Journal of Neurochemistry

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Role of oxidative stress in paraquat‐induced dopaminergic cell degeneration
Journal of Neurochemistry - Tập 93 Số 4 - Trang 1030-1037 - 2005
Alison L. McCormack, Jennifer G Atienza, Louisa C. Johnston, Julie K. Andersen, Susan Vu, Donato A. Di Monte
AbstractSystemic treatment of mice with the herbicide paraquat causes the selective loss of nigrostriatal dopaminergic neurons, reproducing the primary neurodegenerative feature of Parkinson's disease. To elucidate the role of oxidative damage in paraquat neurotoxicity, the time‐course of neurodegeneration was correlated to changes in 4‐hydroxy‐2‐nonenal (4‐HNE), a lipid peroxidation marker. When ... hiện toàn bộ
Molecular Cloning and Regional Distribution of a Human Proton Receptor Subunit with Biphasic Functional Properties
Journal of Neurochemistry - Tập 72 Số 1 - Trang 51-57 - 1999
K. Babinski, Khanh-Tuoc Lê, Philippe Séguéla
Abstract : Small changes of extracellular pH activate depolarizing inward currents in most nociceptive neurons. It has been recently proposed that acid sensitivity of sensory as well as central neurons is mediated by a family of proton‐gated cation channels structurally related to Caenorhabditis elegans degenerins and mammalian epithelial sodium channels. We describe here the molecular cloning of ... hiện toàn bộ
DÉCARBOXYLASE GLUTAMIQUE ET HYDRAZONES DE PHOSPHO‐5‐PYRIDOXAL
Journal of Neurochemistry - Tập 9 Số 2 - Trang 135-142 - 1962
P Gonnard, S Fénard
RELATIONSHIPS AMONG PYRIDOXAL PHOSPHATE, VITAMIN B6‐DEFICIENCY, AND CONVULSIONS INDUCED BY 1,1‐DIMETHYLHYDRAZINE
Journal of Neurochemistry - Tập 14 Số 6 - Trang 681-692 - 1967
Frederick N. Minard
NEUROPHYSIOLOGICAL AND NEUROCHEMICAL STUDIES WITH THE ISONICOTINOYLHYDRAZONE OF PYRIDOXAL 5‐PHOSPHATE*
Journal of Neurochemistry - Tập 11 Số 11 - Trang 787-792 - 1964
V. Bonavita, Rosa Guarneri, Pietro Monaco
ENZYMIC FORMATION OF GAMMA‐AMINOBUTYRIC ACID IN THE PERIPHERAL AND CENTRAL NERVOUS SYSTEM OF LOBSTERS
Journal of Neurochemistry - Tập 9 Số 4 - Trang 363-370 - 1962
Edward A. Kravitz
A COMPARATIVE STUDY OF HYPERBARIC OXYGENINDUCED AND DRUG‐INDUCED CONVULSIONS WITH PARTICULAR REFERENCE TO γ‐AMINOBUTYRIC ACID METABOLISM*
Journal of Neurochemistry - Tập 13 Số 5 - Trang 361-370 - 1966
J. D. Wood, William J. Watson, N. E. Stacey
ACTION DE LA CYANACETYLHYDRAZONE DE PHOSPHO‐5′‐PYRIDOXAL SUR LA GLUTAMATE DECARBOXYLASE CEREBRALE. MODIFICATION DU TRACE ELECTROCORTICO‐GRAPHIQUE DU RAT. ACTION OF CYANACETYLHYDRAZONE OF PHOSPHO‐5′‐PYRIDOXAL ON THE CEREBRAL GLUTAMATE DECARBOXYLASE. MODIFICATION OF LECTROCORTICOGRAPHIC RECORD IN THE RAT
Journal of Neurochemistry - Tập 13 Số 5 - Trang 407-412 - 1966
P Gonnard, J Duhault
Presynaptic Adenosine A2 and N‐Methyl‐D‐Aspartate Receptors Regulate Dopamine Synthesis in Rat Striatal Synaptosomes
Journal of Neurochemistry - Tập 56 Số 5 - Trang 1783-1788 - 1991
Muhammad Abdul Baker Chowdhury, Marianne Fillenz
Abstract: Dopamine synthesis rate and cyclic AMP concentration were measured in synaptosomes prepared from rat striatum. Dopamine synthesis rate was decreased by the addition of either adenosine deaminase or 8‐phenyltheophylline, an adenosine receptor blocker, and was increased by the addition of 2‐chloroadenosine. The addition of L‐glutamate in the absence of adenosine deaminase decreased both do... hiện toàn bộ
Tissue Distribution of Human Monoamine Oxidase A and B mRNA
Journal of Neurochemistry - Tập 55 Số 4 - Trang 1166-1169 - 1990
Joseph Grimsby, Nancy C. Lan, Rachael L. Neve, Kevin Chen, Jean C. Shih
Abstract: Monoamine oxidase (MAO) A and B play important roles in the metabolism of biogenic amines. Northern analysis using 32P‐labeled subfragments of human liver MAO A and B cDNA clones detected a 5‐ and a 3‐kb transcript, respectively, in most human tissues examined. However, fetal heart and thymus express minute amounts of MAO A transcript, whereas fetal brain, muscle, thymus, spleen, meninge... hiện toàn bộ
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