Autologous Blood Patch Pleurodesis for Secondary Spontaneous Pneumothorax: A Narrative Review, a Retrospective Case Series and State of Play in the UK

Sufyan Shakir1, Brian Choo-Kang2, Clare Ross3, Kevin Conroy4, Richard Thorley5, Steven Walker6, Rahul Bhatnagar6, Avinash Aujayeb1
1Department of Respiratory Medicine, Northumbria Healthcare NHS Trust, Northumbria Way, Cramlington, NE23 6NZ, UK
2Department of Respiratory Medicine, Glasgow Royal Infirmary, 84 Castle Street, Glasgow, G4 0SF, UK
3Imperial College NHS Trust, Exhibition Rd, South Kensington, London, SW7 2BX, UK
4North Tees and Hartlepool NHS Foundation Trust, University Hospital of North Tees, Hardwick Road, Stockton On Tees, Cleveland, TS19 8PE, UK
5Departement of Respiratory Medicine, North Devon District Hospital, Raleigh Heights, Barnstaple, EX31 4JB, UK
6Academic Respiratory Unit, 2nd Floor, Learning and Research, Southmead Hospital, Westbury-On-Trym, Bristol, BS10 5NB, UK

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MacDuff A, Arnold A, Harvey J. Management of spontaneous pneumothorax: British Thoracic Society pleural disease guideline 2010. Thorax. 2010;65:18–31. https://doi.org/10.1136/thx.2010.136986.

Hallifax R. Aetiology of primary spontaneous pneumothorax. J Clin Med. 2022;11(3):490. https://doi.org/10.3390/jcm11030490.

Aragaki-Nakahodo A. Management of pneumothorax: an update. Curr Opin Pulm Med. 2022;28(1):62–7. https://doi.org/10.1097/mcp.0000000000000839.

Chee CB, Abisheganaden J, Yeo JK, et al. Persistent air-leak in spontaneous pneumothorax – clinical course and outcome. Respir Med. 1998;92:757–61. https://doi.org/10.1016/s0954-6111(98)90008-7.

BTS Guideline for Pleural Disease. https://www.brit-thoracic.org.uk/media/455873/bts-guideline-for-pleural-disease-consultation-jun-2022.pdf. Accessed 15 Oct 2022.

van Dijk M, Sue R, Criner GJ, Gompelmann D, Herth FJF, Hogarth DK, Klooster K, Kocks JWH, de Oliveira HG, Shah PL, Valipour A, Slebos DJ. Expert statement: pneumothorax associated with one-way valve therapy for emphysema: 2020 update. Respiration. 2021;100(10):969–78 (10.1159%2F000516326).

Hallifax RJ, Yousuf A, Jones HE, Corcoran JP, Psallidas I, Rahman NM. Effectiveness of chemical pleurodesis in spontaneous pneumothorax recurrence prevention: a systematic review. Thorax. 2017;72(12):1121–31. https://doi.org/10.1136/thoraxjnl-2015-207967.

Aujayeb A. Spontaneous pneumothorax: new horizons. Journal of Respiration. 2021;1(1):80–3. https://doi.org/10.3390/jor1010008.

Shafiq M, Banka R, Bain PA, Mahmood K, Rahman NM, Cheng G. Autologous blood patch for persistent air leak following secondary spontaneous pneumothorax: a systematic review. J Bronchol Interv Pulmonol. 2022. https://doi.org/10.1097/lbr.0000000000000891.

UK Pleural Society. https://www.pleura.org.uk/. Accessed 15 Oct 2022.

2013 CARE Checklist. https://www.care-statement.org/checklist. Accessed 15 Oct 2022.

Muruganandan S, Kumar S, Lee YCG. Blood patch for pneumothorax: a literature review. Curr Pulmonol Rep. 2017;6:30–8. https://doi.org/10.1007/s13665-017-0163-2.

Lang-Lazdunski L, Coonar AS. A prospective study of autologous “blood patch” pleurodesis for persistent air leak after pulmonary resection. Eur J Cardiothorac Surg. 2004;26(5):897–900. https://doi.org/10.1016/j.ejcts.2004.07.034.

Ahmed A, Page RD. The utility of intrapleural instillation of autologous blood for prolonged air leak after lobectomy. Curr Opin Pulm Med. 2008;14(4):343–7. https://doi.org/10.1097/mcp.0b013e3282fcea76.

Droghetti A, Schiavini A, Muriana P, et al. Autologous blood patch in persistent air leaks after pulmonary resection. J Thorac Cardiovasc Surg. 2006;132:556–9. https://doi.org/10.1016/j.jtcvs.2006.05.033.

Andreetti C, Venuta F, Anile M, De Giacomo T, Diso D, Di Stasio M, Rendina EA, Coloni GF. Pleurodesis with an autologous blood patch to prevent persistent air leaks after lobectomy. J Thorac Cardiovasc Surg. 2007;133(3):759–62. https://doi.org/10.1016/j.jtcvs.2006.10.042.

Mitchem RE, Herndon BL, Fiorella RM, Molteni A, Battie CN, Reisz GR. Pleurodesis by autologous blood, doxycycline, and talc in a rabbit model. Ann Thorac Surg. 1999;67(4):917–21. https://doi.org/10.1016/s0003-4975(99)00160-5.

Dumire R, Crabbe MM, Mappin FG, Fontenelle LJ. Autologous “blood patch” pleurodesis for persistent pulmonary air leak. Chest. 1992;101(1):64–6. https://doi.org/10.1378/chest.101.1.64.

Shaw JA, Wilken E, Allwood BW, Irusen EM, Koegelenberg CFN. Autologous blood patch pleurodesis for the management of a persistent air leak after secondary spontaneous pneumothorax. Respiration. 2022;101(4):417–21. https://doi.org/10.1159/000520656.

Aihara K, Handa T, Nagai S, Tanizawa K, Watanabe K, Harada Y, et al. Efficacy of blood-patch pleurodesis for secondary spontaneous pneumothorax in interstitial lung disease. Intern Med. 2011;50(11):1157–62. https://doi.org/10.2169/internalmedicine.50.4645.

Ibrahim IM, Elaziz MEA, El-Hag-Aly MA. Early autologous blood-patch pleurodesis versus conservative management for treatment of secondary spontaneous pneumothorax. Thorac Cardiovasc Surg. 2019;67(3):222–6. https://doi.org/10.1055/s-0038-1642028.

Cao G, Kang J, Wang F, Wang H. Intrapleural instillation of autologous blood for persistent air leak in spontaneous pneumothorax in patients with advanced chronic obstructive pulmonary disease. Ann Thorac Surg. 2012;93(5):1652–7. https://doi.org/10.1016/j.athoracsur.2012.01.093.

Evman S, Alpay L, Metin S, Kiral H, Demir M, Yalcinsoy M, et al. The efficacy and economical benefits of blood patch pleurodesis in secondary spontaneous pneumothorax patients. Kardiochir Torakochirurgia Pol. 2016;13(1):21–5. https://doi.org/10.5114/kitp.2016.58960.

Ando MYM, Kitagana C, et al. Autologous blood patch pleurodesis for secondary spontaneous pneumothorax with persistent air leak. Respir Med. 1999;93:432–4. https://doi.org/10.1053/rmed.1999.0567.

Rinaldi S, Felton T, Bentley A. Blood pleurodesis for the medical management of pneumothorax. Thorax. 2009;64:258–60. https://doi.org/10.1136/thx.2007.089664.

Brightling C, Genton C, Bill W, Welte T, Gaga M, Heuvelin E, Brusselle G. ERS Clinical Research Collaborations: underpinning research excellence. Eur Respir J. 2018;52(3):1801534. https://doi.org/10.1183/13993003.01534-2018.

Bhatnagar R, Janssen J, Maskell N. The International Collaborative Effusion (ICE) database: an ERS Clinical Research Collaboration. Eur Respir J. 2019;53(5):1900591. https://doi.org/10.1183/13993003.00591-2019.