Mutagenesis

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* Dữ liệu chỉ mang tính chất tham khảo

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Molecular analyses of <i>Salmonella hisG428</i> ochre revertants for rapid characterization of mutational specificity
Mutagenesis - Tập 11 Số 4 - Trang 341-348 - 1996
Walter Koch, Erik N. Henrikson, Thomas A. Cebula
Modulation of gene expression and DNA-adduct formation in precision-cut liver slices exposed to polycyclic aromatic hydrocarbons of different carcinogenic potency
Mutagenesis - Tập 22 Số 1 - Trang 55-62 - 2007
Yvonne C.M. Staal, Marcel H.M. van Herwijnen, Daphnee S. Pushparajah, Meera Umachandran, Costas Ioannides, Frederik‐Jan van Schooten, Joost H.M. van Delft
Mutations induced by benzo[a]pyrene and dibenzo[a,l]pyrene in lacI transgenic B6C3F1 mouse lung result from stable DNA adducts
Mutagenesis - Tập 23 Số 6 - Trang 445-450
Stephanie A. Leavitt, Michael H. George, Tanya Moore, Jeffrey A. Ross
Genotoxicity biomarkers associated with exposure to traffic and near-road atmospheres: a review
Mutagenesis - Tập 28 Số 5 - Trang 485-505 - 2013
David M. DeMarini
The role of human umbilical cord mesenchymal stem cells-derived exosomal microRNA-431-5p in survival and prognosis of colorectal cancer patients
Mutagenesis - Tập 37 Số 2 - Trang 164-171 - 2022
Muwen Qu, Junyi Li, Hong Zi-fu, Fei Jia, Jun Li, Lingling Yuan
Abstract We aim to discuss the role of miR-431-5p in colorectal cancer (CRC) progression via regulating peroxiredoxin 1 (PRDX1). miR-431-5p and PRDX1 expression were detected in CRC tissues and cells, and the relationship between miR-431-5p expression and prognosis of CRC patients was analyzed. Exosomes were extracted from human umbilical cord mesenchymal stem cells (hUCMSCs) and co-cultured with LoVo cells. MTT assay, flow cytometry and Transwell assay were implemented to test cell viability, apoptosis and invasion and migration ability, respectively. The tumor growth was determined as well, and the binding relation between miR-431-5p and PRDX1 was confirmed. miR-431-5p was downregulated and PRDX1 was upregulated in CRC, and miR-431-5p downregulation was associated with poor prognosis. hUCMSC-Exos suppressed the malignant behaviors of LoVo cells, and overexpression of miR-431-5p further aggravated the inhibitory effect of hUCMSC-Exos on LoVo cells. hUCMSC-Exos inhibited PRDX1 expression via miR-431-5p. PRDX1 was targeted by miR-431-5p. miR-431-5p serves as a prognostic biomarker in CRC, and hUCMSC-Exos transfer of miR-431-5p decelerates CRC cell growth by inhibiting PRDX1.
Evaluation of the mutagenicity of the anti-inflammatory drug salicylazosulfapyridine (SASP)
Mutagenesis - Tập 5 Số 6 - Trang 549-554 - 1990
Jack A. Taylor, Karsten Witt, Dushyant Gulati, James T. MacGregor
Study of the genotoxic potential of 17 mycotoxins with the SOS Chromotest
Mutagenesis - Tập 2 Số 6 - Trang 433-439 - 1987
Serge Krivobok, Patrick Olivier, Daniel Marzin, F. Seigle‐Murandi, R. Steiman
The nature of high frequency sister chromatid exchange cells (HFCs)
Mutagenesis - Tập 12 Số 5 - Trang 329-333 - 1997
Isabella Ponzanelli, Stefano Landi, Francesca Bernacchi, Roberto Barale
Tổng số: 44   
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