Oxidative DNA Damage and Tubulointerstitial Injury in Diabetic NephropathyNephron - Tập 91 Số 2 - Trang 327-329 - 2002
Masao Kanauchi, Hisayuki Nishioka, Toshio Hashimoto
Background: Oxidative stress is an important pathogenetic factor in
underlying diabetic complications. Recently, 8-hydroxy-2′-deoxyguanosine
(8-OHdG) has been reported to serve as a new sensitive biomarker of the
oxidative DNA damage in vivo. We studied the relationship between oxidative DNA
damage and tubulointerstitial injury in patients with diabetic nephropathy.
Methods: Type 2 d... hiện toàn bộ