Neurocritical Care
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Prothrombin Complex Concentrate for Emergent Reversal of Intracranial Hemorrhage in Patients with Ventricular Assist Devices
Neurocritical Care - Tập 35 - Trang 506-517 - 2021
Intracranial hemorrhage (ICH) is a devastating complication for patients with ventricular assist devices (VADs). The safety of emergent anticoagulation reversal with four-factor prothrombin complex concentrate (PCC) and optimal timing of anticoagulation resumption are not clear. In addition, lactate dehydrogenase (LDH) is used as a biomarker for thromboembolic risk, but its utility in guiding anti......
Intraventricular Nicardipine for Refractory Cerebral Vasospasm after Subarachnoid Hemorrhage
Neurocritical Care - Tập 8 - Trang 247-252 - 2007
Delayed ischemic deficit from vasospasm is a leading cause of morbidity and mortality after aneurysmal subarachnoid hemorrhage. Although several treatment modalities have been used to reverse the deleterious effects of vasospasm, alternative therapies are needed, as conventional therapies are often ineffective or contraindicated. Intrathecal nicardipine has been suggested for the prevention of vas......
Intravenous Milrinone for Cerebral Vasospasm: Here Comes the Sun?
Neurocritical Care - Tập 36 - Trang 329-330 - 2021
Treatment Outcomes of Heparin-Induced Thrombocytopenia in Subarachnoid Hemorrhage Patients: A 4-Year, Retrospective Single-Center Review
Neurocritical Care - Tập 17 - Trang 177-182 - 2012
The treatment and outcomes of heparin-induced thrombocytopenia (HIT) are not well described in neurosurgery patients. This study reviewed the treatment for HIT in subarachnoid hemorrhage (SAH) patients, and compared outcomes in patients with isolated HIT (iHIT) and HIT with thrombotic syndrome (HITTS). Adult patients with SAH discharged from the University of Illinois Hospital & Health Sciences Sy......
Effect of Interferon-β on Neuroinflammation, Brain Injury and Neurological Outcome After Experimental Subarachnoid Hemorrhage
Neurocritical Care - Tập 18 Số 1 - Trang 96-105 - 2013
Aneurysmal subarachnoid hemorrhage (SAH) has a poor outcome, particularly attributed to progressive injury after the initial incident. Several studies suggest a critical role for inflammation in lesion progression after SAH. Our goal was to test whether treatment with anti-inflammatory interferon-β, which has shown promise as a therapeutic agent in experimental ischaemic stroke, can protect the br......
Hemodynamic, Biochemical, and Ventilatory Parameters are Independently Associated with Outcome after Cardiac Arrest
Neurocritical Care - Tập 29 - Trang 69-76 - 2018
Hypotension, hyperglycemia, dysoxia, and dyscarbia may contribute to reperfusion injury, and each is independently associated with poor outcome (PO) after cardiac arrest. We investigated whether the combined effects of these physiological derangements are associated with cardiac arrest outcomes. This institutional review board-approved retrospective cohort study included consecutive resuscitated c......
Blood Pressure and Spot Sign in Spontaneous Supratentorial Subcortical Intracerebral Hemorrhage
Neurocritical Care - Tập 37 - Trang 246-254 - 2022
Spontaneous intracerebral hemorrhage is a potentially devastating cause of brain injury, often occurring secondary to hypertension. Contrast extravasation on computed tomography angiography (CTA), known as the spot sign, has been shown to predict hematoma expansion and worse outcomes. Although hypertension has been associated with an increased rate of the spot sign being present, the relationship ......
Observations on recent research in neurocritical care
Neurocritical Care - Tập 5 - Trang 79-80 - 2006
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