Pre‐natal sensitization in humans

Pediatric Allergy and Immunology - Tập 11 Số s13 - Trang 6-8 - 2000
J. O. Warner1, Catherine A. Jones2, Sally Kilburn2, Gillian Vance2, Jill A. Warner2
1Child Health, University of Southampton, Southampton General Hospital, UK.
2Child Health. University of Southampton, Southampton General Hospital, Southampton, UK

Tóm tắt

Allergy has a very strong hereditary component but even in identical twins, concordance for the development of allergic disease can be as low as 50%. This suggests that there is a very strong environmental influence on manifestations of sensitization. To what extent environment might have an influence on the ontogeny of sensitization antenatally has hitherto not been a focus of much research. However, circumstantial evidence suggests that this may be important.

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