Neuroendocrinology

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NET Blood Transcript Analysis Defines the Crossing of the Clinical Rubicon: When Stable Disease Becomes Progressive
Neuroendocrinology - Tập 104 Số 2 - Trang 170-182 - 2017
Marianne Pavel, Henning Jann, Vikas Prasad, Ignat Drozdov, Irvin M. Modlin, Mark Kidd
Background/Aims: A key issue in gastroenteropancreatic neuroendocrine tumors (GEP-NETs) is early identification and prediction of disease progression. Clinical evaluation and imaging are limited due to the lack of sensitivity and disease indolence. We assessed the NETest as a predictive and prognostic marker of progression in a long-term follow-up study. Methods: GEP-NETs (n = 34) followed...... hiện toàn bộ
Is There an Additional Value of Using Somatostatin Receptor Subtype 2a Immunohistochemistry Compared to Somatostatin Receptor Scintigraphy Uptake in Predicting Gastroenteropancreatic Neuroendocrine Tumor Response?
Neuroendocrinology - Tập 103 Số 5 - Trang 560-566 - 2016
Roxanne C.S. van Adrichem, Kimberly Kamp, Carolien H. M. van Deurzen, Katharina Biermann, Richard A. Feelders, Gaston J H Franssen, Dik J. Kwekkeboom, Leo J. Hofland, Wouter W. de Herder
<b><i>Background and Aims:</i></b> It is unknown whether tumoral somatostatin receptor subtype 2a (sst<sub>2a</sub>) immunohistochemistry (IHC) has additional value compared to somatostatin receptor scintigraphy (SRS) uptake using OctreoScan® in predicting response to peptide receptor radiotherapy using <sup>177</sup>Lu-octreotate (PRRT) in p...... hiện toàn bộ
Identification of a Vasopressin-Neurophysin and of an Oxytocin-Neurophysin in Man
Neuroendocrinology - Tập 13 Số 6 - Trang 371-375 - 1973
J Legros, F. Louis
Impact of Octreotide Long-Acting Release on Tumour Growth Control as a First-Line Treatment in Neuroendocrine Tumours of Pancreatic Origin
Neuroendocrinology - Tập 98 Số 2 - Trang 137-143 - 2013
Henning Jann, Timm Denecke, Martin Koch, Ulrich‐Frank Pape, Bertram Wiedenmann, Marianne Pavel
<b><i>Background:</i></b> Somatostatin analogues (SSA) are widely used in the treatment of patients with functioning and non-functioning neuroendocrine tumours (NET). The aim of our investigation was to evaluate the antiproliferative effect of SSA in patients with pancreatic NET. <b><i>Methods:</i></b> We retrospectively analysed records of 4...... hiện toàn bộ
Vasopressin and Oxytocin Precursors as Model Preprohormones
Neuroendocrinology - Tập 37 Số 3 - Trang 235-239 - 1983
Richard Ivell, Hartwig Schmale, Dietmar Richter
ENETS Consensus Guidelines Update for the Management of Distant Metastatic Disease of Intestinal, Pancreatic, Bronchial Neuroendocrine Neoplasms (NEN) and NEN of Unknown Primary Site
Neuroendocrinology - Tập 103 Số 2 - Trang 172-185 - 2016
Marianne Pavel, Kjell Öberg, Frederico Costa, Jaume Capdevila, D Gross, Réza Kianmanesh, Eric P. Krenning, Ulrich Knigge, Ramón Salazar, Ulrich‐Frank Pape
Somatostatin Receptor Subtypes 2 and 5 Are Associated with Better Survival in Well-Differentiated Endocrine Carcinomas
Neuroendocrinology - Tập 89 Số 2 - Trang 223-230 - 2009
Vito D. Corleto, Massimo Falconi, Francesco Panzuto, Massimo Milione, Ottavia De Luca, Pasquale Perri, Renato Cannizzaro, Cesare Bordi, Paolo Pederzoli, Aldo Scarpa, Gianfranco Delle Fave
The majority of gastroenteropancreatic well-differentiated endocrine carcinomas (WDEC) express somatostatin receptors (SSTR). To correlate the expression of SSTR subtypes by reverse transcriptase-polymerase chain reaction (RT-PCR) with clinicopathological features and survival in a group of WDEC patients, 42 WDEC tissue specimens from 33 patients were analysed. All patients were treated wi...... hiện toàn bộ
The Anterior Periventricular Hypothalamus Is the Site of Somatostatin Inhibition on Its Own Release: An in vitro and Immunocytochemical Study
Neuroendocrinology - Tập 44 Số 2 - Trang 255-259 - 1986
Jacques Epelbaum, Lucia Tapia‐Arancibia, Gérard Alonso, Hélène Astier, Claude Kordon
Physiologically Induced Fos Expression in the Hypothalamo-Hypophyseal System of <i>Xenopus laevis</i>
Neuroendocrinology - Tập 65 Số 6 - Trang 413-422 - 1997
Ruud Ubink, Bruce G. Jenks, Eric W. Roubos
Plasticity in the Melanotrope Neuroendocrine Interface of <i>Xenopus laevis</i>
Neuroendocrinology - Tập 85 Số 3 - Trang 177-185 - 2007
Bruce G. Jenks, Adhanet H. Kidane, Wim J.J.M. Scheenen, Eric W. Roubos
Melanotrope cells of the amphibian pituitary pars intermedia produce α-melanophore-stimulating hormone (α-MSH), a peptide which causes skin darkening during adaptation to a dark background. The secretory activity of the melanotrope of the South African clawed toad <i>Xenopus laevis</i> is regulated by multiple factors, both classical neurotransmitters and neuropeptides from the...... hiện toàn bộ
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