Journal of the Egyptian National Cancer Institute
SCOPUS (2005-2009,2011-2025)ESCI-ISI
2589-0409
Cơ quản chủ quản: National Cancer Institute , SPRINGER
Lĩnh vực:
OncologyCancer Research
Phân tích ảnh hưởng
Các bài báo tiêu biểu
Anti-angiogenesis in cancer therapeutics: the magic bullet
- 2021
Abstract Background Angiogenesis is the formation of new vascular networks from
preexisting ones through the migration and proliferation of differentiated
endothelial cells. Available evidence suggests that while antiangiogenic therapy
could inhibit tumour growth, the response to these agents is not sustained. The
aim of this paper was to review the evidence for anti-angiogenic therapy in
cancer t...
Podophyllotoxin-polyacrylic acid conjugate micelles: improved anticancer efficacy against multidrug-resistant breast cancer
Tập 32 Số 1 - 2020
Abstract Background Podophyllotoxin (PPT) is a naturally occurring compound
obtained from the roots of Podophyllum species, indicated for a variety of
malignant tumors such as breast, lung, and liver tumors. This toxic polyphenol
(PPT) exhibited significant activity against P-glycoprotein (P-gp) mediated
multidrug-resistant (MDR) cancer cells. However, extremely poor water
solubility, a narrow the...
Thyroid cancer associated with Hashimoto thyroiditis: similarities and differences in an endemic area
Tập 32 Số 1 - 2020
Abstract Background Hashimoto thyroiditis (HT) is an autoimmune lymphocytic
thyroiditis and is the most common form of thyroid inflammatory diseases. The
association of HT with papillary thyroid carcinoma (PTC) has been described. PTC
is the most common form of malignancy associated with HT. When papillary
carcinoma develops on top of Hashimoto thyroiditis, the disease tends to be less
aggressive ...
Oral carcinoma cuniculatum: an unacquainted entity with diagnostic challenges—a case report
Tập 34 Số 1 - 2022
Abstract Background Oral carcinoma cuniculatum (OCC) is an unacquainted
well-differentiated subtype of oral squamous cell carcinoma, which displays
unique clinic-pathological features. Up to date, OCC remains rare with about 75
reported cases, and is frequently missed or even misdiagnosed. Case presentation
The aim of the present work was: to report a case of OCC in mandibular gingiva
and to highl...
Feasibility of Monte-Carlo algorithm in comparison with collapse-cone dose calculation algorithm of a commercial treatment planning system in the presence of high-density metallic implant: a dosimetric study
- 2021
Abstract Background The number of people with implanted hip prosthesis has grown
worldwide. For radiotherapy planning of patients with hip implants, few main
challenges are encountered. The aim of the present study was to evaluate the
feasibility of different planning algorithms in the presence of high-density
metallic implant in the treatment of patients with carcinoma cervix. Results It
was foun...
Studying ferroptosis and iron metabolism pre- and post-radiotherapy treatment in breast cancer patients
Abstract Background Radiotherapy (RT) is an important part of the treatment of
many tumors. Radiotherapy causes oxidative damage in all cellular compartments,
including lipid membrane, on a random basis. Toxic lipid peroxidation
accumulation has only lately been linked to a regulated type of cell death known
as ferroptosis. Iron is required for ferroptosis sensitization in cells. Aim of
the work T...
Axillary nodal metastasis in ovarian cancer: a report of three cases and review of literature
- 2019
Abstract Background Ovarian cancer represents a major global health burden that
is rarely associated with distant metastasis. Axillary lymph node metastasis
from ovarian cancer is rare and is reported only in few case reports in
literature. Case presentation We report three cases of ovarian carcinoma
associated with axillary lymph node metastasis as well as a brief literature
review. The pathologi...
Demographics, clinical features, and prognosis of rare lymphoepithelioma-like carcinoma across different anatomic sites
Tập 34 Số 1 - 2022
Abstract Background Lymphoepithelioma-like carcinoma (LELC) is an unusual
histological malignancy type. Due to the rarity of this disease, we used the
Surveillance, Epidemiology, and End Results (SEER) database to investigate
comprehensively and systematically the prognosis factor of LELC. Methods We
identified 2079 patients diagnosed with LELC during 1973–2015 from the SEER
database. LELC was cla...
Spectrum of EGFR mutation and its relation with high-risk predictors in thyroid cancer in Kashmiri population: 2 years prospective study at a tertiary care hospital
Abstract Background EGFR mutation has not been extensively studied in thyroid
cancer. This study was conducted to study spectrum of EGFR mutation in thyroid
cancer in Kashmiri population for possible therapeutic purpose. Methods It was 2
years prospective cross-sectional study conducted at a tertiary care center in
which histologically confirmed, untreated thyroid cancers were included. These
spec...
Correlation of miR-31 and miR-373 expression with KRAS mutations and its impact on prognosis in colorectal cancer
Tập 34 Số 1
Abstract Introduction Colorectal cancers (CRC) are among the most common
cancers. There are different modalities for treatment including chemotherapy,
surgery, and radiotherapy. There are some mutations in cancers which can assist
in the treatment and better prognosis of patients. In this study, two molecular
markers (miR-31 and miR-373) were involved in the pathogenesis of CRC and their
associati...