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Journal of bioenergetics

SCOPUS (1976-2023)SCIE-ISI

  1573-6881

  0449-5705

 

 

Cơ quản chủ quản:  SPRINGER/PLENUM PUBLISHERS , Springer New York

Lĩnh vực:
Cell BiologyPhysiology

Phân tích ảnh hưởng

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We have examined the substrate specificity and inhibitor sensitivity of H2O2 formation by rat heart mitochondria. Active H2O2 production requires both a high fractional reduction of Complex I (indexed by NADH/NAD+ + NADH ratio) and a high membrane potential, ΔΨ. These conditions are achieved with supraphysiological concentrations of succinate. With physiological concentrations of NAD-linked substr...... hiện toàn bộ
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