Journal of Ovarian Research
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Diagnostic workup for endometrioid borderline ovarian tumors (eBOT) requires histopathological evaluation of the uterus
Journal of Ovarian Research - Tập 14 - Trang 1-7 - 2021
For young borderline ovarian tumor (BOT) patients, preservation of the uterus
was incorporated as an accepted option into treatment guidelines. For the
endometrioid subtype (eBOT) however, adequate histological evaluation is
challenging and might be associated with synchronous endometrial disorders or
misinterpreted as spread from uterine primaries. We report the cases of two
young patients with e...
Evaluation of the value of preoperative CYFRA21-1 in the diagnosis and prognosis of epithelial ovarian cancer in conjunction with CA125
Journal of Ovarian Research - Tập 12 - Trang 1-8 - 2019
Growing evidence indicates that the tumor biomarker cytokeratin 19 fragment
(CYFRA21-1) is significant for a variety of cancers. However, its role in
epithelial ovarian cancer (EOC) has rarely been reported. In this study, a
receiver operating characteristic (ROC) curve was utilized to estimate the
diagnostic efficiency of CYFRA21-1. The correlation between the CYFRA21-1 level
and prognosis was an...
No evidence for a diminished ovarian reserve among patients with hypertensive disorders of pregnancy: a case control study
Journal of Ovarian Research - Tập 17 Số 1 - Trang 1-6 - 2024
Existing evidence suggests a relation between cardiovascular dysfunction and
diminished ovarian reserve. While it is known that pre-existent cardiovascular
dysfunction is also associated with the development of preeclampsia (PE) during
pregnancy, we hypothesize that signs of diminished ovarian reserve may occur
more frequently among women with a history of hypertensive disorders of
pregnancy (HDP)...
Health related quality of life and psychological parameters in different polycystic ovary syndrome phenotypes: a comparative cross-sectional study
Journal of Ovarian Research - Tập 14 - Trang 1-9 - 2021
Polycystic Ovary Syndrome (PCOS) is associated with high levels of
phsychological implications and detriments to Quality of Life (QoL). The aim of
this study was to assess Health- Related Quality of Life (HRQoL), depression,
and anxiety in Iranian women with different PCOS phenotypes. The present
observational, cross-sectional study was carried out on 239 PCOS women who were
classified on the basi...
LncRNA DANCR counteracts premature ovarian insufficiency by regulating the senescence process of granulosa cells through stabilizing the interaction between p53 and hNRNPC
Journal of Ovarian Research - Tập 16 - Trang 1-14 - 2023
Premature ovarian insufficiency (POI) is one of the common women reproductive
endocrine diseases which adversely impacts female fertility, but the etiology
and pathogenesis still remain elusive. Recently increasing researches focus on
the roles of lncRNA in POI. LncRNA DANCR was involved in cell differentiation
and multiple cancers. It’s highly expressed in ovary while the role of DANCR in
POI is ...
Role of protein tyrosine phosphatase receptor type M in epithelial ovarian cancer progression
Journal of Ovarian Research - Tập 16 - Trang 1-13 - 2023
Epithelial ovarian cancer (EOC) is often diagnosed at advanced stages with low
survival rates. Protein tyrosine phosphatase receptor type M (PTPRM) is involved
in cancer development and progression; however, its role in EOC remains unclear.
In this study,we aimed to detect PTPRM expression in ovarian epithelial tumors,
analyze its relationship with the clinicopathological features and survival
pro...
MUC4 stabilizes HER2 expression and maintains the cancer stem cell population in ovarian cancer cells
Journal of Ovarian Research - Tập 4 Số 1 - 2011
Abstract Background Recent evidence has suggested that the capability of cancer
to grow, propagate and relapse after therapy is dependent on a small subset of
the cell population within the tumor, called cancer stem cells. Therefore, this
subpopulation of cells needs to be targeted with different approaches by
identification of unique stem-cell specific target antigens. One of the well
known tumor...
Optimal parameters for determining the LH surge in natural cycle frozen-thawed embryo transfers
Journal of Ovarian Research - Tập 10 - Trang 1-7 - 2017
There is no consensus on the exact parameters that define the LH surge for
natural cycle frozen-thawed embryo transfers (NC-FET). Accurately determining
the LH surge would affect the timing, and subsequently the success rates, of
embryo transfer. Therefore, the aim of this study was to delineate the optimal
levels and relationship for luteinizing hormone (LH) and estradiol in an effort
to optimall...
Effect of hysterectomy on ovarian function: a systematic review and meta-analysis
Journal of Ovarian Research -
Abstract Background Hysterectomy is one of the most frequently gynecologic
surgeries performed in premenopausal women. Many premenopausal patients are
unwilling to undergo hysterectomy due to the probable decreased ovarian
function. The aim of this study is to determine the effect of hysterectomy on
ovarian function. Methods A meta-analysis has been reported in line with the
Preferred Reporting It...
Exosomal miR-1290 is a potential biomarker of high-grade serous ovarian carcinoma and can discriminate patients from those with malignancies of other histological types
Journal of Ovarian Research - Tập 11 - Trang 1-10 - 2018
microRNAs (miRNAs) stably exist in circulating blood encapsulated in
extracellular vesicles such as exosomes; therefore, serum miRNAs have the
potential to serve as novel cancer biomarkers. New diagnostic markers to detect
high grade serous ovarian cancer (HGSOC) are urgently needed. The aim of this
study was to identify miRNAs specific to HGSOC and analyze whether serum miRNA
can discriminate HGS...
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