Journal of Nanobiotechnology
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Silver nanoparticles of Albizia adianthifolia: the induction of apoptosis in human lung carcinoma cell lineAbstract Background Silver nanoparticles (AgNP), the most popular nano-compounds, possess unique properties.Albizia adianthifolia (AA) is a plant of the Fabaceae family that is rich in saponins. The biological properties of a novel AgNP, synthesized from an aqueous leaf extract of AA (AAAgNP... hiện toàn bộ
Journal of Nanobiotechnology - Tập 11 Số 1 - 2013
Hyaluronic acid-FGF2-derived peptide bioconjugates for suppression of FGFR2 and AR simultaneously as an acne antagonistAbstract Acne is a chronic skin condition that has serious consequences for mental and social well-being because it frequently occurs on the face. Several acne treatment approaches have commonly been used but have been hampered by side effects or weak activity. Thus, the investigation of the safety and efficacy of anti-acne compounds is of considerable medical impor... ... hiện toàn bộ
Journal of Nanobiotechnology -
Nanomechanical properties of enucleated cells: contribution of the nucleus to the passive cell mechanicsAbstract
Background
The nucleus, besides its functions in the gene maintenance and regulation, plays a significant role in the cell mechanosensitivity and mechanotransduction. It is the largest cellular organelle that is often considered as the stiffest cell part as well. Interestingly, the previous... ... hiện toàn bộ
Journal of Nanobiotechnology - - 2020
Nanomaterial enabled sensors for environmental contaminants
Journal of Nanobiotechnology - Tập 16 - Trang 1-16 - 2018
The need and desire to understand the environment, especially the quality of one’s local water and air, has continued to expand with the emergence of the digital age. The bottleneck in understanding the environment has switched from being able to store all of the data collected to collecting enough data on a broad range of contaminants of environmental concern. Nanomaterial enabled sensors represe...... hiện toàn bộ
A thermoreversible antibacterial zeolite-based nanoparticles loaded hydrogel promotes diabetic wound healing via detrimental factor neutralization and ROS scavenging
Journal of Nanobiotechnology - Tập 19 - Trang 1-20 - 2021
As recovery time of diabetic wound injury is prolonged by the production of detrimental factors, including reactive oxygen species (ROS) and inflammatory cytokines, attenuating the oxidative stress and inflammatory reactions in the microenvironment of the diabetic wound site would be significant. In our study, we prepared thermoreversible, antibacterial zeolite-based nanoparticles loaded hydrogel ...... hiện toàn bộ
Development of multivalent nanobodies blocking SARS-CoV-2 infection by targeting RBD of spike protein
Journal of Nanobiotechnology - Tập 19 - Trang 1-12 - 2021
The outbreak and pandemic of coronavirus SARS-CoV-2 caused significant threaten to global public health and economic consequences. It is extremely urgent that global people must take actions to develop safe and effective preventions and therapeutics. Nanobodies, which are derived from single‑chain camelid antibodies, had shown antiviral properties in various challenge viruses. In this study, multi...... hiện toàn bộ
Bioengineered stem cell membrane functionalized nanoparticles combine anti-inflammatory and antimicrobial properties for sepsis treatment
Journal of Nanobiotechnology - Tập 21 - Trang 1-19 - 2023
Sepsis is a syndrome of physiological, pathological and biochemical abnormalities caused by infection. Although the mortality rate is lower than before, many survivors have persistent infection, which means sepsis calls for new treatment. After infection, inflammatory mediators were largely released into the blood, leading to multiple organ dysfunction. Therefore, anti-infection and anti-inflammat...... hiện toàn bộ
Hypoxia-responsive nanoreactors based on self-enhanced photodynamic sensitization and triggered ferroptosis for cancer synergistic therapy
Journal of Nanobiotechnology - Tập 19 - Trang 1-14 - 2021
Photodynamic therapy (PDT), a typical reactive oxygen species (ROS)-dependent treatment with high controllability, has emerged as an alternative cancer therapy modality but its therapeutic efficacy is still unsatisfactory due to the limited light penetration and constant oxygen consumption. With the development of another ROS-dependent paradigm ferroptosis, several efforts have been made to conque...... hiện toàn bộ
Antioxidant capacities of the selenium nanoparticles stabilized by chitosan
Journal of Nanobiotechnology - Tập 15 - Trang 1-12 - 2017
Selenium (Se) as one of the essential trace elements for human plays an important role in the oxidation reduction system. But the high toxicity of Se limits its application. In this case, the element Se with zero oxidation state (Se0) has captured our attention because of its low toxicity and excellent bioavailability. However, Se0 is very unstable and easily changes into the inactive form. By now...... hiện toàn bộ
Emerging nanobiotechnology for precise theranostics of hepatocellular carcinoma
Journal of Nanobiotechnology - Tập 20 - Trang 1-21 - 2022
Primary liver cancer has become the second most fatal cancer in the world, and its five-year survival rate is only 10%. Most patients are in the middle and advanced stages at the time of diagnosis, losing the opportunity for radical treatment. Liver cancer is not sensitive to chemotherapy or radiotherapy. At present, conventional molecularly targeted drugs for liver cancer show some problems, such...... hiện toàn bộ
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