Comparison of Freeze–Dried Bone Allograft and Porous Hydroxylapatite in Human Periodontal Defects

Journal of Periodontology - Tập 60 Số 5 - Trang 231-237 - 1989
Joseph D. Barnett1, James T. Mellonig2, Jonathan L. Gray3, Herbert J. Towle3
1Lieutenant Commander, DC, USN, Branch Dental Clinic, Box D, Naval Station, Mayport, FL 32228.
2Captain, DC, USN, Periodontics Department, Naval Dental School, Naval Dental Clinic, Naval Medical Command, National Capital Region, Bethesda, MD 20814.
3Captain, DC, USN, Periodontics Department, NDS, Bethesda, MD. The opinions or assertions contained in this article are the private ones of the writers and are not to be construed as official or as reflecting the views of the Department of the Navy, Department of Defense, or the U.S. Government.

Tóm tắt

This study was conducted to clinically compare the efficacy of freeze‐dried bone allograft (FDBA) and porous hydroxylapatite granules. Nineteen pairs of intraosseous defects were grafted in seven patients. One defect of each pair was implanted with FDBA, the other with granular porous hydroxylapatite. Matching defects were treated similarly in all other aspects. Evaluations were based on both preoperative and postoperative measurements from a fixed reference point, standardized radiographs, surgical osseous measurements, and histology of degranulated tissues. Grafted sites were reentered 6 to 11 months postsurgery. Results showed a mean osseous fill of 2.1 mm for FDBA versus 1.3 mm for granular porous hydroxylapatite (P =.07). A mean clinical attachment gain of 2.2 mm for FDBA versus 1.3 mm for granular porous hydroxylapatite (P <.05), and a mean decrease in probing depths of 3.0 mm for FDBA verses 1.4 mm for granular porous hydroxylapatite (P < 0.5) was found. FDBA was clinically indistinguishable from host bone, whereas porous hydroxylapatite appeared to be separated from host bone by soft tissue. The data and clinical findings suggested that FDBA may have some enhanced reparative potential when compared to granular porous hydroxylapatite in the treatment of periodontal defects in humans.

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Journal of Periodontology

Tập 60 Số 5

231-237

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