The Treatment of Substance Use Disorders: Recent Developments and New Perspectives

Neuropsychobiology - Tập 81 Số 5 - Trang 451-472 - 2022
Annika Rosenthal1, Claudia Ebrahimi1, Friederike Wedemeyer1, Nina Romanczuk‐Seiferth1, Anne Beck1,2
1Department of Psychiatry and Neurosciences|CCM, Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
2Health and Medical University, Campus Potsdam, Faculty of Health, Potsdam, Germany

Tóm tắt

Substance-related disorders are complex psychiatric disorders that are characterized by continued consumption in spite of harmful consequences. Addiction affects various brain networks critically involved in learning, reward, and motivation, as well as inhibitory control. Currently applied therapeutic approaches aim at modification of behavior that ultimately leads to decrease of consumption or abstinence in individuals with substance use disorders. However, traditional treatment methods might benefit from recent neurobiological and cognitive neuroscientific research findings. Novel cognitive-behavioral approaches in the treatment of addictive behavior aim at enhancement of strategies to cope with stressful conditions as well as craving-inducing cues and target erroneous learning mechanisms, including cognitive bias modification, reconsolidation-based interventions, mindfulness-based interventions, virtual-reality-based cue exposure therapy as well as pharmacological augmentation strategies. This review discusses therapeutic strategies that target dysregulated neurocognitive processes associated with the development and maintenance of disordered substance use and may hold promise as effective treatments for substance-related disorders.

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Neuropsychobiology

Tập 81 Số 5

451-472

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