Upregulation of MicroRNA-210 Regulates Renal Angiogenesis Mediated by Activation of VEGF Signaling Pathway under Ischemia/Perfusion Injury in vivo and in vitro Tập 35 Số 3 - Trang 182-191 - 2012
Yong Li, Yuanlei Lou, Jue Wu, Qiongfang Ruan, An Xie, Fei Guo, Cui Su-ping, Zhifeng Deng, Yang Wang
<i>Background:</i> MicroRNAs (miRNAs) are endogenous, non-coding, small RNAs that regulate gene expression and function, but little is known about regulation of miRNAs in the kidneys under normal or pathologic conditions. Here, we sought to investigate the potential involvement of miRNAs in renal ischemia/reperfusion (I/R) injury and angiogenesis and to define some of the miRNA...... hiện toàn bộ Physical Performance and Clinical Outcomes in Dialysis Patients: A Secondary Analysis of the Excite Trial Tập 39 Số 2-3 - Trang 205-211 - 2014
Claudia Torino, Fabio Manfredini, Davide Bolignano, Filippo Aucella, Rossella Baggetta, Antonio Barillà, Yuri Battaglia, Silvio Bertoli, Graziella Bonanno, Pietro Castellino, Daniele Ciurlino, Adamasco Cupisti, Graziella D’Arrigo, Luciano de Paola, Fabrizio Fabrizi, Pasquale Fatuzzo, Giorgio Fuíano, Luigi Lombardi, Gaetano Lucisano, Piergiorgio Messa, Renato Rapanà, Francesco Rapisarda, Stefania Rastelli, Lisa Rocca-Rey, Chiara Summaria, A Zuccalà, Giovanni Tripepi, Luigi Catizone, Carmine Zoccali, Francesca Mallamaci
<b><i>Background/Aims: </i></b>Scarce physical activity predicts shorter survival in dialysis patients. However, the relationship between physical (motor) fitness and clinical outcomes has never been tested in these patients. <b><i>Methods: </i></b>We tested the predictive power of an established metric of motor fitness, the Six-Minute Walkin...... hiện toàn bộ Barriers to Physical Activity in Chronic Hemodialysis Patients: A Single-Center Pilot Study in an Italian Dialysis Facility Tập 39 Số 2-3 - Trang 169-175 - 2014
Enrico Fiaccadori, Alice Sabatino, Franco Schito, Francesca Angella, Martina Malagoli, Marco Tucci, Adamasco Cupisti, Alessandro Capitanini, Giuseppe Regolisti
<b><i>Background/Aims: </i></b>In patients on chronic dialysis a sedentary lifestyle is a strong, yet potentially modifiable, predictor of mortality. The present single-center pilot study evaluated social, psychological and clinical barriers that may hinder physical activity in this population. <b><i>Methods: </i></b>We explored the associati...... hiện toàn bộ Dialysis Exercise Team: The Way to Sustain Exercise Programs in Hemodialysis Patients Tập 39 Số 2-3 - Trang 129-133 - 2014
Alessandro Capitanini, Sara Lange, Claudia D’Alessandro, Emilio Salotti, Alba Tavolaro, Maria Enrica Baronti, Domenico Giannese, Adamasco Cupisti
Patients affected by end-stage renal disease (ESRD) show quite lower physical activity and exercise capacity when compared to healthy individuals. In addition, a sedentary lifestyle is favoured by lack of a specific counseling on exercise implementation in the nephrology care setting. Increasing physical activity level should represent a goal for every dialysis patient care management. Thr...... hiện toàn bộ Osteoporosis and Impaired Trabecular Bone Score in Hemodialysis Patients Tập 41 Số 3 - Trang 345-354 - 2016
Ludmila Brunerová, Petra Ronová, Jana Verešová, Petra Beranová, Jana Potoèková, Petr Kasalický, Ivan Rychlík
<b><i>Background/Aims: </i></b>Small attention is paid to other types of bone diseases then chronic kidney disease-mineral and bone disorder in dialysis patients. The aim of our study was to assess the occurrence of osteoporosis and bone microarchitecture by trabecular bone score in this population. <b><i>Methods: </i></b>59 patients (67.6 ± ...... hiện toàn bộ Inhibition of Phosphate-Induced Vascular Smooth Muscle Cell Osteo-/Chondrogenic Signaling and Calcification by Bafilomycin A1 and Methylamine Tập 40 Số 5 - Trang 490-499 - 2015
Ioana Alesutan, Katharina Musculus, Tatsiana Castor, Kousi Alzoubi, Jakob Voelkl, Florian Läng
<b><i>Background/Aims: </i></b>Excessive phosphate concentrations trigger vascular calcification, an active process promoted by osteoinduction of vascular smooth muscle cells (VSMCs) with increased expression and activity of transcription factor RUNX2 (Core-binding factor α1, CBFA1), alkaline phosphatase (ALPL), TGFß1, transcription factor NFAT5, and NFAT5-sensitive...... hiện toàn bộ