Oxford University Press (OUP)

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Genomic analyses reveal FAM84B and the NOTCH pathway are associated with the progression of esophageal squamous cell carcinoma
Oxford University Press (OUP) - Tập 5 - Trang 1-14 - 2016
Caixia Cheng, Heyang Cui, Ling Zhang, Zhiwu Jia, Bin Song, Fang Wang, Yaoping Li, Jing Liu, Pengzhou Kong, Ruyi Shi, Yanghui Bi, Bin Yang, Juan Wang, Zhenxiang Zhao, Yanyan Zhang, Xiaoling Hu, Jie Yang, Chanting He, Zhiping Zhao, Jinfen Wang, Yanfeng Xi, Enwei Xu, Guodong Li, Shiping Guo, Yunqing Chen, Xiaofeng Yang, Xing Chen, Jianfang Liang, Jiansheng Guo, Xiaolong Cheng, Chuangui Wang, Qimin Zhan, Yongping Cui
Esophageal squamous cell carcinoma (ESCC) is the sixth most lethal cancer worldwide and the fourth most lethal cancer in China. Genomic characterization of tumors, particularly those of different stages, is likely to reveal additional oncogenic mechanisms. Although copy number alterations and somatic point mutations associated with the development of ESCC have been identified by array-based techno...... hiện toàn bộ
The 3,000 rice genomes project
Oxford University Press (OUP) - Tập 3 - Trang 1-6 - 2014
Rice, Oryza sativa L., is the staple food for half the world’s population. By 2030, the production of rice must increase by at least 25% in order to keep up with global population growth and demand. Accelerated genetic gains in rice improvement are needed to mitigate the effects of climate change and loss of arable land, as well as to ensure a stable global food supply. We resequenced a core colle...... hiện toàn bộ
Quantifying the use of bioresources for promoting their sharing in scientific research
Oxford University Press (OUP) - Tập 2 - Trang 1-8 - 2013
Laurence Mabile, Raymond Dalgleish, Gudmundur A Thorisson, Mylène Deschênes, Robert Hewitt, Jane Carpenter, Elena Bravo, Mirella Filocamo, Pierre Antoine Gourraud, Jennifer R Harris, Paul Hofman, Francine Kauffmann, Maria Angeles Muñoz-Fernàndez, Markus Pasterk, Anne Cambon-Thomsen
An increasing portion of biomedical research relies on the use of biobanks and databases. Sharing of such resources is essential for optimizing knowledge production. A major obstacle for sharing bioresources is the lack of recognition for the efforts involved in establishing, maintaining and sharing them, due to, in particular, the absence of adequate tools. Increasing demands on biobanks and data...... hiện toàn bộ
Erratum: SOAPdenovo2: an empirically improved memory-efficient short-read de novo assembler
Oxford University Press (OUP) - Tập 4 - Trang 1-1 - 2015
Ruibang Luo, Binghang Liu, Yinlong Xie, Zhenyu Li, Weihua Huang, Jianying Yuan, Guangzhu He, Yanxiang Chen, Qi Pan, Yunjie Liu, Jingbo Tang, Gengxiong Wu, Hao Zhang, Yujian Shi, Yong Liu, Chang Yu, Bo Wang, Yao Lu, Changlei Han, David W. Cheung, Siu-Ming Yiu, Shaoliang Peng, Zhu Xiaoqian, Guangming Liu, Xiangke Liao, Yingrui Li, Huanming Yang, Jian Wang, Tak-Wah Lam, Jun Wang
Metabolome of human gut microbiome is predictive of host dysbiosis
Oxford University Press (OUP) - Tập 4 Số 1 - 2015
Peter E. Larsen, Yang Dai
Building a multi-scaled geospatial temporal ecology database from disparate data sources: fostering open science and data reuse
Oxford University Press (OUP) - Tập 4 - Trang 1-15 - 2015
Patricia A. Soranno, Edward G. Bissell, Kendra S. Cheruvelil, Samuel T. Christel, Sarah M. Collins, C. Emi Fergus, Christopher T. Filstrup, Jean-Francois Lapierre, Noah R. Lottig, Samantha K. Oliver, Caren E. Scott, Nicole J. Smith, Scott Stopyak, Shuai Yuan, Mary Tate Bremigan, John A. Downing, Corinna Gries, Emily N. Henry, Nick K. Skaff, Emily H. Stanley, Craig A. Stow, Pang-Ning Tan, Tyler Wagner, Katherine E. Webster
Although there are considerable site-based data for individual or groups of ecosystems, these datasets are widely scattered, have different data formats and conventions, and often have limited accessibility. At the broader scale, national datasets exist for a large number of geospatial features of land, water, and air that are needed to fully understand variation among these ecosystems. However, s...... hiện toàn bộ
Whole genome sequence analysis of BT-474 using complete Genomics’ standard and long fragment read technologies
Oxford University Press (OUP) - - 2016
Serban Ciotlos, Qing Mao, Rebecca Yu Zhang, Zhenyu Li, Robert Chin, Natali Gulbahce, Sophie Jia Liu, Radoje Drmanac, Brock A. Peters
Transcriptome sequences spanning key developmental states as a resource for the study of the cestode Schistocephalus solidus, a threespine stickleback parasite
Oxford University Press (OUP) - Tập 5 - Trang 1-9 - 2016
François Olivier Hébert, Stephan Grambauer, Iain Barber, Christian R. Landry, Nadia Aubin-Horth
Schistocephalus solidus is a well-established model organism for studying the complex life cycle of cestodes and the mechanisms underlying host-parasite interactions. However, very few large-scale genetic resources for this species are available. We have sequenced and de novo-assembled the transcriptome of S. solidus using tissues from whole worms at three key developme...... hiện toàn bộ
Using optical mapping data for the improvement of vertebrate genome assemblies
Oxford University Press (OUP) - Tập 4 Số 1 - 2015
Kerstin Howe, Jonathan Wood
Gigwa—Genotype investigator for genome-wide analyses
Oxford University Press (OUP) - Tập 5 - Trang 1-9 - 2016
Guilhem Sempéré, Florian Philippe, Alexis Dereeper, Manuel Ruiz, Gautier Sarah, Pierre Larmande
Exploring the structure of genomes and analyzing their evolution is essential to understanding the ecological adaptation of organisms. However, with the large amounts of data being produced by next-generation sequencing, computational challenges arise in terms of storage, search, sharing, analysis and visualization. This is particularly true with regards to studies of genomic variation, which are ...... hiện toàn bộ
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