A randomized, double-blind, placebo controlled safety, tolerability, and pharmacokinetic dose escalation study of a gentamicin vancomycin gel in patients undergoing colorectal surgeryPerioperative Medicine - Tập 5 - Trang 1-8 - 2016
Elliott Bennett-Guerrero, Harold S. Minkowitz, Alvaro M. Segura-Vasi, Jorge E. Marcet, Jennifer A. White, G Ralph Corey, Kent S. Allenby
Despite numerous interventions promulgated by the Surgical Care Improve Project
(SCIP) and other organizations, surgical site infection (SSI) continues to be a
significant medical problem. DFA-02 is a novel bioresorbable modified-release
gel consisting of both gentamicin (16.8 mg/mL) and vancomycin (18.8 mg/mL) to be
applied during surgical incision closure for the prevention of SSIs. The
followin... hiện toàn bộ
Intravenous lidocaine infusion as a component of multimodal analgesia for colorectal surgery—measurement of plasma levelsPerioperative Medicine - Tập 8 - Trang 1-5 - 2019
E. Greenwood, S. Nimmo, H. Paterson, N. Homer, I. Foo
Growing evidence suggests that intravenous lidocaine as a component of
multimodal analgesia improves recovery after major colorectal surgery. There is
little published data regarding ideal dosing and target plasma concentration in
this context, and we wanted to establish our dosing schedule was safe by
measuring blood levels of lidocaine. We measured the plasma lidocaine
concentration of 32 patien... hiện toàn bộ
Focused cardiac ultrasound in preoperative assessment: the perioperative provider’s new stethoscope?Perioperative Medicine - Tập 8 - Trang 1-8 - 2019
Tara Lenk, John Whittle, Timothy E. Miller, David G. A. Williams, Yuriy S. Bronshteyn
Focused cardiac ultrasound (FoCUS)—a simplified, qualitative version of
echocardiography—is a well-established tool in the armamentarium of critical
care and emergency medicine. This review explores the extent to which FoCUS
could also be used to enhance the preoperative physical examination to better
utilise resources and identify those who would benefit most from detailed
echocardiography prior ... hiện toàn bộ
Standard coagulation assays alone are not sufficient to exclude surgically relevant rivaroxaban plasma concentrationsPerioperative Medicine - Tập 8 Số 1 - 2019
Alexander Kaserer, Andreas Schedler, Burkhardt Seifert, Donat R. Spahn, Jan‐Dirk Studt, Philipp Stein
Abstract Background While mainly larger hospitals have introduced routine
anti-Xa assays for rivaroxaban (RXA), these are not readily available to smaller
hospitals often relying on routine coagulation tests such as prothrombin time
(PT) and activated partial thromboplastin time (aPTT). The aim of our study was
to investigate the effect of RXA plasma concentration on the standard
coagulation tests... hiện toàn bộ
How fast can glucose be infused in the perioperative setting?Perioperative Medicine - Tập 5 - Trang 1-8 - 2016
Robert G. Hahn
How the initial infusion rate of glucose solution should be set to avoid
hyperglycemia in the perioperative setting is unclear. Computer simulations were
performed based on data from seven studies where the kinetics of glucose was
calculated using a one-compartment model. Glucose had been infused intravenously
on 44 occasions to volunteers and on 256 occasions to surgical patients at
various stage... hiện toàn bộ
American Society for Enhanced Recovery (ASER) and Perioperative Quality Initiative (POQI) joint consensus statement on measurement to maintain and improve quality of enhanced recovery pathways for elective colorectal surgeryPerioperative Medicine - Tập 6 - Trang 1-10 - 2017
S. Ramani Moonesinghe, Michael P. W. Grocott, Elliott Bennett-Guerrero, Roberto Bergamaschi, Vijaya Gottumukkala, Thomas J. Hopkins, Stuart McCluskey, Tong J. Gan, Michael Monty G. Mythen, Andrew D. Shaw, Timothy E. Miller
This article sets out a framework for measurement of quality of care relevant to
enhanced recovery pathways (ERPs) in elective colorectal surgery. The proposed
framework is based on established measurement systems and/or theories, and
provides an overview of the different approaches for improving clinical
monitoring, and enhancing quality improvement or research in varied settings
with different l... hiện toàn bộ
Magnitude of early postoperative hypoxemia and its associated factors among adult patients who undergo emergency surgery under general anesthesia at Jimma Medical Center, Jimma, Southwest Ethiopia, 2021: a prospective observational studyPerioperative Medicine - Tập 12 - Trang 1-10 - 2023
Mitiku Berhanu, Negashu Dadi, Berhanu Mengistu, Zemenu Muluken, Ashenafi Tolesa, Tajera Tageza, Megersa Kalbesa, Gezahegn Tesfaye, Belay Zawdie
Emergency surgical procedures involve considerable risks. Among these, early
postoperative hypoxemia (EPH) is a frequent anesthetic complication in the
post-anesthetic care unit (PACU). There is a great concern for EPH among health
professionals, specifically, those providing emergency surgery during the
nighttime. This raised anesthesia-ended time-related risk of EPH question. Thus,
this study ai... hiện toàn bộ
Huashan perioperative nursing program for stroke patients undergoing contralateral seventh cervical nerve transferPerioperative Medicine - Tập 11 - Trang 1-7 - 2022
Fan Su, Ye Xu, Xiaoqian Wang, Yiqun Zhou, Wendong Xu, Yaojin Zhang, Ying Liu
A previous investigation regarding contralateral seventh cervical nerve transfer
(CC7) revealed a novel and effective approach to improve arm function in
patients with chronic spastic paralysis. The patients who underwent both CC7 and
standard rehabilitation showed greater functional improvements and spasticity
reductions than patients in the control group, who underwent rehabilitation
only. Addit... hiện toàn bộ