Reproductive Sciences

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Association of miR-27aA>G, miR-423C>a, miR-449bA>G, and miR-604A>G Polymorphisms with Risk of Recurrent Implantation Failure
Reproductive Sciences - Tập 27 - Trang 29-38 - 2020
Jung Oh Kim, Eun Hee Ahn, Jung Hyun Sakong, Hui Jeong An, Han Sung Park, Young Ran Kim, Jung Ryeol Lee, Woo Sik Lee, Nam Keun Kim
Recurrent implantation failure (RIF) is defined when pregnancy failure occurs after two consecutive in vitro fertilization-embryo transfers to the endometrium using at least four high-quality embryos in women. MicroRNAs are well-known function modulators and are involved in many diseases. Recently, studies on microRNA and recurrent pregnancy loss (RPL) have been actively carried out; however, sing...... hiện toàn bộ
Providing a “Noah’s Ark” for Research in the Reproductive Sciences by Fostering Young Investigators: A Role for Our Journal
Reproductive Sciences - Tập 1 - Trang 246-246 - 1994
Frederick Naftolin, Tamas Horvath
MicroRNA-135a Regulates VEGFC Expression and Promotes Luteinized Granulosa Cell Apoptosis in Polycystic Ovary Syndrome
Reproductive Sciences - Tập 27 - Trang 1436-1442 - 2020
Yifang Wei, Shenglian Lu, Yu Hu, Li Guo, Xiaoyu Wu, Xing Liu, Yun Sun
Androgen is known to regulate microRNA-135a (miR-135a) and can be regulated by androgen, suggesting that it may contribute to polycystic ovary syndrome (PCOS) with hyperandrogenism. However, its roles and mechanisms of action in PCOS are unknown. In this study, the role and molecular mechanisms underlying miR-135a in granulosa cells (GCs) in PCOS were evaluated. miR-135a expression was upregulated...... hiện toàn bộ
Ovarian Changes After Abdominal Hysterectomy for Benign Conditions
Reproductive Sciences - - 2005
Carina C. W. Chan, Ernest H. Y. Ng, Pak-Chung Ho
To investigate any change in the ovaries, including early follicular serum follicle-stimulating hormone (FSH) level, total ovarian volume, total antral follicle count, and ovarian stromal blood flow, in patients who had undergone abdominal hysterectomy for benign conditions. Fifteen women with abdominal hysterectomy and conservation of ovaries for benign conditions and who were between 29 and 44 y...... hiện toàn bộ
Altered Energy Metabolism, Mitochondrial Dysfunction, and Redox Imbalance Influencing Reproductive Performance in Granulosa Cells and Oocyte During Aging
Reproductive Sciences - - 2024
Hiroshi Kobayashi, Chiharu Yoshimoto, Sho Matsubara, Hiroshi Shinmoto, Shogo Imanaka
Characterization of Paracellular Permeability in Cultured Human Cervical Epithelium: Regulation by Extracellular Adenosine Triphosphate
Reproductive Sciences - Tập 1 - Trang 225-233 - 1994
George I. Gorodsski, Didier Merlin, Brian J. De Santis, Kimberley A. Frieden, Ulrich Hopfer, Richard L. Eckert, Wulf H. Utian, Michael F. Romero
The purpose of the present study was to compare the permeaiility and regulation of paracellular transport in human cervical cells with those in epithelial cells of other organs. Cervical cells (ECE16–1, Caski, and HT3) were grown on filters, and trans-epithelial electrical conductance (GT) and the permeability to pyranine (PPyr) were determined. Cervical cultures were characterized by high GT (83–...... hiện toàn bộ
Higher PAPP-A Values in Pregnant Women Complicated with Preeclampsia Than with Gestational Hypertension
Reproductive Sciences - Tập 30 - Trang 2503-2511 - 2023
Montserrat Uriel, Ximena Carolina Romero Infante, Sara Rincón Franco, Edgar Antonio Ibáñez Pinilla, Nydia Alexandra Rojas
The purpose of this study is to compare the levels of maternal serum pregnancy–associated plasma protein-A at the first trimester in pregnancies complicated by impaired placental diseases, such as preeclampsia (PE), intrauterine fetal growth restriction (IUGR), and gestational hypertension (GH), with those in pregnancies without the development of any of these outcomes to expand the knowledge of h...... hiện toàn bộ
Plasma and Renal Renin Concentrations in Adult Sheep After Prenatal Betamethasone Exposure
Reproductive Sciences - Tập 15 - Trang 831-838 - 2008
Lucia Kantorowicz, Nancy K. Valego, LiJun Tang, Jorge P. Figueroa, Mark C. Chappell, Luke C. Carey, James C. Rose
This study examined whether renin expression and secretion and plasma angiotensin II (Ang II) levels were altered in adult sheep exposed to antenatal betamethasone. Pregnant sheep received injections of 0.17 mg/kg betamethasone or vehicle, at 80 and 81 days of gestation, and offspring were studied at 6 and 18 months of age. At 6 months, plasma prorenin concentrations were significantly lower in be...... hiện toàn bộ
Hyperandrogenism Induces Histo-Architectural Changes in the Rat Uterus
Reproductive Sciences - Tập 26 - Trang 657-668 - 2019
Gisela Soledad Bracho, Gabriela Anahí Altamirano, Laura Kass, Enrique Hugo Luque, Verónica Lis Bosquiazzo
The effects of androgens on the uterus have been poorly studied and they need to be clarified to understand why androgen excess, such as observed in women with polycystic ovary syndrome (PCOS), is a risk factor for the development of endometrial hyperplasia, cancer, and infertility. Thus, uterine histomorphology in a PCOS experimental model was evaluated. Beginning at weaning, female rats were inj...... hiện toàn bộ
Innate Immunity, Decidual Cells, and Preeclampsia
Reproductive Sciences - Tập 20 - Trang 339-353 - 2013
Chang-Ching Yeh, Kuan-Chong Chao, S. Joseph Huang
Preeclampsia (PE) manifested by hypertension and proteinuria complicates 3% to 8% of pregnancies and is a leading cause of fetal–maternal morbidity and mortality worldwide. It may lead to intrauterine growth restriction, preterm delivery, and long-term sequelae in women and fetuses, and consequently cause socioeconomic burden to the affected families and society as a whole. Balanced immune respons...... hiện toàn bộ
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