Journal of Neurophysiology
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Receptive Properties of Mouse Sensory Neurons Innervating Hairy SkinKoltzenburg, Martin, Cheryl L. Stucky, and Gary R. Lewin. Receptive properties of mouse sensory neurons innervating hairy skin. J. Neurophysiol. 78: 1841–1850, 1997. Using an in vitro nerve skin preparation and controlled mechanical or thermal stimuli, we analyzed the receptive properties of 277 mechanosensitive single primary afferents with myelinated ( n = 251) or unmyelinated ( n = 26) ... ...
Journal of Neurophysiology - Tập 78 Số 4 - Trang 1841-1850 - 1997
Picrotoxin-induced epileptiform activity in hippocampus: role of endogenous versus synaptic factors Picrotoxin-(PTX) induced epileptiform activity was studied in guinea pig hippocampal slices maintained in vitro, using intra- and extracellular recording techniques. The observed pattern of spontaneous and evoked epileptiform activity was quite complex. Spontaneous epileptiform events originated in the CA3 region and subsequently spread or propagated to CA1. Activation of CA1 could then r... ...
Journal of Neurophysiology - Tập 51 Số 5 - Trang 1011-1027 - 1984
Auditory-Somatosensory Multisensory Processing in Auditory Association Cortex: An fMRI Study Using high-field (3 Tesla) functional magnetic resonance imaging (fMRI), we demonstrate that auditory and somatosensory inputs converge in a subregion of human auditory cortex along the superior temporal gyrus. Further, simultaneous stimulation in both sensory modalities resulted in activity exceeding that predicted by summing the responses to the unisensory inputs, thereby showing multis... ...
Journal of Neurophysiology - Tập 88 Số 1 - Trang 540-543 - 2002
Dynamic Model of the Octopus Arm. II. Control of Reaching MovementsThe dynamic model of the octopus arm described in the first paper of this 2-part series was used here to investigate the neural strategies used for controlling the reaching movements of the octopus arm. These are stereotypical extension movements used to reach toward an object. In the dynamic model, sending a simple propagating neural activation signal to contract all muscles along the arm... ...
Journal of Neurophysiology - Tập 94 Số 2 - Trang 1459-1468 - 2005
Mammalian voltage-activated calcium channel currents are blocked by Pb2+, Zn2+, and Al3+ 1. The effects of the di- and trivalent trace metal cations, Pb2+, Zn2+, and Al3+, on voltage-activated calcium channel currents recorded from cultured rat dorsal root ganglion neurons were determined. 2. All three cations blocked transient and sustained components of the voltage-gated calcium channel currents elicited by a voltage jump from -80 mV to 0 mV, but the trace metals differed i... ...
Journal of Neurophysiology - Tập 71 Số 4 - Trang 1491-1497 - 1994
Increased excitation-inhibition balance and loss of GABAergic synapses in the serine racemase knockout model of NMDA receptor hypofunction Recently, disruption of excitation/inhibition (E/I) balance has become an area of considerable interest for psychiatric research. Here, we report a reduction in inhibition in the serine racemase KO mouse model of schizophrenia that increases E/I balance and enhances synaptically driven neuronal excitability. This reduced inhibition was driven cell-autonomously in pyramidal cells lacking s... ...
Journal of Neurophysiology - Tập 126 Số 1 - Trang 11-27 - 2021
Chemosensitivity of fine afferents from rat skin in vitro 1. Properties of sensory receptors with slowly conducting nerve fibers (less than 10 m/s) were studied using a rat skin-saphenous nerve in vitro preparation where receptive fields of identified single units can be isolated and superfused at the corium side with defined chemical solutions. 2. With mechanical search stimuli, 150 slowly adapting units were identified, 88% C-fibers, and the r... ...
Journal of Neurophysiology - Tập 63 Số 4 - Trang 887-901 - 1990
Energy-related optimal control accounts for gravitational load: comparing shoulder, elbow, and wrist rotations We permanently deal with gravity force. Experimental evidences revealed that moving against gravity strongly differs from moving along the gravity vector. This directional asymmetry has been attributed to an optimal planning process that optimizes gravity force effects to minimize energy. Yet, only few studies have considered the case of vertical movements in the context of optimal contro... ...
Journal of Neurophysiology - Tập 111 Số 1 - Trang 4-16 - 2014
Interjoint dynamic interaction during constrained human quiet standing examined by induced acceleration analysis Recent studies have demonstrated that human quiet standing is a multijoint movement, whereby the central nervous system (CNS) is required to deal with dynamic interactions among the joints to achieve optimal motor performance. The purpose of this study was to investigate how the CNS deals with such interjoint interaction during quiet standing by examining the relationship between the kine... ...
Journal of Neurophysiology - Tập 111 Số 2 - Trang 313-322 - 2014
Optimal Integration of Gravity in Trajectory Planning of Vertical Pointing Movements The planning and control of motor actions requires knowledge of the dynamics of the controlled limb to generate the appropriate muscular commands and achieve the desired goal. Such planning and control imply that the CNS must be able to deal with forces and constraints acting on the limb, such as the omnipresent force of gravity. The present study investigates the effect of hypergravity i... ...
Journal of Neurophysiology - Tập 102 Số 2 - Trang 786-796 - 2009
Tổng số: 760
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