Nature Chemical Biology
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Snapshots and ensembles of BTK and cIAP1 protein degrader ternary complexes
Nature Chemical Biology - Tập 17 Số 2 - Trang 152-160 - 2021
Convergent evolution of bacterial ceramide synthesis
Nature Chemical Biology - Tập 18 - Trang 305-312 - 2021
The bacterial domain produces numerous types of sphingolipids with various physiological functions. In the human microbiome, commensal and pathogenic bacteria use these lipids to modulate the host inflammatory system. Despite their growing importance, their biosynthetic pathway remains undefined since several key eukaryotic ceramide synthesis enzymes have no bacterial homolog. Here we used genomic...... hiện toàn bộ
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway
Nature Chemical Biology - Tập 4 Số 5 - Trang 295-305 - 2008
Rational design of proteins that exchange on functional timescales
Nature Chemical Biology - Tập 13 Số 12 - Trang 1280-1285 - 2017
Computational design of G Protein-Coupled Receptor allosteric signal transductions
Nature Chemical Biology - Tập 16 Số 1 - Trang 77-86 - 2020
Bottom-up de novo design of functional proteins with complex structural features
Nature Chemical Biology - Tập 17 Số 4 - Trang 492-500 - 2021
A topological and conformational stability alphabet for multipass membrane proteins
Nature Chemical Biology - Tập 12 Số 3 - Trang 167-173 - 2016
Protein lysine methyltransferase G9a acts on non-histone targets
Nature Chemical Biology - Tập 4 Số 6 - Trang 344-346 - 2008
Capture and release of alkyne-derivatized glycerophospholipids using cobalt chemistry
Nature Chemical Biology - Tập 6 Số 3 - Trang 205-207 - 2010
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