Psychiatry and Clinical Neurosciences

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Comorbid substance use disorder in schizophrenia: A selective overview of neurobiological and cognitive underpinnings
Psychiatry and Clinical Neurosciences - Tập 67 Số 6 - Trang 367-383 - 2013
Patrizia Thoma, Irene Daum
Although individuals with schizophrenia show a lifetime prevalence of 50% for suffering from a comorbid substance use disorder, substance abuse usually represents an exclusion criterion for studies on schizophrenia. This implies that surprisingly little is known about a large group of patients who are particularly difficult to treat. The aim of the present work is to provide a brief and no...... hiện toàn bộ
Regional cerebral blood flow abnormalities in late‐life depression:Relation to refractoriness and chronification
Psychiatry and Clinical Neurosciences - Tập 52 Số 1 - Trang 97-105 - 1998
Shuichi Awata, Hiroshi Itoh, Michiko Konno, Shuichi Ono, Ryuta Kawashima, Hiroshi Fukuda, M Sato
Abstract We examined patterns of regional cerebral blood flow (rCBF) abnormalities in 18 patients with major depressive disorder in late life using single photon emission computed tomography (SPECT) and (99mTc‐hexamethyl‐propylenamine oxime (99mTc‐HMPAO). Compared with 13 age‐matched controls, relative rCBF was significantly ...... hiện toàn bộ
Glutamate hypothesis in schizophrenia
Psychiatry and Clinical Neurosciences - Tập 73 Số 5 - Trang 204-215 - 2019
Yota Uno, Joseph T. Coyle
Schizophrenia is a chronic and severe psychiatric disorder that has profound impact on an individual’s life and on society. Thus, developing more effective therapeutic interventions is essential. Over the past quarter‐century, an abundance of evidence from pharmacologic challenges, post‐mortem studies, brain imaging, and genetic studies supports the role of glutamatergic dysregulation in t...... hiện toàn bộ
Brain‐derived neurotrophic factor as a biomarker for mood disorders: An historical overview and future directions
Psychiatry and Clinical Neurosciences - Tập 64 Số 4 - Trang 341-357 - 2010
Kenji Hashimoto
Mood disorders, such as major depressive disorder (MDD) and bipolar disorder (BPD), are the most prevalent psychiatric conditions, and are also among the most severe and debilitating. However, the precise neurobiology underlying these disorders is currently unknown. One way to combat these disorders is to discover novel biomarkers for them. The development of such biomarkers will aid both ...... hiện toàn bộ
Validity of the Japanese version of the REM Sleep Behavior Disorder (RBD) Screening Questionnaire for detecting probable RBD in the general population
Psychiatry and Clinical Neurosciences - Tập 69 Số 8 - Trang 477-482 - 2015
Takashi Nomura, Yuichi Inoue, Tatsuo Kagimura, Masayoshi Kusumi, Kenji Nakashima
AimsIn order to evaluate the validity of the REM Sleep Behavior Disorder (RBD) Screening Questionnaire (RBDSQ...... hiện toàn bộ
Prevalence and incidence of schizophrenia among national health insurance enrollees in Taiwan, 1996–2001
Psychiatry and Clinical Neurosciences - Tập 58 Số 6 - Trang 611-618 - 2004
I‐Chia Chien, YIING‐JENQ CHOU, Ching‐Heng Lin, Shin‐Huey Bih, Pesus Chou, HONG‐JEN CHANG
Abstract  As many as 96% of all residents of Taiwan have been enrolled in the National Health Insurance (NHI) program since 1996. The NHI database was used to examine the prevalence and incidence of schizoprenia. The National Health Research Institute provided a database of 200 432 random subjects, about 1% of the population, for study. By means of exclusion criteria...... hiện toàn bộ
Prevalence of insomnia in various psychiatric diagnostic categories
Psychiatry and Clinical Neurosciences - Tập 56 Số 3 - Trang 239-240 - 2002
YASUKO OKUJI, Masato Matsuura, Naoko Kawasaki, SINOBU KOMETANI, TAKAKO SHIMOYAMA, Mitsugu Sato, K. Oga, Koichi Abe
Abstract Sixty percent of 536 new referrals to a psychiatric clinic at a general hospital complained of insomnia. Prevalence was high in all psychiatric categories, especially in physiologic disorders, somatoform disorders and mood disorders, followed by epilepsy. Complaints of difficulty in falling asleep were high in the physiologic and somatoform disorder groups. ...... hiện toàn bộ
Frontal and cingulate gray matter volume reduction in heroin dependence: Optimized voxel‐based morphometry
Psychiatry and Clinical Neurosciences - Tập 63 Số 4 - Trang 563-568 - 2009
Haihong Liu, Yihui Hao, Yoshio Kaneko, Xuan Ouyang, Yan Zhang, Lin Xu, Zhimin Xue, Zhening Liu
Aims:  Repeated exposure to heroin, a typical opiate, causes neuronal adaptation and may result in anatomical changes in specific brain regions, particularly the frontal and limbic cortices. The volume changes of gray matter (GM) of these brain regions, however, have not been identified in heroin addiction.Methods:  Using struc...... hiện toàn bộ
Resting state default‐mode network connectivity in early depression using a seed region‐of‐interest analysis: Decreased connectivity with caudate nucleus
Psychiatry and Clinical Neurosciences - Tập 63 Số 6 - Trang 754-761 - 2009
Robyn Bluhm, Peter Williamson, Ruth A. Lanius, Jean Théberge, Maria Densmore, Robert Bartha, Richard W. J. Neufeld, Elizabeth Osuch
Aim:  Reports on resting brain activity in healthy controls have described a default‐mode network (DMN) and important differences in DMN connectivity have emerged for several psychiatric conditions. No study to date, however, has investigated resting‐state DMN in relatively early depression before years of medication treatment. The objective of the present study was,...... hiện toàn bộ
Cross‐cultural adaptation and psychometric properties of the Social Capital Questionnaire for Adolescent Students among preadolescents and adolescents in Japan
Psychiatry and Clinical Neurosciences - Tập 73 Số 9 - Trang 601-602 - 2019
Tomoya Hirota, Masaki Adachi, Michio Takahashi, Kazuhiko Nakamura
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