Journal of Periodontology

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Evaluation of Pluronic Polyols as Carriers for Grafting Materials: Study in Rat Calvaria Defects
Journal of Periodontology - Tập 73 Số 2 - Trang 191-197 - 2002
Edward B. Fowler, Michael F. Cuenin, Steven D. Hokett, Mark E. Peacock, James C. McPherson, Thomas R. Dirksen, Mohamed Sharawy, Michael A. Billman
Background: Pluronic polyols are a family of non‐ionic surfactants currently used as drug carriers for antibiotic, anti‐inflammatory, and anti‐neoplastic agents. Therapeutic administration of non‐ionic surface‐active agents is known to facilitate early collagen synthesis and microcirculation, thus promoting wound healing. The purpose of this study was to determine th...... hiện toàn bộ
The Causes of Early Implant Bone Loss: Myth or Science?
Journal of Periodontology - Tập 73 Số 3 - Trang 322-333 - 2002
Tae‐Ju Oh, Joongkyo Yoon, Carl E. Misch, Hom‐Lay Wang
The success of dental implants is highly dependent on integration between the implant and intraoral hard/soft tissue. Initial breakdown of the implant‐tissue interface generally begins at the crestal region in successfully osseointegrated endosteal implants, regardless of surgical approaches (submerged or nonsubmerged). Early crestal bone loss is often observed after the first...... hiện toàn bộ
Antigenicity of Freeze‐Dried Cortical Bone Allograft in Human Periodontal Osseous Defects
Journal of Periodontology - Tập 59 Số 6 - Trang 394-397 - 1988
J. Bryan Quattlebaunr, James T. Mellonig, Nancy F. Hensel
The purpose of this investigation was to determine whether donor‐specific anti‐HLA antibodies could be detected against freeze‐dried cortical bone allograft (FDBA) placed in human periodontal osseous defects. Twenty patients with multiple periodontal bony defects amenable to treatment in two allografting procedures were enrolled. No patient had preexisting anti‐HLA antib...... hiện toàn bộ
Osteogenesis Enhanced by Chitosan (Poly‐N‐Acetyl Glucosaminoglycan) In Vitro
Journal of Periodontology - Tập 67 Số 11 - Trang 1170-1175 - 1996
Perry R. Klokkevold, Lorese Vandemark, E. Barrie Kenney, George W. Bernard
Chitosan, with a chemical structure similar to hyaluronic acid, has been implicated as a wound healing agent. The purpose of this research was to evaluate the effect of chitosan on Osteoblast differentiation and bone formation in vitro. Mesenchymal stem cells were harvested from fetal Swiss Webster mice calvariae prior to osteoblast differentiation and calcification (12 ...... hiện toàn bộ
Effect of Topical Administration of Monosodium Olpadronate on Experimental Periodontitis in Rats
Journal of Periodontology - Tập 77 Số 1 - Trang 1-6 - 2006
Juan A Goya, Hugo A. Paez, Patricia Mandalunis
Background: Periodontitis is characterized by gingival inflammation, periodontal pocket formation, and bacterial plaque that lead to alveolar bone destruction. Research studies have recently begun to evaluate the effect of antiresorptive agents using experimental models of periodontitis. Bisphosphonates are the most frequently tested antiresorptive agents; their main...... hiện toàn bộ
Evaluation of Human Recession Defects Treated with Coronally Advanced Flaps and Either Enamel Matrix Derivative or Connective Tissue. Part 1: Comparison of Clinical Parameters
Journal of Periodontology - Tập 74 Số 8 - Trang 1110-1125 - 2003
Shelley McGuire, Martha E. Nunn
Background: Recession defects around teeth have been treated with a variety of surgical techniques. Most of the literature suggests that the subepithelial connective tissue graft has the highest percentage of mean root coverage with the least variability. Previous studies have demonstrated that enamel matrix derivative (EMD) has the ability to improve clinical parame...... hiện toàn bộ
Halitosis Measurement by an Industrial Sulphide Monitor
Journal of Periodontology - Tập 62 Số 8 - Trang 487-489 - 1991
Mel Rosenberg, Idit Septon, Ilana Eli, Ronit Bar‐Ness, Ilana Gelernter, Shmuel Brenner, J. Gabbay
Previous studies have established that hydrogen sulphide and mercaptans are the primary components of halitosis (bad breath). In the present investigation, we report a simple, rapid technique for measurement of halitosis‐related sulphides. The technique is based on a portable instrument generally used for environmental safety applications. Seventy‐five volunteers were me...... hiện toàn bộ
Bacterial Invasion of Periodontal Tissues in Advanced Periodontitis in Humans
Journal of Periodontology - Tập 55 Số 10 - Trang 567-573 - 1984
A Manor, M. Lebendiger, A. Shifter, H. Tovel
Bacterial invasion of the pocket epithelium and underlying connective tissue was found in seven cases of advanced human periodontitis. Four cases showed invasion of the epithelium as well as the connective tissue while in the other three cases bacterial invasion was limited to the pocket epithelium. The microorganisms observed included cocci, rods, filaments, fusiforms a...... hiện toàn bộ
Assessment of Risk for Periodontal Disease. II. Risk Indicators for Alveolar Bone Loss
Journal of Periodontology - Tập 66 Số 1 - Trang 23-29 - 1995
Sara G. Grossi, Robert J. Genco, Eli E. Machtet, Alex Ho, Gary G. Koch, Robert G. Dunford, Joseph J. Zambon, E. Hausmann
This study examined the risk indicators for alveolar bone loss associated with periodontal infection. A cross‐section of 1,361 subjects aged 25 to 74 years, from Erie County, NY were evaluated for interproximal alveolar bone loss and potential explanatory variables including age, gender, history of systemic diseases, smoking, and presence of 8 subgingival bacteria. Inter...... hiện toàn bộ
Nifedipine Induces Gingival Epithelial Hyperplasia in Rats Through Inhibition of Apoptosis
Journal of Periodontology - Tập 73 Số 8 - Trang 861-867 - 2002
Yasuki Shimizu, Masatoshi Kataoka, Hiroyuki Seto, Jun‐ichi Kido, Toshihiko Nagata
Background: Nifedipine is used as a long‐acting vasodilator; one of its side effects is gingival overgrowth, characterized by an accumulation of collagenous components within the gingival connective tissue and epithelial hyperplasia with elongated, branched rete pegs penetrating into the connective tissue. We investigated the effect of nifedipine on apoptosis of ging...... hiện toàn bộ
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