Journal of Orthopaedic Surgery and Research
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Comparison of unilateral and bilateral polymethylmethacrylate-augmented cannulated pedicle screw fixation for the management of lumbar spondylolisthesis with osteoporosis
Journal of Orthopaedic Surgery and Research - Tập 15 - Trang 1-9 - 2020
Cannulated pedicle screw (CPS) augmented by polymethylmethacrylate (PMMA) can achieve satisfactory clinical efficacy in the treatment of lumbar spondylolisthesis with osteoporosis. However, accurate application of CPSs will help to avoid the difficulty of screw revision and reduce the incidence of PMMA-related complications. This study aimed to investigate the mid-term efficacy of CPS compared to ......
Use of Tranexamic acid is a cost effective method in preventing blood loss during and after total knee replacement
Journal of Orthopaedic Surgery and Research - - 2011
Allogenic blood transfusion in elective orthopaedic surgery is best avoided owing to its associated risks. Total knee replacement often requires blood transfusion, more so when bilateral surgery is performed. Many strategies are currently being employed to reduce the amount of peri-operative allogenic transfusions. Anti-fibrinolytic compounds such as aminocaproic acid and tranexamic acid have been......
Correlation between C-reactive protein and postoperative mortality in patients undergoing hip fracture surgery: a meta-analysis
Journal of Orthopaedic Surgery and Research - Tập 18 - Trang 1-9 - 2023
Hip fracture is a common but devastating disease with a high mortality rate in the older adult population. C-reactive protein (CRP) is a predictor of the prognosis in many diseases, but its correlations with patient outcomes following hip fracture surgery remain unclear. In this meta-analysis, we investigated the correlation between perioperative CRP level and postoperative mortality in patients u......
Changes in leg pain after bilateral fasciotomy to treat chronic compartment syndrome: a case series study
Journal of Orthopaedic Surgery and Research - - 2013
Intracompartmental pressure (ICP) as the diagnostic gold standard in the management of chronic compartment syndrome (CCS) is debated. We present a diagnostic protocol in which the decision to operate can be based upon clinical findings alone. The aim of this study was to examine whether patients who underwent surgery for CCS based on clinical findings experienced significant long-term pain relief.......
Knockdown of CD44 inhibits proliferation, migration and invasion of osteosarcoma cells accompanied by downregulation of cathepsin SAbstract
Background
Osteosarcoma (OS) is a malignant bone tumour of mesenchymal origin. These tumours are characterised by rich vascularisation, therefore promoting rapid proliferation and facilitating metastasis. CD44 has been reported to be involved in OS, but its role and molecular mechanisms in ... ...
Journal of Orthopaedic Surgery and Research - Tập 17 Số 1
Several first-line anti-hypertensives act on fibrosarcoma progression and PD1ab blockade therapyAbstract
Purpose
Patients are typically diagnosed with both hypertension and fibrosarcoma. Medical oncologists must prescribe suitable anti-hypertensive medications while considering anti-tumor drugs. Recently, immunotherapy has become prominent in cancer treatment. Nonetheless, it is unknown what r... ...
Journal of Orthopaedic Surgery and Research -
The importance of reaming the posterior femoral cortex before inserting lengthening nails and calculation of the amount of reaming
Journal of Orthopaedic Surgery and Research - Tập 11 - Trang 1-8 - 2016
Lengthening nails have been used to correct limb length discrepancy caused by different etiologies, as well as for post-traumatic reasons. Two important lengthening nail-related complications are damage to the distraction mechanism and femoral fractures around the nail tip. As a result of the curved anatomy of the femur, straight nails impinge on the anterior cortex. Therefore, proper reshaping of......
Prognostic value of p16, p53, and pcna in sarcoma and an evaluation of immune infiltration
Journal of Orthopaedic Surgery and Research - Tập 17 - Trang 1-14 - 2022
p16, p53, and proliferating cell nuclear antigen (pcna) genes play significant roles in many chromatin modifications and have been found to be highly expressed in a variety of tumor tissues. Therefore, they have been used as target genes for some tumor therapies. However, the differential expressions of the p16, p53, and pcna genes in human sarcomas and their effects on prognosis have not been wid......
Patient and surgical prognostic factors for inpatient functional recovery following THA and TKA: a prospective cohort study
Journal of Orthopaedic Surgery and Research - Tập 15 - Trang 1-19 - 2020
The introduction of enhanced recovery pathways has demonstrated both patient and organisational benefits. However, enhanced recovery pathways implemented for total hip arthroplasty (THA) and total knee arthroplasty (TKA) vary between health-care organisations, as do their measures of success, particularly patient-related outcomes. Despite inpatient functional recovery being essential for safe and ......
Lipofibromatous hamartoma of the median nerve
Journal of Orthopaedic Surgery and Research - Tập 5 - Trang 1-4 - 2010
Lipofibromatous hamartoma is a rare tumour of peripheral nerves which is characterised by an excessive infiltration of the epineurium and perineurium by fibroadipose tissue. To the best of our knowledge, only approximately 88 cases are reported in the literature. We report a rare case of lipofibromatous hamartoma of the median nerve causing secondary carpal tunnel syndrome in a 25 year old patient......
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