Pituitary
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Systemic illness
Pituitary - Tập 11 - Trang 187-207 - 2008
Systemic illnesses are associated with alterations in the hypothalamic–pituitary–peripheral hormone axes, which represent part of the adaptive response to stressful events and may be influenced by type and severity of illness and/or pharmacological therapy. The pituitary gland responds to an acute stressful event with two secretory patterns: adrenocorticotropin (ACTH), prolactin (PRL) and growth h......
Endoscopic endonasal approach for pituitary adenoma: surgical complications in 301 patients
Pituitary - Tập 14 - Trang 174-183 - 2010
The authors investigate the complications of transnasal transsphenoidal endoscopic surgery in the treatment of 301 patients with pituitary adenomas. A retrospective analysis of complications in 301 patients submitted to transsphenoidal transnasal endoscopic surgery at the General Hospital of Fortaleza, Brazil between January 1998 and December 2009. The complications were divided in two groups: ana......
T2-weighted MRI signal intensity as a predictor of hormonal and tumoral responses to somatostatin receptor ligands in acromegaly: a perspective
Pituitary - - 2017
Copeptin response to hypoglycemic stress is linked to prolactin activation in children
Pituitary - - 2020
The physiological role of arginine vasopressin (AVP) in the acute stress response in humans and especially in children is unclear. The aim of this study was to explore the interaction between copeptin, a well-established surrogate marker of AVP release, and anterior pituitary hormone activation in response to acute hypoglycemic stress in children and adolescents. We conducted an exploratory single......
Hypothalamic pituitary abnormalities in tubercular meningitis at the time of diagnosis
Pituitary - Tập 13 - Trang 304-310 - 2010
Tubercular meningitis (TBM) is the most dreaded form of extra pulmonary tuberculosis associated with high morbidity and mortality. Various hypothalamic pituitary hormonal abnormalities have been reported to occur years after recovery from disease but there are no systematic studies in the literature to evaluate the pituitary hypothalamic dysfunction in patients with TBM at the time of presentation......
Cushing's Syndrome: Historical Aspects
Pituitary - Tập 3 - Trang 97-104 - 2000
A brief overview of the most important steps leading to our present knowledge of hypercorticism is given. The adrenals were described in 1563 and the pituitary had been known since Antiquity. Until Addison's description of adrenal insufficiency in 1855 virtually nothing was known of their function. Cushing in 1912 described his famous patient with hypercorticism but assumed it to be a polyglandula......
Thyrotropin-secreting pituitary adenomas: a systematic review and meta-analysis of postoperative outcomes and management
Pituitary - Tập 22 - Trang 79-88 - 2018
TSH-secreting pituitary adenomas are rare pituitary tumors. An efficient treatment is essential to limit the mortality and morbidity in untreated patients. The aim of this study is to summarize the evidence about the postoperative outcomes and management of this rare pathology. A systematic search and meta-analysis of surgical series was performed. Our analysis included 23 articles (536 patients).......
Dramatic Volume Reduction of a Large GH/TSH Secreting Pituitary Tumor with Short Term Octreotide Therapy
Pituitary - Tập 8 - Trang 89-91 - 2005
A case is presented of a huge GH/TSH secreting tumor and marked volumetric reduction in size with only one week of Octreotide therapy. To our knowledge, this is the first reported case of such a dramatic volumetric response to short-term Octreotide therapy.
Pegvisomant-primed glucagon stimulation test in assessing GH reserve and GH/IGF kinetics in adults suspected of GH deficiency
Pituitary - Tập 19 Số 1 - Trang 65-74 - 2016
Preoperative assessment for pituitary surgery
Pituitary - Tập 11 - Trang 347-351 - 2008
Evaluation of pituitary function is essential before pituitary surgery. In hyperprolactinaemic patients with a pituitary macrolesion, tumoral secretion of prolactin must be distinguished from ‘disconnection’ hyperprolactinaemia; serum prolactin >200 mcg/l is virtually diagnostic of a macroprolactinoma whereas levels <80 mcg/l usually indicate ‘disconnection’. The prolactin ‘hook effect’ should be ......
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