Trehalose alleviates cadmium-induced brain damage by ameliorating oxidative stress, autophagy inhibition, and apoptosis

Metallomics - Tập 11 Số 12 - Trang 2043-2051
Kou-Kou Tang1,2,3,4,5, Xinyu Liu1,2,3,4,5, Zhen‐Yong Wang1,2,3,4,5, Kui-Chao Qu1,2,3,4,5, Ruifeng Fan1,2,3,4,5
1China
2College of Animal Science and Veterinary Medicine
3Shandong agricultural University
4Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention
5Tai’an City

Tóm tắt

Tre antagonizes Cd-induced brain injury by suppressing oxidative stress and autophagy inhibition, ultimately inhibiting apoptosis. Especially, persistent activation of Nrf2 contributes to tissue damage, rather than playing an active protective role.

Từ khóa


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