Pulmonary Therapy
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Identifying Critical Errors: Addressing Inhaler Technique in the Context of Asthma Management
Pulmonary Therapy - Tập 4 - Trang 1-12 - 2018
Medication use has always played a highly significant role in the overall
management of asthma, with appropriate use being linked to good asthma control.
However, while patients with asthma enjoy the ‘luxury’ of having medications
delivered directly to the lungs via inhaler devices, with that comes the
additional challenge of ensuring that inhaler devices are used correctly.
Research and practice ...
Ex Vivo Lung Perfusion: A Review of Current and Future Application in Lung Transplantation
Pulmonary Therapy - Tập 8 - Trang 149-165 - 2022
The number of waitlisted lung transplant candidates exceeds the availability of
donor organs. Barriers to utilization of donor lungs include suboptimal lung
allograft function, long ischemic times due to geographical distance between
donor and recipient, and a wide array of other logistical and medical
challenges. Ex vivo lung perfusion (EVLP) is a modality that allows donor lungs
to be evaluated ...
A Real-Life One-Year Non-Interventional Study Assessing Safety, Tolerability, and Treatment Outcome of the SQ HDM SLIT-Tablet (Acarizax®) in House Dust Mite Allergic Rhinitis With or Without Asthma
Pulmonary Therapy - Tập 7 - Trang 221-236 - 2021
The aim of this study was to investigate the safety profile, tolerability, and
outcome of the SQ® house dust mite (HDM) sublingual immunotherapy (SLIT)-tablet
after 1 year of treatment in clinical practice among adults with HDM-related
allergic rhinitis (AR) ± allergic asthma (AA). In a non-interventional
multicenter, observational study, patients were followed at 3 visits for 1 year.
Adverse even...
COPD and Singing for Lung Health: A Patient and Clinician Perspective
Pulmonary Therapy - Tập 4 - Trang 121-124 - 2018
This article, co-authored by a patient living with chronic obstructive pulmonary
disease (COPD) and a respiratory physiotherapist, discusses the patient’s
experience of COPD and singing as a form of therapy. The clinician then
discusses his experience of Singing for Lung Health in the context of the
patient, and how more research is needed in this area.
Patient and Clinical Demographics of New Users to Single-Inhaler Triple Therapy in Patients with Chronic Obstructive Pulmonary Disease
Pulmonary Therapy - Tập 8 - Trang 195-208 - 2022
Single-inhaler fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) triple
therapy was approved by the United States Food and Drug Administration in 2017
as a maintenance therapy for chronic obstructive pulmonary disease (COPD).
Patient characteristics and treatment patterns prior to initiating FF/UMEC/VI
are currently unknown. This study assessed patient characteristics,
exacerbation, and med...
Medication Adherence and Asthma Control with Once-Daily Indacaterol/Glycopyrronium/Mometasone Furoate Breezhaler Digital Companion: 90-Day Analysis from Germany
Pulmonary Therapy - Tập 9 - Trang 429-434 - 2023
Suboptimal adherence to inhaled asthma therapy is associated with poor clinical
outcomes. Digital companion paired inhaler devices record medication use and
provide reminders, thereby improving treatment adherence and asthma outcomes.
This analysis assessed the impact of indacaterol/glycopyrronium/mometasone
furoate (IND/GLY/MF) Breezhaler® digital companion on medication adherence and
symptom con...
The Use of Therapeutic Plasma Exchange in the Treatment of a Pregnant Woman with COVID-19 Induced Acute Respiratory Distress Syndrome
Pulmonary Therapy - Tập 8 - Trang 233-240 - 2022
A 27-year-old woman at 17 weeks gestation was admitted to the intensive care
unit (ICU) with a history of fever, dyspnea, and dry cough for 3 days. She was
diagnosed with coronavirus disease 2019 (COVID-19) based on her nasopharyngeal
swab polymerase chain reaction (PCR) that was positive for severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). In the ICU, the patient
developed acute resp...
An Open-Label, Phase II Study of the Safety of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis (PIPF-002)
Pulmonary Therapy - Tập 4 - Trang 59-71 - 2018
PIPF-002 was a phase 2, multicenter, open-label study of pirfenidone in patients
with idiopathic pulmonary fibrosis (IPF) or other types of pulmonary fibrosis
(PF). PIPF-002 terminated after pirfenidone became commercially available in the
United States. The goal of PIPF-002 was to characterize the long-term safety of
pirfenidone in these patients. Between August 2003 and September 2006, 83
patien...
Understanding the Burden of Respiratory Syncytial Virus in Older Adults in Latin America: An Expert Perspective on Knowledge Gaps
Pulmonary Therapy - - Trang 1-20 - 2024
Respiratory syncytial virus (RSV) is a significant global health concern and
major cause of hospitalization, particularly among infants and older adults. The
clinical impact of RSV is well characterized in infants; however, in many
countries, the burden and risk of RSV in older populations are overlooked. In
Latin America, there are limited data on RSV epidemiology and disease management
in older ...
Forced Expiratory Flow (FEF25–75%) as a Clinical Endpoint in Children and Adolescents with Symptomatic Asthma Receiving Tiotropium: A Post Hoc Analysis
Pulmonary Therapy - Tập 6 - Trang 151-158 - 2020
In pediatric patients with asthma, measurements of forced expiratory volume in
1 s (FEV1) may be normal or may not correlate with symptom severity. Forced
expiratory flow at 25–75% of the vital capacity (FEF25–75%) is a potentially
more sensitive parameter for assessing peripheral airway function. This post hoc
analysis compared FEF25–75% with FEV1 as an endpoint to assess bronchodilator
responsiv...
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