Oxidative Medicine and Cellular Longevity
SCOPUS (2008-2024)
1942-0994
1942-0900
Mỹ
Cơ quản chủ quản: Hindawi Publishing Corporation
Lĩnh vực:
Cell BiologyAgingMedicine (miscellaneous)Biochemistry
Các bài báo tiêu biểu
Polyphenol thực vật như chất chống oxy hoá trong dinh dưỡng và bệnh tật ở con người Dịch bởi AI
Tập 2 Số 5 - Trang 270-278 - 2009
Polyphenol là các chất chuyển hóa thứ cấp của thực vật và thường tham gia vào
việc bảo vệ chống lại tia cực tím hoặc sự xâm nhập của các tác nhân gây bệnh.
Trong thập kỷ qua, đã có nhiều quan tâm về tiềm năng lợi ích sức khỏe từ
polyphenol thực vật trong chế độ ăn uống như một chất chống oxy hoá. Các nghiên
cứu dịch tễ học và phân tích tổng hợp liên quan mạnh mẽ đến việc tiêu thụ lâu
dài các chế đ...
#polyphenol thực vật #chất chống oxy hóa #sức khỏe con người #ung thư #bệnh tim mạch #tiểu đường #loãng xương #bệnh thoái hóa thần kinh #chất chuyển hóa thứ cấp #bảo vệ tế bào.
Exogenous Antioxidants—Double‐Edged Swords in Cellular Redox State: Health Beneficial Effects at Physiologic Doses versus Deleterious Effects at High Doses
Tập 3 Số 4 - Trang 228-237 - 2010
The balance between oxidation and antioxidation is believed to be critical in
maintaining healthy biological systems. Under physiological conditions, the
human antioxidative defense system including e.g., superoxide dismutase (SOD),
catalase (CAT), glutathione peroxidase (GPx), glutathione (GSH) and others,
allows the elimination of excess reactive oxygen species (ROS) including, among
others supe...
Does the Interdependence between Oxidative Stress and Inflammation Explain the Antioxidant Paradox?
Tập 2016 Số 1 - 2016
Oxidative stress has been implicated in many chronic diseases. However,
antioxidant trials are so far largely unsuccessful as a preventive or curative
measure. Chronic low‐grade inflammatory process, on the other hand, plays a
central role in the pathogenesis of a number of chronic diseases. Oxidative
stress and inflammation are closely related pathophysiological processes, one of
which can be eas...
Honey, Propolis, and Royal Jelly: A Comprehensive Review of Their Biological Actions and Health Benefits
Tập 2017 Số 1 - 2017
Background. There are several health benefits that honeybee products such as
honey, propolis, and royal jelly claim toward various types of diseases in
addition to being food. Scope and Approach. In this paper, the effects of honey,
propolis, and royal jelly on different metabolic diseases, cancers, and other
diseases have been reviewed. The modes of actions of these products have also
been illust...
ROS Generation and Antioxidant Defense Systems in Normal and Malignant Cells
Tập 2019 - Trang 1-17 - 2019
Reactive oxygen species (ROS) are by-products of normal cell activity. They are
produced in many cellular compartments and play a major role in signaling
pathways. Overproduction of ROS is associated with the development of various
human diseases (including cancer, cardiovascular, neurodegenerative, and
metabolic disorders), inflammation, and aging. Tumors continuously generate ROS
at increased le...
Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More
Tập 2016 Số 1 - 2016
Increasing interest has recently focused on determining whether several natural
compounds, collectively referred to as nutraceuticals, may exert neuroprotective
actions in the developing, adult, and aging nervous system. Quercetin, a
polyphenol widely present in nature, has received the most attention in this
regard. Several studies in vitro, in experimental animals and in humans, have
provided su...
The Essential Element Manganese, Oxidative Stress, and Metabolic Diseases: Links and Interactions
Tập 2018 Số 1 - 2018
Manganese (Mn) is an essential element that is involved in the synthesis and
activation of many enzymes and in the regulation of the metabolism of glucose
and lipids in humans. In addition, Mn is one of the required components for Mn
superoxide dismutase (MnSOD) that is mainly responsible for scavenging reactive
oxygen species (ROS) in mitochondrial oxidative stress. Both Mn deficiency and
intoxic...
Advanced Glycation end Products, Oxidative Stress and Diabetic Nephropathy
Tập 3 Số 2 - Trang 101-108 - 2010
About 246 million people worldwide had diabetes in 2007. The global figure of
people with diabetes is projected to increase to 370 million in 2030. As the
prevalence of diabetes has risen to epidemic proportions worldwide, diabetic
nephropathy has become one of the most challenging health problems. Therapeutic
options such as strict blood glucose and blood pressure controls are effective
for preve...
Molecular Events Linking Oxidative Stress and Inflammation to Insulin Resistance andβ-Cell Dysfunction
Tập 2015 - Trang 1-15 - 2015
The prevalence of diabetes mellitus (DM) is increasing worldwide, a consequence
of the alarming rise in obesity and metabolic syndrome (MetS). Oxidative stress
and inflammation are key physiological and pathological events linking obesity,
insulin resistance, and the progression of type 2 DM (T2DM). Unresolved
inflammation alongside a “glucolipotoxic” environment of the pancreatic islets,
in insul...