Metabolomics
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Serum metabolic fingerprinting of psoriasis and psoriatic arthritis patients using solid-phase microextraction—liquid chromatography—high-resolution mass spectrometry
Metabolomics - Tập 17 - Trang 1-12 - 2021
Psoriatic arthritis (PsA), an inflammatory arthritis that develops in individuals with psoriasis, is associated with reduced quality of life. Identifying biomarkers associated with development of PsA as well as with PsA disease activity may help management of psoriatic disease. To use metabolomic fingerprinting to determine potential candidate markers of disease conversion (psoriasis to PsA) and/o...... hiện toàn bộ
Metabolomics as a tool for the authentication of rose extracts used in flavour and fragrance area
Metabolomics - Tập 12 - Trang 1-11 - 2016
Natural extracts used in flavour and fragrances are exposed to authentication issues. Companies working in this industrial market acquire the raw materials locally but also abroad, sourcing exotic plants with specific olfactive features or lower costs of production. The geographical origin, the botanical variety, environmental conditions, extraction processes and storage conditions represent some ...... hiện toàn bộ
Intakes of whey protein hydrolysate and whole whey proteins are discriminated by LC–MS metabolomics
Metabolomics - Tập 10 - Trang 719-736 - 2013
Whey protein improves fasting lipids and insulin response in overweight and obese individuals. Whey hydrolysate was recently shown to be more active than whole protein but the differences in metabolite profiles after intake remain unknown. This study discriminates plasma profiles after intake of four different whey protein fractions and establishes new hypotheses for the observed effects. Obese, n...... hiện toàn bộ
Comprehensive metabolome analysis for the pharmacological action of inchinkoto, a hepatoprotective herbal medicine
Metabolomics - - 2021
The precise pharmacological action of inchinkoto (ICKT, Yin-Chen-Hao-Tang in Chinese), a hepatoprotective herbal medicine, on total metabolic pathways has not been well investigated. The aim of this study was to explore the serum metabolites reflecting the pharmacological activity of ICKT, and mechanism of action of ICKT using serum metabolome analysis. 54 patients with obstructive jaundice due to...... hiện toàn bộ
Evaluation of the use of untargeted metabolomics in the safety assessment of genetically modified crops
Metabolomics - Tập 16 - Trang 1-15 - 2020
The safety assessment of foods and feeds from genetically modified (GM) crops includes the comparison of key characteristics, such as crop composition, agronomic phenotype and observations from animal feeding studies compared to conventional counterpart varieties that have a history of safe consumption, often including a near isogenic variety. The comparative compositional analysis of GM crops has...... hiện toàn bộ
Functional analysis of isoprenoid precursors biosynthesis by quantitative metabolomics and isotopologue profiling
Metabolomics - Tập 15 Số 9 - 2019
Maternal exposure to polystyrene microplastics alters placental metabolism in mice
Metabolomics - Tập 19 - Trang 1-8 - 2022
The rapid growth in the worldwide use of plastics has resulted in a vast accumulation of microplastics in the air, soil and water. The impact of these microplastics on pregnancy and fetal development remains largely unknown. In pregnant mice, we recently demonstrated that exposure to micro- and nanoplastics throughout gestation resulted in significant fetal growth restriction. One possible explana...... hiện toàn bộ
Optimizing water suppression for quantitative NMR-based metabolomics: a tutorial review
Metabolomics - - 2015
Identification of putative biomarkers for prediabetes by metabolome analysis of rat models of type 2 diabetes
Metabolomics - Tập 11 - Trang 1277-1286 - 2015
Biomarkers for the development of type 2 diabetes (T2D) are useful for prediction and intervention of the disease at earlier stages. In this study, we performed a longitudinal study of changes in metabolites using an animal model of T2D, the spontaneously diabetic Torii (SDT) rat. Fasting plasma samples of SDT and control Sprague-Dawley (SD) rats were collected from 6 to 24 weeks of age, and subje...... hiện toàn bộ
Xác định chất chuyển hóa tự động từ phổ 1H NMR của dịch sinh học Dịch bởi AI
Metabolomics - Tập 13 - Trang 1-7 - 2017
Việc xác định chất chuyển hóa trong các mẫu sinh học bằng phổ cộng hưởng từ hạt nhân (NMR) là một nhiệm vụ khó khăn do độ phức tạp của các ma trận sinh học. Bài báo này giới thiệu một sơ đồ tính toán tự động mới cho việc xác định các chất chuyển hóa trong phổ 1D 1H NMR dựa trên Cơ sở Dữ liệu Chất chuyển hóa Con người. Sơ đồ phương pháp bao gồm các bước áp dụng tuần tự của tiền xử lý, giảm dữ liệu,...... hiện toàn bộ
#chất chuyển hóa #phổ NMR #xác định tự động #phân tích chuyển hóa #cơ sở dữ liệu chất chuyển hóa
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