The Novel γ Secretase Inhibitor N-[cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) Reduces Amyloid Plaque Deposition without Evidence of Notch-Related Pathology in the Tg2576 MouseJournal of Pharmacology and Experimental Therapeutics - Tập 320 Số 2 - Trang 552-558 - 2007
Jonathan D. Best, David W. Smith, Michael Reilly, Ruth O’Donnell, Huw D. Lewis, Semantha Ellis, Neil Wilkie, Thomas W. Rosahl, Philippe A Laroque, Christine Boussiquet-Leroux, Ian Churcher, John Atack, Timothy Harrison, Mark S. Shearman
The 5-Hydroxytryptamine4 Receptor Agonists Prucalopride and PRX-03140 Increase Acetylcholine and Histamine Levels in the Rat Prefrontal Cortex and the Power of Stimulated Hippocampal θ OscillationsJournal of Pharmacology and Experimental Therapeutics - Tập 341 Số 3 - Trang 681-691 - 2012
David E. Johnson, Elena M. Drummond, Sarah Grimwood, Aarti Sawant‐Basak, Emily Miller, Elaine Tseng, Laura McDowell, Michelle Vanase‐Frawley, Katherine Fisher, David M. Rubitski, K J Stutzman-Engwall, Robin T. Nelson, W. Elliott Horner, Roxanne Gorczyca, Mihály Hajós, Chester J. Siok