NeuroImmunoModulation
SCIE-ISI SCOPUS (1994-2002,2004-2025)
1423-0216
1021-7401
Thụy Sĩ
Cơ quản chủ quản: KARGER , S. Karger AG
Lĩnh vực:
Endocrine and Autonomic SystemsImmunologyNeurologyEndocrinology
Các bài báo tiêu biểu
Cytokine Dysregulation, Inflammation and Well-Being
Tập 12 Số 5 - Trang 255-269 - 2005
Cytokines mediate and control immune and inflammatory responses. Complex
interactions exist between cytokines, inflammation and the adaptive responses in
maintaining homeostasis, health, and well-being. Like the stress
response, the inflammatory reaction is crucial for survival and is meant to be
tailored to the stimulus and time. A full-fledged systemic inflammatory reaction
results in sti...
Chronic Pain and Fatigue Syndromes: Overlapping Clinical and Neuroendocrine Features and Potential Pathogenic Mechanisms
Tập 4 Số 3 - Trang 134-153 - 1997
One Hormone, Two Actions: Anti- and Pro-Inflammatory Effects of Glucocorticoids
Tập 22 Số 1-2 - Trang 20-32 - 2015
Glucocorticoids are essential steroid hormones secreted from the adrenal gland
in response to stress. Since their discovery in the 1940s, glucocorticoids have
been widely prescribed to treat inflammatory disorders and hematological
cancers. In the traditional view, glucocorticoids are regarded as
anti-inflammatory molecules; however, emerging evidence suggests that
glucocorticoid actions are more ...
Regulation of the Hypothalamic-Pituitary-Adrenal Axis
Tập 16 Số 5 - Trang 265-271 - 2009
Glucocorticoids (GCs) are essential for the maintenance of homeostasis and
enable the organism to prepare for, respond to and manage stress, either
physical or emotional. Cortisol, the principal GC in humans, is synthesized in
the adrenal cortex. It is released in the circulation in a pulsatile and
circadian pattern. GC secretion is governed by hypothalamus and pituitary. The
hypothalamus senses c...
The Role of Cytokines in the Neuropathology of Stroke and Neurotrauma
Tập 5 Số 3-4 - Trang 143-159 - 1998
Accumulating evidence during the last decade has shown that the CNS can mount a
well-defined inflammatory reaction to a variety of insults including trauma,
ischemia, transplantation, viral infections as well as neurodegeneration. Many
aspects of this centrally derived inflammatory response parallel to some extent
the nature of such a reaction in the periphery. Through the recent application
of mo...
An Age-Related Decline in Interleukin-10 May Contribute to the Increased Expression of Interleukin-6 in Brain of Aged Mice
Tập 9 Số 4 - Trang 183-192 - 2001
Objectives: The DNA-binding activity of nuclear factor ĸB (NFĸB) is
elevated in brain of aged mice, resulting in elevated levels of the inflammatory
cytokine interleukin (IL)-6. The purpose of this study was to determine if in
the brain of aged mice a decrease in the anti-inflammatory cytokine IL-10
contributes to the increase in IL-6. Methods: In initial studies coronal
brain sectio...
Immunosenescence and Immunogenetics of Human Longevity
Tập 15 Số 4-6 - Trang 224-240 - 2008
At present, individuals can live up to 80–120 years, a time much longer than
that of our ancestors, as a consequence of the improvements in life conditions
and medical care. Thus, the human immune system has to cope with a lifelong and
evolutionarily unpredicted exposure to a variety of antigens, which are at the
basis of profound age-related changes globally indicated as immunosenescence, a
multi...
Receptor Biology of the Melanocortins, a Family of Neuroimmunomodulatory Peptides
Tập 3 Số 5 - Trang 259-284 - 1996
Permeability of the Blood-Brain Barrier to Soluble Cytokine Receptors
Tập 2 Số 3 - Trang 161-165 - 1995