - 2003
Abstract: Smoking prevalence is lower among women than men in most countries,
yet there are about 200 million women in the world who smoke, and in addition,
there are millions more who chew tobacco. Approximately 22% of women in
developed countries and 9% of women in developing countries smoke, but because
most women live in developing countries, there are numerically more women
smokers in develo...
Silica‐associated lung disease: An old‐world exposure in modern industries
Tập 24 Số 12 - Trang 1165-1175 - 2019
ABSTRACTDespite silica dust exposure being one of the earliest recognized causes
of lung disease, Australia, USA, Israel, Turkey and other countries around the
world have recently experienced significant outbreaks of silicosis. These
outbreaks have occurred in modern industries such as denim jean production,
domestic benchtop fabrication and jewellery polishing, where silica has been
introduced wi...
Obesity and craniofacial structure as risk factors for obstructive sleep apnoea: Impact of ethnicity
Tập 17 Số 2 - Trang 213-222 - 2012
ABSTRACTOSA is the result of structural and functional abnormalities that
promote the repetitive collapse of the upper airway during sleep. This common
disorder is estimated to occur in approximately 4% of men and 2% of women, with
prevalence studies from North America, Australia, Europe and Asia indicating
that occurrence is relatively similar across the globe. Anatomical factors, such
as obesity...
The immunology of tuberculosis: From bench to bedside
Tập 15 Số 3 - Trang 433-450 - 2010
ABSTRACTTuberculosis (TB) is an international public health priority and kills
almost two million people annually. TB is out of control in Africa due to
increasing poverty and HIV coinfection, and drug‐resistant TB threatens to
destabilize TB control efforts in several regions of the world. Existing
diagnostic tools and therapeutic interventions for TB are suboptimal. Thus, new
vaccines, immunothe...
Bronchial epithelial cells: The key effector cells in the pathogenesis of chronic obstructive pulmonary disease?
Tập 20 Số 5 - Trang 722-729 - 2015
AbstractThe primary function of the bronchial epithelium is to act as a
defensive barrier aiding the maintenance of normal airway function. Bronchial
epithelial cells (BEC) form the interface between the external environment and
the internal milieu, making it a major target of inhaled insults. However, BEC
can also serve as effectors to initiate and orchestrate immune and inflammatory
responses by...
Pollen proteolytic enzymes degrade tight junctions
Tập 12 Số 6 - Trang 834-842 - 2007
Background and objective: Asthma and allergic rhinitis are significant,
increasing causes of morbidity worldwide. Pollen, a major cause of seasonal
rhinitis/conjunctivitis, carries proteolytic enzymes on its surface. We showed
previously that peptidase allergens from house dust mites compromise epithelial
barrier function by degrading the extracellular domains of the tight junction
proteins, occl...
Obesity, obstructive sleep apnoea and metabolic syndrome
Tập 17 Số 2 - Trang 223-236 - 2012
ABSTRACTOSA is increasingly recognized as a major health problem in developed
countries. Obesity is the most common risk factor in OSA and hence, the
prevalence of OSA is undoubtedly rising given the epidemic of obesity. Recent
data also suggest that OSA is highly associated with the metabolic syndrome, and
it is postulated that OSA contributes to cardiometabolic dysfunction, and
subsequently vasc...
The role of acute and chronic respiratory colonization and infections in the pathogenesis of COPD
Tập 22 Số 4 - Trang 634-650 - 2017
ABSTRACT COPD is a major global concern, increasingly so in the context of
ageing populations. The role of infections in disease pathogenesis and
progression is known to be important, yet the mechanisms involved remain to be
fully elucidated. While COPD pathogens such as Haemophilus influenzae, Moraxella
catarrhalis and Streptococcus pneumoniae are strongly associated with acute
exacerbations of C...