Prothrombin Complex Concentrate for Emergent Reversal of Intracranial Hemorrhage in Patients with Ventricular Assist DevicesNeurocritical Care - Tập 35 - Trang 506-517 - 2021
Grace Y. Lai, Matthew B. Maas, Christopher R. Leong, Eric M. Liotta, Jonathan D. Rich, Duc T. Pham, Esther E. Vorovich, Andrew M. Naidech, Babak S. Jahromi, Matthew B. Potts
Intracranial hemorrhage (ICH) is a devastating complication for patients with ventricular assist devices (VADs). The safety of emergent anticoagulation reversal with four-factor prothrombin complex concentrate (PCC) and optimal timing of anticoagulation resumption are not clear. In addition, lactate dehydrogenase (LDH) is used as a biomarker for thromboembolic risk, but its utility in guiding anti...... hiện toàn bộ
IV levetiracetam in the management of non-convulsive status epilepticusNeurocritical Care - Tập 7 - Trang 36-39 - 2007
Muhammad U. Farooq, Bharath Naravetla, Arshad Majid, Rishi Gupta, Joseph J. Pysh, Mounzer Y. Kassab
Status epilepticus (SE) is a medical emergency requiring prompt treatment to try to limit mortality and improve outcome. So far, newer antiepileptic drugs (AED) have not assumed a noticeable role in the treatment of SE. This may be in part due to the lack of IV forms for the newer AEDs. The IV form of Levetiracetam (IV-LEV) has recently become available and has a potential role in the treatment of...... hiện toàn bộ
Metabolic Crisis After Traumatic Brain Injury is Associated with a Novel Microdialysis ProteomeNeurocritical Care - Tập 12 - Trang 324-336 - 2010
R. Lakshmanan, J. A. Loo, T. Drake, J. Leblanc, A. J. Ytterberg, D. L. McArthur, M. Etchepare, P. M. Vespa
To examine if the metabolic distress after traumatic brain injury (TBI) is associated with a unique proteome. Patients with severe TBI prospectively underwent cerebral microdialysis for the initial 96 h after injury. Hourly sampling of metabolism was performed and patients were categorized as having normal or abnormal metabolism as evidenced by the lactate/pyruvate ratio (LPR) threshold of 40. The...... hiện toàn bộ
Impact of Sleep Deprivation in the Neurological Intensive Care Unit: A Narrative ReviewNeurocritical Care - Tập 32 - Trang 596-608 - 2019
Victoria A. Chang, Robert L. Owens, Jamie N. LaBuzetta
Sleep is fundamental for everyday functioning, yet it is often negatively impacted in critically ill patients by the intensive care setting. With a focus on the neurological intensive care unit (NeuroICU), this narrative review summarizes methods of measuring sleep and addresses common causes of sleep disturbance in the hospital including environmental, pharmacological, and patient-related factors...... hiện toàn bộ
NMDA Antagonists for Refractory SeizuresNeurocritical Care - Tập 20 Số 3 - Trang 502-513 - 2014
Zeiler, F. A., Teitelbaum, J., Gillman, L. M., West, M.
Refractory status epilepticus (RSE) poses significant challenge, with a variety of novel therapeutics employed. Our goal was to evaluate the effectiveness of N-methyl d-aspartate (NMDA) receptor antagonists in the control of RSE. We performed a systematic review of all the literature, with all articles pulled from MEDLINE, BIOSIS, EMBASE, Global Health, HealthStar, Scopus, Cochrane Library, the In...... hiện toàn bộ