The Treatment of Substance Use Disorders: Recent Developments and New PerspectivesNeuropsychobiology - Tập 81 Số 5 - Trang 451-472 - 2022
Annika Rosenthal, Claudia Ebrahimi, Friederike Wedemeyer, Nina Romanczuk‐Seiferth, Anne Beck
Substance-related disorders are complex psychiatric disorders that are characterized by continued consumption in spite of harmful consequences. Addiction affects various brain networks critically involved in learning, reward, and motivation, as well as inhibitory control. Currently applied therapeutic approaches aim at modification of behavior that ultimately leads to decrease of consumpti...... hiện toàn bộ
Lithium: Still a Cornerstone in the Long-Term Treatment in Bipolar Disorder?Neuropsychobiology - Tập 62 Số 1 - Trang 27-35 - 2010
Alessandra Nivoli, Andréa Murru, Eduard Vieta
<i>Background:</i> Scientific literature considers lithium a key treatment for the acute and long-term management of bipolar disorder (BD). Despite its worldwide clinical use, the effectiveness of lithium has been questioned. The aim of this work is to critically review the available data on randomized controlled trials (RCTs) concerning long-term lithium treatment. <i>Me...... hiện toàn bộ
Lack of Association between Polymorphisms of the Dopamine D<sub>4</sub> Receptor Gene and PersonalityNeuropsychobiology - Tập 47 Số 1 - Trang 52-56 - 2003
Alexander Strobel, Frank M. Spinath, Alois Angleitner, Rainer Riemann, Klaus‐Peter Lesch
Recent studies have suggested a role of two polymorphisms of the dopamine D<sub>4</sub> receptor gene (DRD4 exon III and –521C/T) in the modulation of personality traits such as ‘novelty seeking’ or ‘extraversion’, which are supposed to be modulated by individual differences in dopaminergic function. However, several replication studies have not provided positive findings. The ...... hiện toàn bộ
Chronic Mild Stress (CMS) Revisited: Consistency and Behavioural-Neurobiological Concordance in the Effects of CMSNeuropsychobiology - Tập 52 Số 2 - Trang 90-110 - 2005
Paul Willner
The chronic mild stress (CMS) model of depression has high validity but has in the past been criticized for being difficult to replicate. However, a large number of recent publications have confirmed that CMS causes behavioural changes in rodents that parallel symptoms of depression. This review summarizes studies from over sixty independent research groups that have reported decreases in ...... hiện toàn bộ
Serum Brain-Derived Neurotrophic Factor Levels and Cocaine-Induced Transient Psychotic SymptomsNeuropsychobiology - Tập 68 Số 3 - Trang 146-155 - 2013
Margarida Corominas-Roso, Carlos Roncero, Francisco José Eiroá‐Orosa, Marta Ribasés, Carmen Barral, Constanza Daigre, Nieves Martínez‐Luna, Cristina Sánchez‐Mora, Josep Antoni Ramos‐Quiroga, Miguel Casas
<b><i>Background:</i></b> Cocaine-induced psychosis (CIP) is among the most serious adverse effects of cocaine. Reduced serum brain-derived neurotrophic factor (BDNF) levels have been reported in schizophrenia and psychosis; however, studies assessing the involvement of BDNF in CIP are lacking. <b><i>Methods:</i></b> A total of 22 cocaine-dep...... hiện toàn bộ