Journal of Tongji Medical University
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Sắp xếp:
1,2,3,4,6-penta-O-galloyl-β-D-glucose protects PC12 Cells from MPP+-mediated cell death by inducing heme oxygenase-1 in an ERK- and Akt-dependent manner
Journal of Tongji Medical University - Tập 32 Số 5 - Trang 737-745 - 2012
Preliminary studies on the application of retinal thickness analyzer in the diagnosis of glaucoma
Journal of Tongji Medical University - Tập 20 - Trang 257-260 - 2000
The patients with glaucoma underwent the examination of retinal thickness analyzer (RTA) to explore the diagnostic value of RTA in glaucoma. The retina of 6 mm × 6 mm size (approximately 20°, centered on the macula) at the posterior pole was scanned by using RTA to obtain the images in 35 eyes of 22 patients with glaucoma. The images were processed by using SAS software package. The retinal thickn...... hiện toàn bộ
Inhibitory effects of parthenolide on the activity of NF-κB in multiple myeloma via targeting TRAF6
Journal of Tongji Medical University - Tập 35 - Trang 343-349 - 2015
This study examined the mechanism of the inhibitory effect of parthenolide (PTL) on the activity of NF-κB in multiple myeloma (MM). Human multiple myeloma cell line RPMI 8226 cells were treated with or without different concentrations of PTL for various time periods, and then MTT assay was used to detect cell proliferation. Cell cycle and apoptosis were flow cytometrically detected. The level of p...... hiện toàn bộ
Transcription and translation of dickkopf-1 in endometrium of pregnant mice during the peri-implantation period
Journal of Tongji Medical University - Tập 24 - Trang 625-627 - 2004
To study the expression of Dickkopf-1 (DKK-1) in endometrium of pregnant mice during the peri implantation period and the role of DKK-1 during the embryo implantation in mice. Immunohistochemical technique was employed to determine the location of DKK-1 protein in endometrium, and semiquantitative reverse transcriptase polymerase chain reaction (RT-PCR) was utilized to determine the levels of DKK-...... hiện toàn bộ
The observation of complement activation and polymorphonuclear neutrocytopenia during cardiopulmonary bypass
Journal of Tongji Medical University - Tập 16 - Trang 99-102 - 1996
By determining the plasma levels of C3, C4, factor B and polymorphonuclear neutrophils (PMNs) of the patients who received CPB, the path of complement activation and changes of PMNs were studied. The results suggest that complement system was activated through alternative pathway during CPB and was activated through classic pathway after CPB. The anaphylatoxin, the products of complement activatio...... hiện toàn bộ
Are cancer stem cells the sole source of tumor?
Journal of Tongji Medical University - Tập 34 - Trang 621-625 - 2014
Tumors are believed to consist of a heterogeneous population of tumor cells originating from rare cancer stem cells (CSCs). However, emerging evidence suggests that tumor may also originate from non-CSCs. To support this viewpoint, we are here to present definitive evidence indicating that the number of tumorigenic tumor cells is greater than that of CSCs in tumor, and tumor can also derive from n...... hiện toàn bộ
Implication of expression of Nanog in prostate cancer cells and their stem cells
Journal of Tongji Medical University - Tập 32 - Trang 242-246 - 2012
Recent studies suggested that the prostate cancer may arise from prostate cancer stem cells that share some same characteristics with normal stem cells. The purpose of this study was to detect the differences of Nanog expression between PC3 prostate cancer cell line and its tumor stem cells, and the relationship was preliminarily examined between Nanog and prostate cancer and its tumor stem cells....... hiện toàn bộ
Effect of cardiopulmonary bypass on the specific immunity of the host
Journal of Tongji Medical University - Tập 13 - Trang 231-233 - 1993
T cell subsets and immunoglobulin (Ig) were observed sequentially with the OKT monoclonal antibodies rosette test and the rate scattering turbidimetry in 13 patients who underwent open heart surgery under cardiopulmonary bypass (CPB) for rheumatic heart diseases (RHD) and congenital heart diseases (CHD), before and after operation. Compared with preoperative values, in the early period after CPB, ...... hiện toàn bộ
Association of polymorphisms in angiotensin II receptor genes with aldosterone-producing adenoma
Journal of Tongji Medical University - Tập 31 - Trang 301-305 - 2011
This study examined the association of polymorphisms in angiotensin II receptor genes (AT
1
R and AT
2
R) with the risk for aldosterone-producing adenoma (APA) in a Chinese Han population. Four polymorphisms including rs5182 (573T/C) in exon 4, rs5186 (1166A/C) in 3′-untranslated region (3′-UTR) in AT
...... hiện toàn bộ
p38 MAPK regulates Th2 cytokines release in PBMCs in allergic rhinitis rats
Journal of Tongji Medical University - Tập 30 - Trang 222-225 - 2010
Th2 cytokines play a pivotal role in the pathogenesis of allergic rhinitis. To investigate the effect of p38 mitogen-activated protein kinase (MAPK) on the production of Th2 cytokines such as IL-4 and IL-5 in allergic rhinitis, a model of allergic rhinitis was established in SD rats. The expression level of p38 MAPK mRNA in PBMCs was detected by means of real time quantitative RT-PCR. The p38 MAPK...... hiện toàn bộ
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