Journal of Neuroscience
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Magnetoencephalography in Twins Reveals a Strong Genetic Determination of the Peak Frequency of Visually Induced Gamma-Band SynchronizationMany aspects of brain processing are intimately linked to brain rhythms. Essentially all classical brain rhythms, i.e., delta, theta, alpha, beta, and sleep waves, are highly heritable. This renders brain rhythms an interesting intermediate phenotype for cognitive and behavioral traits. One brain rhythm that has been particularly strongly linked to cognition is the gamma rhythm: it is invo... ... hiện toàn bộ
Journal of Neuroscience - Tập 32 Số 10 - Trang 3388-3392 - 2012
Unique Function of Kinesin Kif5A in Localization of Mitochondria in AxonsMutations in Kinesin proteins (Kifs) are linked to various neurological diseases, but the specific and redundant functions of the vertebrate Kifs are incompletely understood. For example, Kif5A, but not other Kinesin-1 heavy-chain family members, is implicated in Charcot-Marie-Tooth disease (CMT) and Hereditary Spastic Paraplegia (HSP), but the mechanism of its involvement in the progressi... ... hiện toàn bộ
Journal of Neuroscience - Tập 34 Số 44 - Trang 14717-14732 - 2014
A Lipid Gate for the Peripheral Control of PainCells in injured and inflamed tissues produce a number of proalgesic lipid-derived mediators, which excite nociceptive neurons by activating selective G-protein-coupled receptors or ligand-gated ion channels. Recent work has shown that these proalgesic factors are counteracted by a distinct group of lipid molecules that lower nociceptor excitability and attenuate nociception in peripheral ... ... hiện toàn bộ
Journal of Neuroscience - Tập 34 Số 46 - Trang 15184-15191 - 2014
Pavlovian Fear Conditioning Regulates Thr286Autophosphorylation of Ca2+/Calmodulin-Dependent Protein Kinase II at Lateral Amygdala SynapsesCa2 +/calmodulin-dependent protein kinase II (CaMKII) plays a critical role in synaptic plasticity and memory formation in a variety of learning systems and species. The present experiments examined the role of CaMKII in the circuitry underlying pavlovian fear conditioning. First, we reveal by immunocytochemical and tract-tracing methods that αCaMKII is postsynaptic to ... ... hiện toàn bộ
Journal of Neuroscience - Tập 24 Số 13 - Trang 3281-3288 - 2004
Dopaminergic innervation of A II amacrine cells in mammalian retinaDopaminergic amacrine cells were stained in cat, rat, and rabbit retina using an antibody against tyrosine hydroxylase (TH). Following intraocular injection of DAPI (4,6,diamidino-2-phenylindole), subsequent retinal whole-mount preparations revealed that the dopaminergic fiber plexus formed rings around amacrine cell bodies. Intracellular injection of Lucifer yellow (LY) into A II amacrine... ... hiện toàn bộ
Journal of Neuroscience - Tập 7 Số 12 - Trang 4115-4128 - 1987
Elevated expression of type II Na+ channels in hypomyelinated axons of shiverer mouse brainType I and type III Na+ channels are localized mainly in neuronal cell bodies in mouse brain. Type II channels are preferentially localized in unmyelinated fiber tracts but are not detectable in normally myelinated fibers. In shiverer mice, which lack compact myelin due to a defect in the myelin basic protein gene, elevated expression of type II Na+ channels was observed in the hypomyelina... ... hiện toàn bộ
Journal of Neuroscience - Tập 12 Số 6 - Trang 2259-2267 - 1992
Potentiation of L-Type Calcium Channels Reveals Nonsynaptic Mechanisms that Correlate Spontaneous Activity in the Developing Mammalian Retina
Journal of Neuroscience - Tập 21 Số 21 - Trang 8514-8522 - 2001
Mechanisms of Lateral Inhibition in the Olfactory Bulb: Efficiency and Modulation of Spike-Evoked Calcium Influx into Granule CellsGranule cells are axonless local interneurons that mediate lateral inhibitory interactions between the principal neurons of the olfactory bulb via dendrodendritic reciprocal synapses. This unusual arrangement may give rise to functional properties different from conventional lateral inhibition. Although granule cells spike, little is known about the role of the action potential with respec... ... hiện toàn bộ
Journal of Neuroscience - Tập 23 Số 20 - Trang 7551-7558 - 2003
Propagating Neocortical Gamma Bursts Are Coordinated by Traveling Alpha WavesNeocortical neuronal activity is characterized by complex spatiotemporal dynamics. Although slow oscillations have been shown to travel over space in terms of consistent phase advances, it is unknown how this phenomenon relates to neuronal activity in other frequency bands. We here present electrocorticographic data from three male and one female human subject and demonstrate that gamma po... ... hiện toàn bộ
Journal of Neuroscience - Tập 33 Số 48 - Trang 18849-18854 - 2013
An NF-κB-Like Transcription Factor in Axoplasm is Rapidly Inactivated after Nerve Injury inAplysiaWe found a protein in Aplysia neurons that has many characteristics of the transcription factor NF-κB. Thus, the protein recognized a radiolabeled probe containing the κB sequence from the human interferon-β gene enhancer element (PRDII), and the binding was not affected by PRDIV, an ATF-2 enhancer sequence from the same gene. Binding was efficiently inhibited, however, by nonradioactive o... ... hiện toàn bộ
Journal of Neuroscience - Tập 17 Số 13 - Trang 4915-4920 - 1997
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