Molecular Neurobiology

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Injectable Hydrogel Containing Tauroursodeoxycholic Acid for Anti-neuroinflammatory Therapy After Spinal Cord Injury in Rats
Molecular Neurobiology - - 2020
Gong Ho Han, Seong Jun Kim, Wan‐Kyu Ko, Daye Lee, Jae Seo Lee, Haram Nah, Inbo Han, Seil Sohn
Pinocembrin Suppresses H2O2-Induced Mitochondrial Dysfunction by a Mechanism Dependent on the Nrf2/HO-1 Axis in SH-SY5Y Cells
Molecular Neurobiology - Tập 55 - Trang 989-1003 - 2017
Marcos Roberto de Oliveira, Gustavo da Costa Ferreira, Flávia Bittencourt Brasil, Alessandra Peres
Mitochondria are susceptible to redox impairment, which has been associated with neurodegeneration. These organelles are both a source and target of reactive species. In that context, there is increasing interest in finding natural compounds that modulate mitochondrial function and mitochondria-related signaling in order to prevent or to treat diseases involving mitochondrial impairment. Herein, w...... hiện toàn bộ
Persistent mitoKATP Activation Is Involved in the Isoflurane-induced Cytotoxicity
Molecular Neurobiology - Tập 54 Số 2 - Trang 1101-1110 - 2017
Yang, Yan, Chen, Xiufang, Min, Haiyan, Song, Shiyu, Zhang, Juan, Fan, Shanshan, Yi, Long, Wang, Hongwei, Gu, Xiaoping, Ma, Zhengliang, Gao, Qian
Isoflurane exposure induces apoptosis in cultured cells and in the developing brain, while the underlying mechanism remains largely unclarified. This study was designed to determine whether the disruption of mitoKATP-mediated ATP balance was involved in the cytotoxicity of isoflurane. Human neuroglioma cells U251 and 7-day-old mice were treated with isoflurane. A specific mitoKATP antagonist 5-HD ...... hiện toàn bộ
Pro-necrotic Activity of Cationic Mastoparan Peptides in Human Glioblastoma Multiforme Cells Via Membranolytic Action
Molecular Neurobiology - - 2018
Annielle Mendes Brito da Silva, Laíz Costa Silva-Gonçalves, Fernando A. Oliveira, Manoel Arcísio-Miranda
Truyền dẫn synap và tính biến đổi trong hạch hạnh nhân Dịch bởi AI
Molecular Neurobiology - Tập 13 - Trang 1-22 - 1996
Stephen Maren
Nhiều nghiên cứu trên chuột và con người chỉ ra tầm quan trọng của hạch hạnh nhân trong việc tiếp thu và diễn đạt nỗi sợ đã học. Việc xác định hạch hạnh nhân là một cơ sở thần kinh thiết yếu cho điều kiện hóa nỗi sợ đã cho phép thực hiện các nghiên cứu thần kinh sinh lý về các quá trình synap trong hạch hạnh nhân có thể làm trung gian cho điều kiện hóa nỗi sợ. Một cơ chế tế bào có thể cho điều kiệ...... hiện toàn bộ
#hạch hạnh nhân #điều kiện hóa nỗi sợ #truyền dẫn synap #tính biến đổi #NMDA #AMPA
AT2R Activation Prevents Microglia Pro-inflammatory Activation in a NOX-Dependent Manner: Inhibition of PKC Activation and p47phox Phosphorylation by PP2A
Molecular Neurobiology - Tập 56 - Trang 3005-3023 - 2018
Shahnawaz Ali Bhat, Anika Sood, Rakesh Shukla, Kashif Hanif
Microglia-induced reactive oxygen species (ROS) production and inflammation play an imperative role in neurodegenerative diseases like Alzheimer’s disease (AD) and Parkinson’s disease (PD). It has been established that angiotensin II type-2 receptor (AT2R) activation is neuroprotective in central nervous system diseases like stroke and AD. However, the involvement of AT2R in NADPH oxidase (NOX)-me...... hiện toàn bộ
Arachidonic Acid Induces ARE/Nrf2-Dependent Heme Oxygenase-1 Transcription in Rat Brain Astrocytes
Molecular Neurobiology - - 2018
Chih-Chung Lin, Chien-Chung Yang, Yu‐Wen Chen, Li-Der Hsiao, Chih-Hui Yang
The Fragile X Protein and Genome Function
Molecular Neurobiology - Tập 56 Số 1 - Trang 711-721 - 2019
Thomas C. Dockendorff, Mariano Labrador
Correction to: lncRNA NONRATT021972 siRNA Decreases Diabetic Neuropathic Pain Mediated by the P2X3 Receptor in Dorsal Root Ganglia
Molecular Neurobiology - Tập 56 - Trang 6656-6657 - 2019
Haiying Peng, Lifang Zou, Jinyan Xie, Hong Wu, Bing Wu, Gaochun Zhu, Qiulan Lv, Xi Zhang, Shuangmei Liu, Guilin Li, Hong Xu, Yun Gao, Changshui Xu, Chunping Zhang, Shouyu Wang, Yun Xue, Shangdong Liang
In the original version of this article “lncRNA NONRATT021972 siRNA Decreases Diabetic Neuropathic Pain Mediated by the P2X3 Receptor in Dorsal Root Ganglia”, which we have published in Mol Neurobiol (2017) 54:511–523.
The Diagnostic Value of Whole-Exome Sequencing in a Spectrum of Rare Neurological Disorders Associated with Cerebellar Atrophy
Molecular Neurobiology - - Trang 1-13 - 2023
Engy A. Ashaat, Hoda A. Ahmed, Nesma M. Elaraby, Alaaeldin Fayez, Ammal M. Metwally, Mona K. Mekkawy, Dalia Farouk Hussen, Neveen A. Ashaat, Rasha M. Elhossini, Heba Ahmed ElAwady, Randa H. A. Abdelgawad, Mona El Gammal, Mohamed Ahmed Al Kersh, Dina Amin Saleh
Several neurological disorders, neurodevelopmental disorders, and neurodegenerative disorders have a genetic element with various clinical presentations ranging from mild to severe presentation. Neurological disorders are rare multifactorial disorders characterized by dysfunction and degeneration of synapses, neurons, and glial cells which are essential for movement, coordination, muscle strength,...... hiện toàn bộ
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