Pediatric Allergy and Immunology

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Cytokine production, activation marker, and skin homing receptor in children with atopic dermatitis and bronchial asthma
Pediatric Allergy and Immunology - Tập 17 Số 3 - Trang 166-174 - 2006
C. Antúnez, Marı́a José Torres, Cristobalina Mayorga, José Luís Corzo, Antonio Jurado, Luis F. Santamaria‐Babí, Ángel Vera, Miguel Blanca
T cells are known to develop a critical role in the pathogenesis of atopic dermatitis (AD) and bronchial asthma. T cells involved in AD express the skin homing receptor CLA, but no lung homing receptor has been identified in bronchial asthma. We compared different cell markers and the cytokine production in T cells from children with AD or bronchial asthma. We studied the involvement of CL...... hiện toàn bộ
High prevalence and young onset of allergic rhinitis in children with bronchial asthma
Pediatric Allergy and Immunology - Tập 19 Số 6 - Trang 517-522 - 2008
Sawako Masuda, Takao Fujisawa, Hajime Katsumata, Jun Atsuta, Kosei Iguchi
Bronchial asthma and allergic rhinitis often co‐exist, and rhinitis is a major risk factor for the development of asthma. However, the reported incidence of allergic rhinitis in asthmatic children varies widely. The aim of this study was to elucidate the incidence of allergic rhinitis, the onset age of chronic upper and lower airway symptoms, and the correlation of these two symptoms in as...... hiện toàn bộ
Endotoxin exposure and symptoms in asthmatic children
Pediatric Allergy and Immunology - Tập 8 Số 3 - Trang 121-126 - 1997
M C Rizzo, Charles K. Naspitz, Enrique Fernández‐Caldas, Richard F. Lockey, I Mimica, Dirceu Solé
Endotoxins (ET) are pro‐innammatory substances present in hou.sc dust which may increase non‐specific bronchial reactivity in asthmatic patients. Endotoxins (EU/g) and Der p I levels were compared in the homes often asthmatic and ten control children, aged 6‐16 years, living in Sao Paulo, Brazil. The houses were visited once a month from February 1993 lo February 1994 and dust samples were...... hiện toàn bộ
EAACI Molecular Allergology User's Guide
Pediatric Allergy and Immunology - Tập 27 Số S23 - Trang 1-250 - 2016
Paolo Maria Matricardi, Jörg Kleine‐Tebbe, Hans Jürgen Hoffmann, Rudolf Valenta, Christiane Hilger, Stephanie Hofmaier, Rob C. Aalberse, Ioana Agache, R. Asero, Barbara Ballmer‐Weber, Domingo Barber, Kirsten Beyer, Tilo Biedermann, Maria Beatrice Bilò, Simon Blank, Barbara Bohle, Philipp P. Bosshard, Heimo Breiteneder, Helen A. Brough, Luis Caraballo, Jean‐Christoph Caubet, Reto Crameri, Janet M. Davies, Nikolaos Douladiris, Motohiro Ebisawa, Philippe Eigenmann, Montserrat Fernández‐Rivas, Fátima Ferreira, Gabriele Gadermaier, Martin Glatz, Robert G. Hamilton, T. Hawranek, Peter W. Hellings, Karin Hoffmann‐Sommergruber, Thilo Jakob, Uta Jappe, Marek Jutel, Sandip D. Kamath, Edward F. Knol, Peter Korošec, Annette Kuehn, Gideon Lack, Andreas L. Lopata, Mika J. Mäkelä, M. Morisset, Verena Niederberger, Anna Nowak‐Węgrzyn, Nikolaos G. Papadopoulos, Elide A. Pastorello, G. Pauli, Thomas A.E. Platts‐Mills, Daniela Posa, Lars K. Poulsen, Monika Raulf, J. Sastre, Enrico Scala, Johannes Martin Schmid, Peter Schmid‐Grendelmeier, Marianne van Hage, Ronald van Ree, Stefan Vieths, Richard W. Weber, Magnus Wickman, Antonella Muraro, Markus Ollert
AbstractThe availability of allergen molecules (‘components’) from several protein families has advanced our understanding of immunoglobulin E (IgE)‐mediated responses and enabled ‘component‐resolved diagnosis’ (CRD). The European Academy of Allergy and Clinical Immunology ( hiện toàn bộ
Is it possible to make a diagnosis of raw, heated, and baked egg allergy in children using cutoffs? A systematic review
Pediatric Allergy and Immunology - Tập 26 Số 6 - Trang 509-521 - 2015
Mauro Calvani, Stefania Arasi, Annamaria Bianchi, Davide Caimmi, Barbara Cuomo, Arianna Dondi, Giovanni Cosimo Indirli, Stefania La Grutta, Valentina Panetta, Maria Carmen Verga
AbstractThe diagnosis of IgE‐mediated egg allergy lies both on a compatible clinical history and on the results of skin prick tests (SPTs) and IgEs levels. Both tests have good sensitivity but low specificity. For this reason, oral food challenge ( hiện toàn bộ
Matrix effect on baked egg tolerance in children with IgE‐mediated hen's egg allergy
Pediatric Allergy and Immunology - Tập 27 Số 5 - Trang 465-470 - 2016
Stefano Miceli Sopo, Monica Greco, Barbara Cuomo, Annamaria Bianchi, Lucia Liotti, Serena Monaco, Iride Dello Iacono
AbstractBackgroundChildren with IgE‐mediated hen's egg allergy (IgE‐HEA) often tolerate baked egg within a wheat matrix.ObjectiveTo evaluate the influence of wheat matrix and the effects of little standardiz...... hiện toàn bộ
Skin testing with raw egg does not predict tolerance to baked egg in egg‐allergic children
Pediatric Allergy and Immunology - Tập 25 Số 7 - Trang 657-661 - 2014
Paul Turner, Kartik Kumar, Adam T. Fox
AbstractBackgroundMost children with egg allergy tolerate egg in baked foods, such as cake, but tolerance cannot be predicted with conventional allergy testing. We hypothesized that the skin prick test (SPT) wheal to unprocessed raw egg might predict tolerance of baked ...... hiện toàn bộ
Safety of food challenges to extensively heated egg in egg‐allergic children: a prospective cohort study
Pediatric Allergy and Immunology - Tập 24 Số 5 - Trang 450-455 - 2013
Paul Turner, Sam Mehr, Preeti Joshi, John Tan, Melanie Wong, Alyson Kakakios, Dianne E. Campbell
AbstractBackgroundMany children with IgE‐mediated allergy to egg can tolerate egg in baked foods. However, the clinical characteristics and severity of reactions of egg‐allergic children who react to baked egg at open food challenge ( hiện toàn bộ
Pre‐natal sensitization in humans
Pediatric Allergy and Immunology - Tập 11 Số s13 - Trang 6-8 - 2000
J. O. Warner, Catherine A. Jones, Sally Kilburn, Gillian Vance, Jill A. Warner
Allergy has a very strong hereditary component but even in identical twins, concordance for the development of allergic disease can be as low as 50%. This suggests that there is a very strong environmental influence on manifestations of sensitization. To what extent environment might have an influence on the ontogeny of sensitization antenatally has hitherto not been a focus of much resear...... hiện toàn bộ
Primary sensitization to inhalant allergens
Pediatric Allergy and Immunology - Tập 11 Số s13 - Trang 9-11 - 2000
Claudia Macaubas, Susan L. Prescott, T. Venaille, Barbara J. Holt, Troy B. Smallacombe, Peter D. Sly, Patrick G. Holt
The neonatal T‐cell system is capable of responding to allergens at birth, indicating the occurrence of prenatal sensitization, and the cytokine profile of these responses is skewed towards the Th‐2 type. This response is further modified by postnatal exposure to different types of allergens. In relation to inhalant allergen (employed by HDM) the low level fetal Th‐2 responses in non‐atopi...... hiện toàn bộ
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