Modulation of gene expression and DNA-adduct formation in precision-cut liver slices exposed to polycyclic aromatic hydrocarbons of different carcinogenic potency
Tóm tắt
Từ khóa
Tài liệu tham khảo
IARC, 1973, Certain polycyclic aromatic hydrocarbons and heterocyclic compounds, IARC Monogr. Eval. Carcinog. Risk Chem. Hum., 3, 1
IARC, 1983, Polynuclear aromatic compounds, Part 1, Chemical, environmental and experimental data, IARC Monogr. Eval. Carcinog. Risk Chem. Hum., 32, 1
Melendez-Colon, 2000, Formation of stable DNA adducts and apurinic sites upon metabolic activation of bay and fjord region polycyclic aromatic hydrocarbons in human cell cultures, Chem. Res. Toxicol., 13, 10, 10.1021/tx9802724
Xue, 2005, Metabolic activation of polycyclic and heterocyclic aromatic hydrocarbons and DNA damage: a review, Toxicol. Appl. Pharmacol., 206, 73, 10.1016/j.taap.2004.11.006
Ross, 1995, Adenomas induced by polycyclic aromatic hydrocarbons in strain A/J mouse lung correlate with time-integrated DNA adduct levels, Cancer Res., 55, 1039
Kriek, 1998, Polycyclic aromatic hydrocarbon-DNA adducts in humans: relevance as biomarkers for exposure and cancer risk, Mutat Res., 400, 215, 10.1016/S0027-5107(98)00065-7
Harrigan, 2004, DNA adduct formation in precision-cut rat liver and lung slices exposed to benzo(a)pyrene, Toxicol Sci., 77, 307, 10.1093/toxsci/kfh030
Arif, 1999, DNA adduct formation and persistence in rat tissues following exposure to the mammary carcinogen dibenzo[a,l]pyrene, Carcinogenesis, 20, 1147, 10.1093/carcin/20.6.1147
Segerback, 1993, Recoveries of DNA adducts of polycyclic aromatic hydrocarbons in the 32P-postlabelling assay, Carcinogenesis, 14, 2463, 10.1093/carcin/14.12.2463
Shimada, 2004, Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and 1B1, Cancer Sci., 95, 1, 10.1111/j.1349-7006.2004.tb03162.x
Shimada, 2003, Tissue-specific induction of cytochromes P450 1A1 and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in engineered C57BL/6J mice of arylhydrocarbon receptor gene, Toxicol. Appl. Pharmacol., 187, 1, 10.1016/S0041-008X(02)00035-2
Melendez-Colon, 1999, Cancer initiation by polycyclic aromatic hydrocarbons results from formation of stable DNA adducts rather than apurinic sites, Carcinogenesis, 20, 1885, 10.1093/carcin/20.10.1885
Machala, 2001, Aryl hydrocarbon receptor-mediated activity of mutagenic polycyclic aromatic hydrocarbons determined using in vitro reporter gene assay, Mutat Res., 497, 49, 10.1016/S1383-5718(01)00240-6
Solhaug, 2004, Polycyclic aromatic hydrocarbons induce both apoptotic and anti-apoptotic signals in Hepa1c1c7 cells, Carcinogenesis, 25, 809, 10.1093/carcin/bgh069
Bostrom, 2002, Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient air, Environ. Health Perspect., 110, 451, 10.1289/ehp.02110s3451
Nisbet, 1992, Toxic equivalency factors (TEFs) for polycyclic aromatic hydrocarbons (PAHs), Regul. Toxicol. Pharmacol., 16, 290, 10.1016/0273-2300(92)90009-X
Collins, 1998, Potency equivalency factors for some polycyclic aromatic hydrocarbons and polycyclic aromatic hydrocarbon derivatives, Regul. Toxicol. Pharmacol., 28, 45, 10.1006/rtph.1998.1235
Hu, 2004, Identification of a gene expression profile that discriminates indirect-acting genotoxins from direct-acting genotoxins, Mutat. Res., 549, 5, 10.1016/j.mrfmmm.2003.11.012
van Delft, 2004, Discrimination of genotoxic from non-genotoxic carcinogens by gene expression profiling, Carcinogenesis, 25, 1265, 10.1093/carcin/bgh108
Parrish, 1998, Benzo(a)pyrene-induced alterations in growth-related gene expression and signaling in precision-cut adult rat liver and kidney slices, Toxicol. Appl. Pharmacol., 152, 302, 10.1006/taap.1998.8525
Hashemi, 1999, Structural and functional integrity of precision-cut liver slices in xenobiotic metabolism: a comparison of the dynamic organ and multiwell plate culture procedures, Xenobiotica, 29, 11, 10.1080/004982599238786
Staal, 2005, Application of four dyes in gene expression analyses by microarrays, BMC Genomics, 6, 101, 10.1186/1471-2164-6-101
Tibshirani, 2002, Diagnosis of multiple cancer types by shrunken centroids of gene expression, Proc. Natl Acad. Sci. USA, 99, 6567, 10.1073/pnas.082099299
Doniger, 2003, MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data, Genome Biol., 4, R7, 10.1186/gb-2003-4-1-r7
Dahlquist, 2002, GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways, Nat. Genet., 31, 19, 10.1038/ng0502-19
Reddy, 1986, Nuclease P1-mediated enhancement of sensitivity of 32P-postlabeling test for structurally diverse DNA adducts, Carcinogenesis, 7, 1543, 10.1093/carcin/7.9.1543
Godschalk, 1998, Differences in aromatic-DNA adduct levels between alveolar macrophages and subpopulations of white blood cells from smokers, Carcinogenesis, 19, 819, 10.1093/carcin/19.5.819
Bardwell, 1998, Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins, Proc. Natl Acad. Sci. USA, 95, 15400, 10.1073/pnas.95.26.15400
Knight, 1999, cDNA cloning, expression and activity of a second human aflatoxin B1-metabolizing member of the aldo-keto reductase superfamily, AKR7A3, Carcinogenesis, 20, 1215, 10.1093/carcin/20.7.1215
Spivack, 2003, Phase I and II carcinogen metabolism gene expression in human lung tissue and tumors, Clin Cancer Res., 9, 6002
Staal, 2006, Modulation of gene expression and DNA adduct formation in HepG2 cells by polycyclic aromatic hydrocarbons with different carcinogenic potencies, Carcinogenesis, 27, 646, 10.1093/carcin/bgi255
Wu, 1998, Critical role of both retinoid nuclear receptors and retinoid-X-receptors in mediating growth inhibition of ovarian cancer cells by all-trans retinoic acid, Oncogene, 17, 2839, 10.1038/sj.onc.1202208
Letterio, 2005, Disruption of the TGF-beta pathway and modeling human cancer in mice, Mutat Res., 576, 120, 10.1016/j.mrfmmm.2005.03.004
Lichtor, 1986, Respiratory patterns in human brain tumors, Neurosurgery, 19, 896, 10.1227/00006123-198612000-00002
Rao, 1995, The significance of the cholesterol biosynthetic pathway in cell growth and (review), Anticancer Res., 15, 309
Bannasch, 1997, Early bioenergetic changes in hepatocarcinogenesis: preneoplastic phenotypes mimic responses to insulin and thyroid hormone, J. Bioenerg. Biomembr., 29, 303, 10.1023/A:1022438528634
Uno, 2006, Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate, Mol. Pharmacol., 69, 1103, 10.1124/mol.105.021501
Fletcher, 2005, 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) alters the mRNA expression of critical genes associated with cholesterol metabolism, bile acid biosynthesis, and bile transport in rat liver: a microarray study, Toxicol. Appl. Pharmacol., 207, 1, 10.1016/j.taap.2004.12.003
Moss, 2005, Mechanisms of disease: Inflammation and the origins of cancer, Nat. Clin. Pract. Oncol., 2, 90, 10.1038/ncponc0081
Li, 2002, Expression of inflammation related enzymes during experimental rat lung carcinogenesis, Zhonghua Zhong Liu Za Zhi, 24, 316
Gao, 2002, Dynamic changes of matrix metalloproteinases in rat liver during the development of diethylnitrosamine-induced hepatocarcinoma, Di Yi Jun Yi Da Xue Xue Bao, 22, 865