Pediatric Allergy and Immunology
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EXPRESSION OF CONCERN: The effects of melatonin administration on disease severity and sleep quality in children with atopic dermatitis: A randomized, double‐blinded, placebo‐controlled trial
Pediatric Allergy and Immunology - Tập 29 Số 8 - Trang 834-840 - 2018
AbstractBackgroundThe aim of this clinical trial was to determine the effects of
melatonin administration on disease severity and sleep quality in children
diagnosed with atopic dermatitis (AD).MethodsThis randomized, double‐blinded,
placebo‐controlled trial was conducted by recruiting 70 patients, aged
6‐12 years, who had been diagnosed with AD. Study participants were randomly
allocated into two...
Fecal microbiome signatures are different in food‐allergic children compared to siblings and healthy children
Pediatric Allergy and Immunology - Tập 29 Số 5 - Trang 545-554 - 2018
AbstractBackgroundIntestinal microbes have been shown to influence
predisposition to atopic disease, including food allergy. The intestinal
microbiome of food‐allergic children may differ in significant ways from
genetically similar non‐allergic children and age‐matched controls. The aim was
to characterize fecal microbiomes to identify taxa that may influence the
expression of food allergy.Method...
High prevalence and young onset of allergic rhinitis in children with bronchial asthma
Pediatric Allergy and Immunology - Tập 19 Số 6 - Trang 517-522 - 2008
Bronchial asthma and allergic rhinitis often co‐exist, and rhinitis is a major
risk factor for the development of asthma. However, the reported incidence of
allergic rhinitis in asthmatic children varies widely. The aim of this study was
to elucidate the incidence of allergic rhinitis, the onset age of chronic upper
and lower airway symptoms, and the correlation of these two symptoms in
asthmatic ...
Pre‐natal sensitization in humans
Pediatric Allergy and Immunology - Tập 11 Số s13 - Trang 6-8 - 2000
Allergy has a very strong hereditary component but even in identical twins,
concordance for the development of allergic disease can be as low as 50%. This
suggests that there is a very strong environmental influence on manifestations
of sensitization. To what extent environment might have an influence on the
ontogeny of sensitization antenatally has hitherto not been a focus of much
research. Howe...
Primary sensitization to inhalant allergens
Pediatric Allergy and Immunology - Tập 11 Số s13 - Trang 9-11 - 2000
The neonatal T‐cell system is capable of responding to allergens at birth,
indicating the occurrence of prenatal sensitization, and the cytokine profile of
these responses is skewed towards the Th‐2 type. This response is further
modified by postnatal exposure to different types of allergens. In relation to
inhalant allergen (employed by HDM) the low level fetal Th‐2 responses in
non‐atopics appea...
Quantification of IgE antibodies simplifies the classification of allergic diseases in 4‐year‐old children. A report from the prospective birth cohort study – BAMSE
Pediatric Allergy and Immunology - Tập 14 Số 6 - Trang 441-447 - 2003
Allergic diseases are common among small children, but it is still unclear how
immunoglobulin E (IgE) antibodies to ambient allergens are distributed in a
population‐based prospective material of children at 4 years of age. The study
is based on 75% (n = 4089) of all eligible children from northern Stockholm,
born between 1994 and 1996 in pre‐defined geographical areas. Data on exposure
and outcom...
Cytokine production, activation marker, and skin homing receptor in children with atopic dermatitis and bronchial asthma
Pediatric Allergy and Immunology - Tập 17 Số 3 - Trang 166-174 - 2006
T cells are known to develop a critical role in the pathogenesis of atopic
dermatitis (AD) and bronchial asthma. T cells involved in AD express the skin
homing receptor CLA, but no lung homing receptor has been identified in
bronchial asthma. We compared different cell markers and the cytokine production
in T cells from children with AD or bronchial asthma. We studied the involvement
of CLA+ and C...
Diagnostic value of exhaled nitric oxide in childhood asthma and allergy
Pediatric Allergy and Immunology - Tập 21 Số 1-Part-II - 2010
Sachs‐Olsen C, Lødrup Carlsen KC, Mowinckel P, Håland G, Devulapalli CS,
Munthe‐Kaas MC, Carlsen K‐H. Diagnostic value of exhaled nitric oxide in
childhood asthma and allergy.
Pediatr Allergy Immunol 2010: 21: e213–e221.
©
2010 John Wiley & Sons A/SFractional exhaled nitric oxide (FENO) has been
proposed as a diagnostic test of asthma. We aimed to investigate in a population
based birth cohort of ...
The compliance and burden of treatment with the epinephrine auto‐injector in food‐allergic adolescents
Pediatric Allergy and Immunology - Tập 27 Số 1 - Trang 28-34 - 2016
AbstractBackgroundFood‐allergic patients at high risk of potential fatal
anaphylaxis should carry an epinephrine auto‐injector (EAI) at all times. This
treatment may be perceived as burdensome and this may affect compliance and
health‐related quality of life (HRQL). The aims of the study were (1) to
determine the burden of treatment (BoT) of an EAI, (2) to examine the
relationship between this bur...
Why do few food‐allergic adolescents treat anaphylaxis with adrenaline? – reviewing a pressing issue
Pediatric Allergy and Immunology - Tập 24 Số 3 - Trang 222-229 - 2013
AbstractFood allergic adolescents are at higher risk of fatal anaphylaxis than
other children. Both allergen avoidance and maintaining access to adrenaline
auto‐injectors (AAI) are key goals in effective food allergy management, for
which written guidance is often supplied. However, adolescents are rarely
sufficiently prepared to use adrenaline during anaphylaxis. It is likely that
further didacti...
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