Journal of Neurochemistry
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Sắp xếp:
Role of oxidative stress in paraquat‐induced dopaminergic cell degeneration
Journal of Neurochemistry - Tập 93 Số 4 - Trang 1030-1037 - 2005
AbstractSystemic treatment of mice with the herbicide paraquat causes the
selective loss of nigrostriatal dopaminergic neurons, reproducing the primary
neurodegenerative feature of Parkinson's disease. To elucidate the role of
oxidative damage in paraquat neurotoxicity, the time‐course of neurodegeneration
was correlated to changes in 4‐hydroxy‐2‐nonenal (4‐HNE), a lipid peroxidation
marker. When ...
Functional Characterization of the Murine Serotonin Transporter Gene Promoter in Serotonergic Raphe Neurons
Journal of Neurochemistry - Tập 70 Số 3 - Trang 932-939 - 1998
Abstract: We have isolated and characterized the 5′‐flanking regulatory region
of the murine serotonin 5‐HT transporter (5‐HTT) gene. A TATA‐like motif and
several potential binding sites for transcription factors, including two AP1,
several AP2 and AP4 binding sites, CCAAT and GC boxes (SP1 binding sites), a
nuclear factor‐κB, and a cyclic AMP response element‐like motif, are present in
the 5′‐fl...
Molecular Cloning and Regional Distribution of a Human Proton Receptor Subunit with Biphasic Functional Properties
Journal of Neurochemistry - Tập 72 Số 1 - Trang 51-57 - 1999
Abstract : Small changes of extracellular pH activate depolarizing inward
currents in most nociceptive neurons. It has been recently proposed that acid
sensitivity of sensory as well as central neurons is mediated by a family of
proton‐gated cation channels structurally related to Caenorhabditis elegans
degenerins and mammalian epithelial sodium channels. We describe here the
molecular cloning of ...
DÉCARBOXYLASE GLUTAMIQUE ET HYDRAZONES DE PHOSPHO‐5‐PYRIDOXAL
Journal of Neurochemistry - Tập 9 Số 2 - Trang 135-142 - 1962
RELATIONSHIPS AMONG PYRIDOXAL PHOSPHATE, VITAMIN B6‐DEFICIENCY, AND CONVULSIONS INDUCED BY 1,1‐DIMETHYLHYDRAZINE
Journal of Neurochemistry - Tập 14 Số 6 - Trang 681-692 - 1967
NEUROPHYSIOLOGICAL AND NEUROCHEMICAL STUDIES WITH THE ISONICOTINOYLHYDRAZONE OF PYRIDOXAL 5‐PHOSPHATE*
Journal of Neurochemistry - Tập 11 Số 11 - Trang 787-792 - 1964
ENZYMIC FORMATION OF GAMMA‐AMINOBUTYRIC ACID IN THE PERIPHERAL AND CENTRAL NERVOUS SYSTEM OF LOBSTERS
Journal of Neurochemistry - Tập 9 Số 4 - Trang 363-370 - 1962
A COMPARATIVE STUDY OF HYPERBARIC OXYGENINDUCED AND DRUG‐INDUCED CONVULSIONS WITH PARTICULAR REFERENCE TO γ‐AMINOBUTYRIC ACID METABOLISM*
Journal of Neurochemistry - Tập 13 Số 5 - Trang 361-370 - 1966
ACTION DE LA CYANACETYLHYDRAZONE DE PHOSPHO‐5′‐PYRIDOXAL SUR LA GLUTAMATE DECARBOXYLASE CEREBRALE. MODIFICATION DU TRACE ELECTROCORTICO‐GRAPHIQUE DU RAT. ACTION OF CYANACETYLHYDRAZONE OF PHOSPHO‐5′‐PYRIDOXAL ON THE CEREBRAL GLUTAMATE DECARBOXYLASE. MODIFICATION OF LECTROCORTICOGRAPHIC RECORD IN THE RAT
Journal of Neurochemistry - Tập 13 Số 5 - Trang 407-412 - 1966
Ammonia Intoxication: Effects on Cerebral Cortex and Spinal Cord
Journal of Neurochemistry - Tập 44 Số 4 - Trang 1252-1258 - 1985
Abstract: The effect of an acute systemic ammonia intoxication on the metabolic
states of the cerebral cortex and the spinal cord of the same animal was studied
in the cat. The intravenous infusion of ammonium acetate (2 and 4 mmol/kg body
weight/30 min) increased the gross levels of tissue NH4, glutamine,
glutamine/glutamate ratio, lactate, and the lactate/pyruvate ratio in the
cerebral cortex an...
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