Journal of Orthopaedic Surgery and Research
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Comparison of unilateral and bilateral polymethylmethacrylate-augmented cannulated pedicle screw fixation for the management of lumbar spondylolisthesis with osteoporosis
Journal of Orthopaedic Surgery and Research - Tập 15 - Trang 1-9 - 2020
Cannulated pedicle screw (CPS) augmented by polymethylmethacrylate (PMMA) can
achieve satisfactory clinical efficacy in the treatment of lumbar
spondylolisthesis with osteoporosis. However, accurate application of CPSs will
help to avoid the difficulty of screw revision and reduce the incidence of
PMMA-related complications. This study aimed to investigate the mid-term
efficacy of CPS compared to ...
Use of Tranexamic acid is a cost effective method in preventing blood loss during and after total knee replacement
Journal of Orthopaedic Surgery and Research - - 2011
Allogenic blood transfusion in elective orthopaedic surgery is best avoided
owing to its associated risks. Total knee replacement often requires blood
transfusion, more so when bilateral surgery is performed. Many strategies are
currently being employed to reduce the amount of peri-operative allogenic
transfusions. Anti-fibrinolytic compounds such as aminocaproic acid and
tranexamic acid have been...
Correlation between C-reactive protein and postoperative mortality in patients undergoing hip fracture surgery: a meta-analysis
Journal of Orthopaedic Surgery and Research - Tập 18 - Trang 1-9 - 2023
Hip fracture is a common but devastating disease with a high mortality rate in
the older adult population. C-reactive protein (CRP) is a predictor of the
prognosis in many diseases, but its correlations with patient outcomes following
hip fracture surgery remain unclear. In this meta-analysis, we investigated the
correlation between perioperative CRP level and postoperative mortality in
patients u...
Changes in leg pain after bilateral fasciotomy to treat chronic compartment syndrome: a case series study
Journal of Orthopaedic Surgery and Research - - 2013
Intracompartmental pressure (ICP) as the diagnostic gold standard in the
management of chronic compartment syndrome (CCS) is debated. We present a
diagnostic protocol in which the decision to operate can be based upon clinical
findings alone. The aim of this study was to examine whether patients who
underwent surgery for CCS based on clinical findings experienced significant
long-term pain relief....
Knockdown of CD44 inhibits proliferation, migration and invasion of osteosarcoma cells accompanied by downregulation of cathepsin S
Journal of Orthopaedic Surgery and Research - Tập 17 Số 1
Abstract Background Osteosarcoma (OS) is a malignant bone tumour of mesenchymal
origin. These tumours are characterised by rich vascularisation, therefore
promoting rapid proliferation and facilitating metastasis. CD44 has been
reported to be involved in OS, but its role and molecular mechanisms in the
pathogenesis of the disease are not fully determined. Methods In this study, we
investigated the...
Several first-line anti-hypertensives act on fibrosarcoma progression and PD1ab blockade therapy
Journal of Orthopaedic Surgery and Research -
Abstract Purpose Patients are typically diagnosed with both hypertension and
fibrosarcoma. Medical oncologists must prescribe suitable anti-hypertensive
medications while considering anti-tumor drugs. Recently, immunotherapy has
become prominent in cancer treatment. Nonetheless, it is unknown what role
anti-hypertensive medications will play in immunotherapy. Methods We examined
the effects of six...
The importance of reaming the posterior femoral cortex before inserting lengthening nails and calculation of the amount of reaming
Journal of Orthopaedic Surgery and Research - Tập 11 - Trang 1-8 - 2016
Lengthening nails have been used to correct limb length discrepancy caused by
different etiologies, as well as for post-traumatic reasons. Two important
lengthening nail-related complications are damage to the distraction mechanism
and femoral fractures around the nail tip. As a result of the curved anatomy of
the femur, straight nails impinge on the anterior cortex. Therefore, proper
reshaping of...
Prognostic value of p16, p53, and pcna in sarcoma and an evaluation of immune infiltration
Journal of Orthopaedic Surgery and Research - Tập 17 - Trang 1-14 - 2022
p16, p53, and proliferating cell nuclear antigen (pcna) genes play significant
roles in many chromatin modifications and have been found to be highly expressed
in a variety of tumor tissues. Therefore, they have been used as target genes
for some tumor therapies. However, the differential expressions of the p16, p53,
and pcna genes in human sarcomas and their effects on prognosis have not been
wid...
Patient and surgical prognostic factors for inpatient functional recovery following THA and TKA: a prospective cohort study
Journal of Orthopaedic Surgery and Research - Tập 15 - Trang 1-19 - 2020
The introduction of enhanced recovery pathways has demonstrated both patient and
organisational benefits. However, enhanced recovery pathways implemented for
total hip arthroplasty (THA) and total knee arthroplasty (TKA) vary between
health-care organisations, as do their measures of success, particularly
patient-related outcomes. Despite inpatient functional recovery being essential
for safe and ...
Lipofibromatous hamartoma of the median nerve
Journal of Orthopaedic Surgery and Research - Tập 5 - Trang 1-4 - 2010
Lipofibromatous hamartoma is a rare tumour of peripheral nerves which is
characterised by an excessive infiltration of the epineurium and perineurium by
fibroadipose tissue. To the best of our knowledge, only approximately 88 cases
are reported in the literature. We report a rare case of lipofibromatous
hamartoma of the median nerve causing secondary carpal tunnel syndrome in a 25
year old patient...
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