Metallomics

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Cobalt chloride speciation, mechanisms of cytotoxicity on human pulmonary cells, and synergistic toxicity with zinc
Metallomics - Tập 5 Số 2 - Trang 133 - 2013
Carole Bresson, Carine Darolles, Asunción Carmona, Céline Gautier, Nicole Sage, Stéphane Roudeau, Richard Ortega, É. Ansoborlo, Véronique Malard
Differential effects of metal ions on TCDD-induced cytotoxicity and cytochrome P4501A1 gene expression in a zebrafish liver (ZFL) cell-line
Metallomics - Tập 8 Số 2 - Trang 236-251
Ying Ying Chen, King Ming Chan

Trace metal ions and trace organic compounds are common co-contaminants in the environment that pose risks to human health.

Huntington’s disease genotype suppresses global manganese-responsive processes in pre-manifest and manifest YAC128 mice
Metallomics - Tập 12 Số 7 - Trang 1118-1130 - 2020
Anna C. Pfalzer, Jordyn M. Wilcox, Simona G. Codreanu, Melissa S. Totten, Terry Jo Bichell, Timothy C. Halbesma, Preethi Umashanker, Kevin Yang, Nancy L. Parmalee, Stacy D. Sherrod, Keith M. Erikson, Fiona E. Harrison, John A. McLean, Michael Aschner, Aaron B. Bowman
Abstract Manganese (Mn) is an essential micronutrient required for the proper function of several enzymes. Accumulating evidence demonstrates a selective decrease of bioavailable Mn in vulnerable cell types of Huntington’s Disease (HD), an inherited progressive neurodegenerative disorder with no cure. Amelioration of underlying pathophysiology, such ...... hiện toàn bộ
Evidence for widespread, severe brain copper deficiency in Alzheimer's dementia
Metallomics - Tập 9 Số 8 - Trang 1106-1119
Jingshu Xu, Stephanie J. Church, Stefano Patassini, Paul Begley, Henry J. Waldvogel, Maurice A. Curtis, Richard L. M. Faull, Richard D. Unwin, Garth J. S. Cooper

Widespread brain-copper deficiency in patients with Alzheimer's dementia (red) compared to controls (blue).

Reactivity–activity relationships of oral anti-diabetic vanadium complexes in gastrointestinal media: an X-ray absorption spectroscopic study
Metallomics - Tập 6 Số 10 - Trang 1880-1888
Aviva Levina, Andrew I. McLeod, Lauren E. Kremer, Jade B. Aitken, C. J. Glover, Bernt Johannessen, Peter A. Lay

X-ray absorption near edge structure (XANES) speciation of vanadium pro-drugs in artificial digestive juices has delineated biotransformations after oral administration.

Biodistribution and long-term fate of silver nanoparticles functionalized with bovine serum albumin in rats
Metallomics - Tập 2 Số 3 - Trang 204-210
Lourdes Garza-Ocañas, D. Ferrer, Justin L. Burt, L.A. Dı́az-Torres, Mónica Ramírez Cabrera, Victor Tamez Rodríguez, Rubén Lujàn Rangel, Dwight K. Romanovicz, Miguel José‐Yacamán
Metallothionein polymorphisms in pathological processes
Metallomics - Tập 6 Số 1 - Trang 55-68
Martina Raudenská, Jaromír Gumulec, Ondřej Podlaha, Markéta Sztalmachová, Petr Babula, Tomáš Eckschlager, Vojtěch Adam, René Kizek, Michal Masařík
The “magic numbers” of metallothionein
Metallomics - Tập 3 Số 5 - Trang 444 - 2011
Duncan E. K. Sutherland, Martin J. Stillman
Metallochaperone-like genes in Arabidopsis thaliana
Metallomics - Tập 2 Số 8 - Trang 556 - 2010
Muhammad Tehseen, Narelle Cairns, Sarah M. Sherson, Christopher S. Cobbett
Trehalose alleviates cadmium-induced brain damage by ameliorating oxidative stress, autophagy inhibition, and apoptosis
Metallomics - Tập 11 Số 12 - Trang 2043-2051
Kou-Kou Tang, Xinyu Liu, Zhen‐Yong Wang, Kui-Chao Qu, Ruifeng Fan

Tre antagonizes Cd-induced brain injury by suppressing oxidative stress and autophagy inhibition, ultimately inhibiting apoptosis. Especially, persistent activation of Nrf2 contributes to tissue damage, rather than playing an active protective role.

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