Upregulation of MicroRNA-210 Regulates Renal Angiogenesis Mediated by Activation of VEGF Signaling Pathway under Ischemia/Perfusion Injury in vivo and in vitro Tập 35 Số 3 - Trang 182-191 - 2012
Yong Li, Yuanlei Lou, Jue Wu, Qiongfang Ruan, An Xie, Fei Guo, Cui Su-ping, Zhifeng Deng, Yang Wang
Background: MicroRNAs (miRNAs) are endogenous, non-coding, small RNAs
that regulate gene expression and function, but little is known about regulation
of miRNAs in the kidneys under normal or pathologic conditions. Here, we sought
to investigate the potential involvement of miRNAs in renal ischemia/reperfusion
(I/R) injury and angiogenesis and to define some of the miRNAs possibly
associate... hiện toàn bộ
Physical Performance and Clinical Outcomes in Dialysis Patients: A Secondary Analysis of the Excite Trial Tập 39 Số 2-3 - Trang 205-211 - 2014
Claudia Torino, Fabio Manfredini, Davide Bolignano, Filippo Aucella, Rossella Baggetta, Antonio Barillà, Yuri Battaglia, Silvio Bertoli, Graziella Bonanno, Pietro Castellino, Daniele Ciurlino, Adamasco Cupisti, Graziella D’Arrigo, Luciano de Paola, Fabrizio Fabrizi, Pasquale Fatuzzo, Giorgio Fuíano, Luigi Lombardi, Gaetano Lucisano, Piergiorgio Messa, Renato Rapanà, Francesco Rapisarda, Stefania Rastelli, Lisa Rocca-Rey, Chiara Summaria, A Zuccalà, Giovanni Tripepi, Luigi Catizone, Carmine Zoccali, Francesca Mallamaci
Background/Aims: Scarce physical activity predicts shorter
survival in dialysis patients. However, the relationship between physical
(motor) fitness and clinical outcomes has never been tested in these patients.
Methods: We tested the predictive power of an established metric
of motor fitness, the Six-Minute Walking Test (6MWT), for death, cardiovascular
events and hosp... hiện toàn bộ
Barriers to Physical Activity in Chronic Hemodialysis Patients: A Single-Center Pilot Study in an Italian Dialysis Facility Tập 39 Số 2-3 - Trang 169-175 - 2014
Enrico Fiaccadori, Alice Sabatino, Franco Schito, Francesca Angella, Martina Malagoli, Marco Tucci, Adamasco Cupisti, Alessandro Capitanini, Giuseppe Regolisti
Background/Aims: In patients on chronic dialysis a sedentary
lifestyle is a strong, yet potentially modifiable, predictor of mortality. The
present single-center pilot study evaluated social, psychological and clinical
barriers that may hinder physical activity in this population. Methods:
We explored the association between barriers to physical activity and
sedentarism... hiện toàn bộ
Dialysis Exercise Team: The Way to Sustain Exercise Programs in Hemodialysis Patients Tập 39 Số 2-3 - Trang 129-133 - 2014
Alessandro Capitanini, Sara Lange, Claudia D’Alessandro, Emilio Salotti, Alba Tavolaro, Maria Enrica Baronti, Domenico Giannese, Adamasco Cupisti
Patients affected by end-stage renal disease (ESRD) show quite lower physical
activity and exercise capacity when compared to healthy individuals. In
addition, a sedentary lifestyle is favoured by lack of a specific counseling on
exercise implementation in the nephrology care setting. Increasing physical
activity level should represent a goal for every dialysis patient care
management. Three cruci... hiện toàn bộ
Osteoporosis and Impaired Trabecular Bone Score in Hemodialysis Patients Tập 41 Số 3 - Trang 345-354 - 2016
Ludmila Brunerová, Petra Ronová, Jana Verešová, Petra Beranová, Jana Potoèková, Petr Kasalický, Ivan Rychlík
Background/Aims: Small attention is paid to other types of bone
diseases then chronic kidney disease-mineral and bone disorder in dialysis
patients. The aim of our study was to assess the occurrence of osteoporosis and
bone microarchitecture by trabecular bone score in this population.
Methods: 59 patients (67.6 ± 13.1 years, 43 males) treated with
hemodiafIltration und... hiện toàn bộ
Inhibition of Phosphate-Induced Vascular Smooth Muscle Cell Osteo-/Chondrogenic Signaling and Calcification by Bafilomycin A1 and Methylamine Tập 40 Số 5 - Trang 490-499 - 2015
Ioana Alesutan, Katharina Musculus, Tatsiana Castor, Kousi Alzoubi, Jakob Voelkl, Florian Läng
Background/Aims: Excessive phosphate concentrations trigger
vascular calcification, an active process promoted by osteoinduction of vascular
smooth muscle cells (VSMCs) with increased expression and activity of
transcription factor RUNX2 (Core-binding factor α1, CBFA1), alkaline phosphatase
(ALPL), TGFß1, transcription factor NFAT5, and NFAT5-sensitive transcription
factor SOX9. The ... hiện toàn bộ
Heavy Alcohol Consumption Effects on Blood Pressure and on Kidney Structure Persist After Long-Term Withdrawal Tập 42 Số 4 - Trang 664-675 - 2017
Sandra Leal, Dinis-Oliveira Ricardo Jorge, Joana Barbosa, Susana Maria Silva, Sacco Isabel
Background/Aims: Heavy ethanol consumption is a risk factor for
hypertension and prompts organ damage. There is no information regarding the
impact of long-term heavy ethanol consumption on kidney structure and function
linking to their hypertensive effects nor the repercussions after withdrawal.
Methods: Rats were exposed to ethanol for 24 weeks and,
afterwards, a grou... hiện toàn bộ
The Nrf2/HO-1 Pathway Mediates the Antagonist Effect of L-Arginine On Renal Ischemia/Reperfusion Injury in Rats Tập 42 Số 3 - Trang 519-529 - 2017
Fei Tong, Xinmei Zhou
Background/Aims: Ischemia/reperfusion (I/R) is the most common
cause of acute renal injury. I/R-induced oxidative stress is involved in the
development of acute renal injury, which can be reversed by supplementation with
L-arginine, a precursor of nitric oxide (NO). This study was conducted to
evaluate alterations in the expression of transcription factors [nuclear factor
kappa B (NF... hiện toàn bộ