Journal of Tongji Medical University

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Antisense oligodeoxynucleotide inhibits expression of recombinant porcine follicle-stimulating hormone receptor
Journal of Tongji Medical University - Tập 19 - Trang 175-180 - 1999
Zhu Changhong, Mark D. Nixon, Wang Yifang, Andrew R. LaBarbera
To assess the role of follicle-stimulating hormone receptor (FSHR) gene expression in regulating expression of FSHR protein in the plasma membrane, the effects of a porcine FSHR cDNA antisense oligodeoxynucleotide (ODN) on FSHR mRNA levels and 125I-FSH binding were determined in Chinese hamster ovary cells expression recombinant porcine FSHR (pFSHR-CHO cells). An 18-mer phosphorothioate-endcapped ...... hiện toàn bộ
Effect of NADPH oxidase inhibitor apocynin on the expression of hypoxia-induced factor-1α and endothelin-1 in rat carotid body exposed to chronic intermittent hypoxia
Journal of Tongji Medical University - - 2013
Xue Liu, Yan Deng, Jin Shang, Xiu-hong Yang, Kui Liu, Hui-guo Liu, Yong-jian Xu
The effects of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase inhibitor apocynin on the enhanced hypoxia induced factor-1α (HIF-1α) and endothelin-1 (ET-1) expression, elevated systolic blood pressure under chronic intermittent hypoxia (CIH) condition and its action mechanism were investigated. Thirty healthy 8-week old Sprague-Dawley (SD) male rats were randomly divided into three gr...... hiện toàn bộ
Effect of Wumeiwan on cytokines TNF-α, IL-6, IL-8, IL-10 and expression of NF-κBp65 in rats with ulcerative colitis
Journal of Tongji Medical University - Tập 29 - Trang 650-654 - 2009
Heng Fan, Lin Shen, Qing Tang, Pengcheng Xiong, Zhexing Shou, Yi Liao, Li Liang, Xiaoyan Chen
The effects of Wumeiwan (WMW) on TNF-α, IL-6, IL-8, IL-10 and NF-κBp65 in rats with ulcerative colitis (UC) were investigated, the curative effectiveness of WMW vs salicylazosulfapyridine (SASP) was compared, and the action mechanism was analyzed. Fifty-Six Sprague-Dawley (SD) rats were randomly divided into four groups (n=14 in each group, with equal ratio of male and female): normal control grou...... hiện toàn bộ
Effects of cigarette smoking on the function of metabolizing arachidonic acid and angiotensin I in the isolated perfused rat lungs
Journal of Tongji Medical University - Tập 12 Số 4 - Trang 201-204 - 1992
Xiao Yu, Jin Xian-rong, Wang Di-xun
Untersuchungen zur Wirkung von Dichroa febrifuga L. auf chloroquinsensible und chloroquinresistente Malariaparasiten
Journal of Tongji Medical University - Tập 6 Số 2 - Trang 112-115 - 1986
Can-xi, Zhao
Extrakt von Dichroa febrifuga L. wurde in vivo und in vitro auf Antimalariawirkung untersucht. Es zeigte sich, da\ Dichroa febrifuga L. bei experimentellen Malariainfektionen (P. berghei, Sprague-Dawley-Ratten) eine mit Chloroquin vergleichbare Wirkung besitzt. Dichroa febrifuga L. war auch gegen eine hoch chloroquinresistente P. berghei-Zell-Linie gut wirksam. Die Wirkung von Dichroa febrifuga L....... hiện toàn bộ
Role of nitric oxide and nitric oxide synthases in ischemia-reperfusion injury in rat organotypic hippocampus slice
Journal of Tongji Medical University - Tập 25 - Trang 619-621 - 2005
Meng Xianfang, Shi Jing, Liu Xiaochun, Zhang Jing, Sun Ning
To investigate the effects of ischemia-reperfusion on the levels of nitric oxide and nitric oxide synthase isoforms (nNOS and iNOS), rat organotypic hippocampus slice were cultured in vitro and subjected to ischemia by oxygen-glucose deprivation (OGD) for 30 min and then placed in the normal culture condition. The ischemia-reperfusion produced a time-dependent increase in nitrite levels in the cul...... hiện toàn bộ
Effects of propofol on the mRNA expression of toll-like receptor 4 in BV-2 cells during mimic ischemia-reperfusion injury in vitro
Journal of Tongji Medical University - Tập 28 - Trang 711-713 - 2008
Qing Zhang, Peng Sun, Shihai Zhang, Yuan Tian, Jinghui Zhang
This study investigated the effects of propofol on the mRNA expression of Toll-like receptor-4 (TLR4) in BV-2 cells during mimic ischemia-reperfusion (I/R) injury in vitro. BV-2 cells, a mouse microglia line, were cultured and divided into 4 groups at random: control group (group C), ischemia/reperfusion group (group I/R), low-dose propofol (25 μmol/L) intervention group (group PF25) and high-dose...... hiện toàn bộ
Transcription and translation of dickkopf-1 in endometrium of pregnant mice during the peri-implantation period
Journal of Tongji Medical University - Tập 24 - Trang 625-627 - 2004
Zhang Hanwang, Lai Qiaohong
To study the expression of Dickkopf-1 (DKK-1) in endometrium of pregnant mice during the peri implantation period and the role of DKK-1 during the embryo implantation in mice. Immunohistochemical technique was employed to determine the location of DKK-1 protein in endometrium, and semiquantitative reverse transcriptase polymerase chain reaction (RT-PCR) was utilized to determine the levels of DKK-...... hiện toàn bộ
Prognostic factors for patients after curative resection for proximal gastric cancer
Journal of Tongji Medical University - Tập 30 - Trang 530-535 - 2010
Donghui Zhao, Huimian Xu, Kai Li, Zhe Sun
The factors influencing the long-term survival of patients with proximal gastric cancer (PGC) after curative resection were investigated. Data from 171 patients who underwent curative resection for PGC were retrospectively analyzed. The patients were grouped according to the clinicopathological factors and operative procedures. The tumor depth (T stage) and lymph node metastasis (pN stage) were gr...... hiện toàn bộ
Diagnosis and treatment of 42 cases of multiple injuries with pancreatic injury
Journal of Tongji Medical University - Tập 28 Số 1 - Trang 84-86 - 2008
C. Mba, Xiangjun Bai, Zhanfei Li, Zhaohui Tang, Wenxuan Wang, Zhen Yang
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