Journal of Ovarian Research

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Diagnostic workup for endometrioid borderline ovarian tumors (eBOT) requires histopathological evaluation of the uterus
Journal of Ovarian Research - Tập 14 - Trang 1-7 - 2021
Juliane Reichenbach, Elisa Schmoeckel, Sven Mahner, Fabian Trillsch
For young borderline ovarian tumor (BOT) patients, preservation of the uterus was incorporated as an accepted option into treatment guidelines. For the endometrioid subtype (eBOT) however, adequate histological evaluation is challenging and might be associated with synchronous endometrial disorders or misinterpreted as spread from uterine primaries. We report the cases of two young patients with e...... hiện toàn bộ
Evaluation of the value of preoperative CYFRA21-1 in the diagnosis and prognosis of epithelial ovarian cancer in conjunction with CA125
Journal of Ovarian Research - Tập 12 - Trang 1-8 - 2019
Chunjing Jin, Minfeng Yang, Xueqiao Han, Haidan Chu, Yan Zhang, Meihong Lu, Zhonghui Wang, Xinxin Xu, Wenwen Liu, Feng Wang, Shaoqing Ju
Growing evidence indicates that the tumor biomarker cytokeratin 19 fragment (CYFRA21-1) is significant for a variety of cancers. However, its role in epithelial ovarian cancer (EOC) has rarely been reported. In this study, a receiver operating characteristic (ROC) curve was utilized to estimate the diagnostic efficiency of CYFRA21-1. The correlation between the CYFRA21-1 level and prognosis was an...... hiện toàn bộ
No evidence for a diminished ovarian reserve among patients with hypertensive disorders of pregnancy: a case control study
Journal of Ovarian Research - Tập 17 Số 1 - Trang 1-6 - 2024
van Bree, Bo E., Jorissen, Laura M., Pattinaja, Désirée A.P.M., Bons, Judith A.P., Spaanderman, Marc E.A., Valkenburg, Olivier, van Golde, Ron J.T.
Existing evidence suggests a relation between cardiovascular dysfunction and diminished ovarian reserve. While it is known that pre-existent cardiovascular dysfunction is also associated with the development of preeclampsia (PE) during pregnancy, we hypothesize that signs of diminished ovarian reserve may occur more frequently among women with a history of hypertensive disorders of pregnancy (HDP)...... hiện toàn bộ
Health related quality of life and psychological parameters in different polycystic ovary syndrome phenotypes: a comparative cross-sectional study
Journal of Ovarian Research - Tập 14 - Trang 1-9 - 2021
Bahadori Fatemeh, Jahanian Sadatmahalleh Shahideh, Mirzaei Negin
Polycystic Ovary Syndrome (PCOS) is associated with high levels of phsychological implications and detriments to Quality of Life (QoL). The aim of this study was to assess Health- Related Quality of Life (HRQoL), depression, and anxiety in Iranian women with different PCOS phenotypes. The present observational, cross-sectional study was carried out on 239 PCOS women who were classified on the basi...... hiện toàn bộ
LncRNA DANCR counteracts premature ovarian insufficiency by regulating the senescence process of granulosa cells through stabilizing the interaction between p53 and hNRNPC
Journal of Ovarian Research - Tập 16 - Trang 1-14 - 2023
Di Sun, Yining Wang, Ningxia Sun, Zhongxin Jiang, Ziyuan Li, Liang Wang, Fu Yang, Wen Li
Premature ovarian insufficiency (POI) is one of the common women reproductive endocrine diseases which adversely impacts female fertility, but the etiology and pathogenesis still remain elusive. Recently increasing researches focus on the roles of lncRNA in POI. LncRNA DANCR was involved in cell differentiation and multiple cancers. It’s highly expressed in ovary while the role of DANCR in POI is ...... hiện toàn bộ
Role of protein tyrosine phosphatase receptor type M in epithelial ovarian cancer progression
Journal of Ovarian Research - Tập 16 - Trang 1-13 - 2023
Xiao Li, Wei Ding, Yang Rao, Pengpeng Qu
Epithelial ovarian cancer (EOC) is often diagnosed at advanced stages with low survival rates. Protein tyrosine phosphatase receptor type M (PTPRM) is involved in cancer development and progression; however, its role in EOC remains unclear. In this study,we aimed to detect PTPRM expression in ovarian epithelial tumors, analyze its relationship with the clinicopathological features and survival pro...... hiện toàn bộ
Effect of hysterectomy on ovarian function: a systematic review and meta-analysis
Journal of Ovarian Research -
Yibao Huang, Meng Wu, Chuqing Wu, Qingqing Zhu, Tong Wu, Xiaoran Zhu, Mingfu Wu, Shixuan Wang
Abstract Background Hysterectomy is one of the most frequently gynecologic surgeries performed in premenopausal women. Many premenopausal patients are unwilling to undergo hysterectomy due to the probable decreased ovarian function. The aim of this study is to determine the effect of hysterectomy on...... hiện toàn bộ
Sialylation of EGFR by the ST6Gal-I sialyltransferase promotes EGFR activation and resistance to gefitinib-mediated cell death
Journal of Ovarian Research - Tập 11 - Trang 1-11 - 2018
Colleen M. Britain, Andrew T. Holdbrooks, Joshua C. Anderson, Christopher D. Willey, Susan L. Bellis
The ST6Gal-I sialyltransferase is upregulated in numerous cancers, and high expression of this enzyme correlates with poor patient prognosis in various malignancies, including ovarian cancer. Through its sialylation of a select cohort of cell surface receptors, ST6Gal-I modulates cell signaling to promote tumor cell survival. The goal of the present study was to investigate the influence of ST6Gal...... hiện toàn bộ
Transvaginal ultrasound ovarian diathermy: sheep as an experimental model
Journal of Ovarian Research - Tập 5 - Trang 1-4 - 2012
Anita M Pimentel, Danielle Kobayashi, Lucia M Kliemann, Renato Franjdlich, Edison Capp, Helena VE Corleta
Some techniques of transvaginal ovarian drilling have been previously described. Nevertheless a monopolar transvaginal ovarian cauterization, that use the expertise and safety of transvaginal puncture for oocyte captation seems to be an easier and feasible approach. The aim of this study was to develop a minimally invasive ovarian cauterization technique under transvaginal ultrasound control, and ...... hiện toàn bộ
Anti-IGF-1R monoclonal antibody inhibits the carcinogenicity activity of acquired trastuzumab-resistant SKOV3
Journal of Ovarian Research - Tập 7 Số 1 - Trang 1-12 - 2014
Wang, Wei, Zhang, Yan, Lv, Ming, Feng, Jiannan, Peng, Hui, Geng, Jing, Lin, Zhou, Zhou, Tingting, Li, Xinying, Shen, Beifen, Ma, Yuanfang, Qiao, Chunxia
Antibody resistance, not only de novo but also acquired cases, usually exists and is related with lower survival rate and high risk of recurrence. Reversing the resistance often results in better clinical therapeutic effect. Previously, we established a trastuzumab-resistant ovarian cancer cell line, named as SKOV3-T, with lower HER2 and induced higher IGF-1R expression level to keep cell survival...... hiện toàn bộ
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