Journal of Tongji Medical University
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Mechanism of dynamic near-infrared fluorescence cholangiography of extrahepatic bile ducts and applications in detecting bile duct injuries using indocyanine green in animal models
Journal of Tongji Medical University - Tập 37 - Trang 44-50 - 2017
Fluorescence intraoperative cholangiography (IOC) is a potential alternative for identifying anatomical variation and preventing iatrogenic bile duct injuries by using the near-infrared probe indocyanine green (ICG). However, the dynamic process and mechanism of fluorescence IOC have not been elucidated in previous publications. Herein, the optical properties of the complex of ICG and bile, dynami......
Special form of collagen fibrils
Journal of Tongji Medical University - Tập 4 - Trang 187-190 - 1984
We found a special form of collagen fibrils in tentorium cerebelli and internal cranial periost of hen with two characteristics under electron-microscope:
The possibility and significance of such special collagen fibril......
Antisense oligodeoxynucleotide inhibits expression of recombinant porcine follicle-stimulating hormone receptor
Journal of Tongji Medical University - Tập 19 - Trang 175-180 - 1999
To assess the role of follicle-stimulating hormone receptor (FSHR) gene expression in regulating expression of FSHR protein in the plasma membrane, the effects of a porcine FSHR cDNA antisense oligodeoxynucleotide (ODN) on FSHR mRNA levels and 125I-FSH binding were determined in Chinese hamster ovary cells expression recombinant porcine FSHR (pFSHR-CHO cells). An 18-mer phosphorothioate-endcapped ......
Immunohistological study on the mechanism of mesangial proliferation
Journal of Tongji Medical University - Tập 16 - Trang 173-178 - 1996
Inflammatory cells infiltrated in glomeruli and proliferating glomerular cells were immunohistochemically studied in 87 renal biopsies from patients with glomerulonephritides (GN) of various types, by using monoclonal antibody to Mac387 and PCNA (proliferative cell nuclear antigen) respectively. The results showed that the expressions of Mac387 and PCNA were generally increased in proliferative GN......
Methodological studies on plasma endotoxin level and endotoxin inactivation capacity
Journal of Tongji Medical University - Tập 24 - Trang 581-584 - 2004
To establish stable methods for detecting plasma endotoxin level and endotoxin inactivation capacity in a normal population and general surgical patients and evaluate their perioperative changes, 50 healthy people and 50 patients receiving gastrointestinal operation were enrolled, their plasma endotoxin levels and plasma endotoxin inactivation capacity were assayed. Our results showed that plasma ......
Effect of NADPH oxidase inhibitor apocynin on the expression of hypoxia-induced factor-1α and endothelin-1 in rat carotid body exposed to chronic intermittent hypoxia
Journal of Tongji Medical University - - 2013
The effects of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase inhibitor apocynin on the enhanced hypoxia induced factor-1α (HIF-1α) and endothelin-1 (ET-1) expression, elevated systolic blood pressure under chronic intermittent hypoxia (CIH) condition and its action mechanism were investigated. Thirty healthy 8-week old Sprague-Dawley (SD) male rats were randomly divided into three gr......
Experimental study on treatment of glioma by embyonic neural stem cell transplnation in rats
Journal of Tongji Medical University - Tập 27 - Trang 571-575 - 2007
The neural stem cells in Wistar rats were cultured in vitro, purified, and transplanted into C6 glioma model in order to observe their biological characters and provide a basic foundation for treatment of neurological diseases by neural stem cell transplantation. The cells at hippocampal area from gestation 15-day rats were cultured in vitro, and frozen and preserved in liquid nitrogen. C6 tumor-b......
Effect of Wumeiwan on cytokines TNF-α, IL-6, IL-8, IL-10 and expression of NF-κBp65 in rats with ulcerative colitis
Journal of Tongji Medical University - Tập 29 - Trang 650-654 - 2009
The effects of Wumeiwan (WMW) on TNF-α, IL-6, IL-8, IL-10 and NF-κBp65 in rats with ulcerative colitis (UC) were investigated, the curative effectiveness of WMW vs salicylazosulfapyridine (SASP) was compared, and the action mechanism was analyzed. Fifty-Six Sprague-Dawley (SD) rats were randomly divided into four groups (n=14 in each group, with equal ratio of male and female): normal control grou......
Studies on the calcium antagonistic action of tetrandrine: XI. Effects of tetrandrine and calcium chloride on the impedance cardiogram of anesthetized canines
Journal of Tongji Medical University - Tập 6 - Trang 1-5 - 1986
Tetrandrine (Tet) 10 mg/kg or verapamil (Ver) 0.4 mg/kg i.v. decreased cardiac contractility as shown by the lowering of dZ/dtmax, prolongation of Q-Z interval and decrease of Heather index in anesthetized dogs. The pump function parameters of the heart: cardiac output, cardiac index, stroke volume, stroke index and time tension index were reduced concomitantly. Since both drugs decreased heart ra......
Studies on the calcium antagonistic action of tetrandrine: XIV. Influence of tetrandrine and verapamil on hemodynamic action of ouabain in guinea pig
Journal of Tongji Medical University - Tập 7 - Trang 80-83 - 1987
After pretreatment with verapamil (Ver) and tetrandrine (Tet), the amount of ouabain required to induce the onset and peaking of inotropic effect as well as toxic reaction was increased, while peak value of positive inotropic effect was unaltered. Neither the toxicity of ouabain nor its margin of safety was changed, but preventive and therapeutic action of Tet and Ver on ouabain-induced arrhythmia......
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