Reproductive Sciences

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Enhanced Expression of P2X4 and P2X7 Purinergic Receptors in the Myometrium of Pregnant Rats in Preterm Delivery Models
Reproductive Sciences - Tập 16 - Trang 1186-1192 - 2009
Satoshi Urabe, Hiroshi Miyoshi, Hisaya Fujiwara, Kaoru Yamaoka, Yoshiki Kudo
The expression levels of P2X purinergic receptors were determined in the myometrium of pregnant rats using the quantitative real-time reverse transcriptase polymerase chain reaction (RT-PCR). The messenger RNAs (mRNAs) of P2X4 and P2X7 were expressed most strongly. The expression levels of these receptors increased during the late stages of pregnancy; at the time of delivery, the mRNA levels of P2...... hiện toàn bộ
Comments on “rhTNFR:Fc Suppresses the Development of Endometriosis in a Mouse Model by Downregulating Cell Proliferation and Invasiveness”
Reproductive Sciences - Tập 25 - Trang 983-984 - 2018
Antonio Simone Laganà, Francesca Maria Salmeri, Onofrio Triolo, Salvatore Giovanni Vitale, Roberta Granese, Vincenza Sofo
The Effect of Mild Hypothermia on Insulin-like Growth Factors After Severe Asphyxia in the Preterm Fetal Sheep
Reproductive Sciences - Tập 12 - Trang 232-237 - 2005
Vincent Roelfsema, Alistair Jan Gunn, Bernhard H. Breier, Josine S. Quaedackers, Laura Bennet
Persistent reductions in insulin-like growth factor I (IGF-I) levels in the preterm infant are strongly associated with increased risk of retinopathy and other complications, and may result from exposure to severe hypoxia. The effects of a potential new treatment for hypoxic-ischemic encephalopathy, cerebral hypothermia, on the responses of the IGF axis to hypoxia are unknown. The aim of this stud...... hiện toàn bộ
Decreased Frequency of CD8+HLA-G+ T Cell in the Peripheral Blood of Primary Unexplained Infertile Females
Reproductive Sciences - Tập 28 - Trang 1939-1944 - 2021
Motahareh Ehsani, Mousa Mohammadnia-Afrouzi, Sedigheh Esmaeilzadeh, Zahra Tajalli, Mohammad Jafari, Mehdi Shahbazi
Most of the findings have focused on the importance of CD4+HLA-G+ and CD8+HLA-G+ regulatory T cells (Treg) during pregnancy. It has been demonstrated that these HLA-G+ T cell subsets could induce maternal immune tolerance against semi-allogenic conceptus during pregnancy. There are only a few experiments regarding the Treg cells in the context of unexplained infertility (UI). Thirty-five participa...... hiện toàn bộ
Molecular Background of Estrogen Receptor Gene Expression in Endometriotic Cells
Reproductive Sciences - Tập 23 - Trang 871-876 - 2016
Masao Izawa, Fuminori Taniguchi, Tasuku Harada
The molecular background of estrogen receptor (ER) expression is important to understand the pathophysiology of the high estrogen environment in endometriosis. However, the molecular details have not been fully understood. The objective of this study is to evaluate the molecular background of ERα and ERβ messenger RNA (mRNA) expression in endometriotic cells. The following summarizes our observati...... hiện toàn bộ
Current Perspectives in Uterine Research: Reviews From the Society for Gynecologic Investigation Myometrium and Parturition Satellite Symposia
Reproductive Sciences - Tập 20 - Trang 138-139 - 2013
Michael J. Taggart, R. Ann Word
1-DNJ Alleviates Obesity-Induced Testicular Inflammation in Mice Model by Inhibiting IKKβ/ NF-kB Pathway
Reproductive Sciences -
Wenli Mai, Yi Shang, Yibin Wang, Huiling Chen, Bo Mu, Qingyin Zheng, H Y Liu
AbstractObesity is associated with chronic inflammation that affects various organs in the body, including the reproductive system, which is a key factor in male infertility. 1-Deoxynojirimycin (1-DNJ) is a natural alkaloid in mulberry leaves, which has anti-inflammatory capabilities, yet, it’s effects on obesity-induced inflammation-related male infertility remain...... hiện toàn bộ
Cellular Metabolism: Contribution to Postoperative Adhesion Development
Reproductive Sciences - Tập 16 - Trang 627-634 - 2009
Valerie I. Shavell, Ghassan M. Saed, Michael P. Diamond
Postoperative adhesions are a significant source of morbidity, including contributions to pelvic pain, bowel obstruction, and infertility. While the mechanisms of postoperative adhesion development are complex and incompletely understood, hypoxia appears to trigger a cascade of intracellular responses involving hypoxia-inducible factors, lactate, reactive oxygen species, reactive nitrogen species,...... hiện toàn bộ
The Effect of Exercise During Pregnancy on Maternal and Offspring Vascular Outcomes: a Pilot Study
Reproductive Sciences - Tập 28 - Trang 510-523 - 2020
Áine Brislane, Helen Jones, Sophie M. Holder, David A. Low, Nicola D. Hopkins
The aim of this pilot study is to obtain estimates for the change in maternal cerebrovascular (primary) and offspring vascular structure (secondary) during healthy pregnancy that includes structured exercise. Eighteen pregnant women self-assigned to a moderate-intensity aerobic exercise intervention or a control group. Maternal cerebral blood flow (CBF) at the middle cerebral artery, cerebro- and ...... hiện toàn bộ
BDNF and TrkB in the Preterm and Near-term Ovine Fetal Brain and the Effect of Intermittent Umbilical Cord Occlusion
Reproductive Sciences - Tập 15 - Trang 895-905 - 2008
Hidekazu Nishigori, Delfina M. Mazzuca, Karen L. Nygard, Victor K. Han, Bryan S. Richardson
We have determined the developmental change in immunoreactivity for brain-derived neurotrophic factor and its high-affinity tyrosine kinase receptor, TrkB, in the ovine fetal brain with advancing gestation and in response to intermittent umbilical cord occlusion, which might then contribute to adverse neurodevelopment. Fetal sheep (control and experimental groups at 0.75 and 0.90 of gestation) wer...... hiện toàn bộ
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