The Calcium-Dependent Protease Calpain-1 Links TRPC6 Activity to Podocyte InjuryJournal of the American Society of Nephrology : JASN - Tập 29 Số 8 - Trang 2099-2109 - 2018
Kim A.T. Verheijden, Ramon Sonneveld, Marinka Bakker-van Bebber, Jack F.M. Wetzels, Johan van der Vlag, Tom Nijenhuis
Background
The hallmark of podocytopathies, such as FSGS, is podocyte injury resulting in proteinuria. Transient receptor potential channel C6 (TRPC6) is a calcium-conducting ion channel expressed at the slit diaphragm. TRPC6 gain-of-function mutations and glomerular TRPC6 overexpression are associated with proteinuria. However, t...... hiện toàn bộ
Hypertension Is a Major Contributor to 20-Hydroxyeicosatetraenoic Acid–Mediated Kidney Injury in Diabetic NephropathyJournal of the American Society of Nephrology : JASN - Tập 26 Số 3 - Trang 597-610 - 2015
Mahesha Gangadhariah, James M. Luther, Víctor García, Paisit Paueksakon, Ming Zhi Zhang, Simon W. Hayward, Harold D. Love, John R. Falck, Vijaya L. Manthati, John D. Imig, Michal L. Schwartzman, Roy Zent, Jorge H. Capdevila, Ambra Pozzi
New Approaches to the Treatment of Dense Deposit DiseaseJournal of the American Society of Nephrology : JASN - Tập 18 Số 9 - Trang 2447-2456 - 2007
Richard J. Smith, Jessy J. Alexander, Paul N. Barlow, Marina Botto, Thomas L. Cassavant, H. Terence Cook, Santiago Rodrı́guez de Córdoba, Gregory S. Hageman, T. Sakari Jokiranta, William J. Kimberling, John D. Lambris, Lynne D. Lanning, Vicki Levidiotis, Christoph Licht, Hans Lutz, Seppo Meri, Matthew C. Pickering, Richard J. Quigg, Angelique L. Rops, David J. Salant, Sanjeev Sethi, Joshua M. Thurman, Hope F. Tully, Sean P. Tully, Johan van der Vlag, Patrick D. Walker, Reinhard WuCombining Diaeresisrzner, Peter F. Zipfel