Deregulated NLRP3 and NLRP1 Inflammasomes and Their Correlations with Disease Activity in Systemic Lupus ErythematosusJournal of Rheumatology - Tập 41 Số 3 - Trang 444-452 - 2014
Qingrui Yang, Chengcheng Yu, Zhaowen Yang, Qing Wei, Kun Mu, Ying Zhang, Wei Zhao, Xiaofeng Wang, Wanwan Huai, Lihui Han
Objective.NOD-like receptor family, pyrin domain containing 3 and 1 (NLRP3 and NLRP1) inflammasomes are molecular platforms that sense the damage or danger signals of cells. We investigated whether NLRP3/NLRP1 inflammasomes are involved in the pathogenesis and progression of systemic lupus erythematosus (SLE).Meth...... hiện toàn bộ
Raynaud’s Phenomenon and Plasma Endothelin: Correlations with Capillaroscopic Patterns in Systemic SclerosisJournal of Rheumatology - Tập 36 Số 6 - Trang 1235-1239 - 2009
Alberto Sulli, Stefano Soldano, Carmen Pizzorni, P. Montagna, M E Secchi, Barbara Villaggio, B. Seriolo, R. Brizzolara, Maurizio Cutolo
Objective.We evaluated endothelin (ET)-1 plasma levels and some clinical measures in patients with primary Raynaud’s phenomenon (PRP), and in patients with systemic sclerosis (SSc) and secondary RP (SRP), in the latter according to their different nailfold videocapillaroscopy (NVC) patterns of microangiopathy (early, active, and late)....... hiện toàn bộ
Bộ lãnh thổ cốt lõi OMERACT-OARSI cho việc đo lường trong các thử nghiệm lâm sàng bệnh thoái hóa khớp hông và/hoặc đầu gối Dịch bởi AI Journal of Rheumatology - Tập 46 Số 8 - Trang 981-989 - 2019
Toby O. Smith, Gillian Hawker, David J. Hunter, Lyn March, Maarten Boers, Beverley Shea, Robin Christensen, Françis Guillemin, Caroline B. Terwee, Paula Williamson, Susanna Dodd, Ewa M. Roos, Richard F. Loeser, Thomas J. Schnitzer, M. Kloppenburg, Tuhina Neogi, C. Ladel, Gurdyal Kalsi, Ulrike Kaiser, T. Buttel, A. E. Ashford, Ali Mobasheri, Nigel Arden, Alan H. Tennant, M. Hochberg, Maarten de Wit, Peter Tugwell, Philip G. Conaghan
Mục tiêu.Cập nhật bộ lãnh thổ cốt lõi OMERACT-OARSI (Các biện pháp kết quả trong Nghiên cứu Khớp-Osteoarthritis Research Society International) năm 1997 cho các thử nghiệm lâm sàng trong bệnh thoái hóa khớp hông và/hoặc đầu gối.Phương pháp.Một đánh giá ban đầu về cơ sở dữ liệu COMET của các bộ...... hiện toàn bộ
MicroRNA-mediated Regulation of Mucin-type O-glycosylation Pathway: A Putative Mechanism of Salivary Gland Dysfunction in Sjögren SyndromeJournal of Rheumatology - Tập 46 Số 11 - Trang 1485-1494 - 2019
Alessia Gallo, Serena Vella, Fabio Tuzzolino, Nicola Cuscino, Antonella Cecchettini, Francesco Ferro, Marta Mosca, Ilias Alevizos, Stefano Fedele, Pier Giulio Conaldi, Chiara Baldini
Objective.To investigate microRNA (miRNA) that is potentially implicated in primary Sjögren syndrome (pSS)–related salivary hypofunction in labial salivary glands and to study miRNA-mediated mechanisms underlying oral dryness and altered rheology, focusing on the mucin O-glycosylation pathway.Methods....... hiện toàn bộ
Systematic Review of Treatments for Psoriatic Arthritis: 2014 Update for the GRAPPAJournal of Rheumatology - Tập 41 Số 11 - Trang 2273-2276 - 2014
Laura C. Coates, Arthur Kavanaugh, Christopher T. Ritchlin
Psoriatic arthritis (PsA) is a chronic systemic inflammatory disorder characterized by the association of arthritis and periarticular inflammation in patients with psoriasis. In addition to a heterogeneous and variable clinical course, PsA is complex and multifaceted and may include prominent involvement in the peripheral and axial diarthrodial joints, the skin and nails, and in periarticu...... hiện toàn bộ
Reliability and Clinically Important Improvement Thresholds for Osteoarthritis Pain and Function Scales: A Multicenter StudyJournal of Rheumatology - Tập 41 Số 3 - Trang 509-515 - 2014
Jasvinder A. Singh, Ruili Luo, Gene Landon, María E. Suarez‐Almazor
Objective.To assess the reliability and clinically meaningful thresholds of intermittent and constant osteoarthritis pain (ICOAP) score, the Knee injury and Osteoarthritis Outcome Score Physical function Short-form (KOOS-PS), the Hip disability and Osteoarthritis Outcome Score Physical function Short-form (HOOS-PS), and the Quality of life subscales of HO...... hiện toàn bộ