Journal of Mammary Gland Biology and Neoplasia

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Methicillin Resistant S. aureus in Human and Bovine Mastitis
Journal of Mammary Gland Biology and Neoplasia - Tập 16 - Trang 373-382 - 2011
Mark A. Holmes, Ruth N. Zadoks
Staphylococcus aureus is a ubiquitous organism that causes a variety of diseases including mastitis in cattle and humans. High-level resistance of S. aureus to β-lactams conferred by a mecA gene encoding a modified penicillin binding protein (PBP2a) was first observed in the early 1960’s. These methicillin resistant S. aureus (MRSA) have been responsible for both hospital ...... hiện toàn bộ
The National Mastitis Council: A Global Organization for Mastitis Control and Milk Quality, 50 Years and Beyond
Journal of Mammary Gland Biology and Neoplasia - - 2014
John R. Middleton, A.I. Saeman, L.K. Fox, Jason E. Lombard, J.S. Hogan, Kenneth L. Smith
Insulin and IGFs in Obesity-Related Breast Cancer
Journal of Mammary Gland Biology and Neoplasia - Tập 18 - Trang 277-289 - 2013
Valentina Belardi, Emily J. Gallagher, Ruslan Novosyadlyy, Derek LeRoith
Obesity and the Metabolic Syndrome are associated with multiple factors that may cause an increased risk for cancer and cancer-related mortality. Factors involved include hyperinsulinemia, hyperglycemia, hyperlipidemia and IGFs. Insulin resistance is also associated with alterations in the levels of proinflammatory cytokines, chemokines, adipokines (leptin, adiponectin) that may also be contributi...... hiện toàn bộ
Dissecting Tissue-Specific Super-Enhancers by Integrating Genome-Wide Analyses and CRISPR/Cas9 Genome Editing
Journal of Mammary Gland Biology and Neoplasia - Tập 24 - Trang 47-59 - 2018
Kyung Hyun Yoo, Lothar Hennighausen, Ha Youn Shin
Recent advances in genome-wide sequencing technologies have provided researchers with unprecedented opportunities to discover the genomic structures of gene regulatory units in living organisms. In particular, the integration of ChIP-seq, RNA-seq, and DNase-seq techniques has facilitated the mapping of a new class of regulatory elements. These elements, called super-enhancers, can regulate cell-ty...... hiện toàn bộ
A Detailed Mammosphere Assay Protocol for the Quantification of Breast Stem Cell Activity
Journal of Mammary Gland Biology and Neoplasia - - 2012
Frances L. Shaw, Hannah Harrison, Katherine Spence, Matthew P. Ablett, Bruno M. Simões, Gillian Farnie, Robert B. Clarke
Since the discovery that neural tissue contains a population of stem cells that form neurospheres in vitro, sphere-forming assays have been adapted for use with a number of different tissue types for the quantification of stem cell activity and self-renewal. One tissue type widely used for stem cell investigations is mammary tissue, and the mammosphere assay has been used in both normal tissue and...... hiện toàn bộ
New Insights on COX-2 in Chronic Inflammation Driving Breast Cancer Growth and Metastasis
Journal of Mammary Gland Biology and Neoplasia - Tập 20 - Trang 109-119 - 2015
Honor J. Hugo, C. Saunders, R. G. Ramsay, E. W. Thompson
The medicinal use of aspirin stretches back to ancient times, before it was manufactured in its pure form in the late 19th century. Its accepted mechanistic target, cyclooxygenase (COX), was discovered in the 1970s and since this landmark discovery, the therapeutic application of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) has increased dramatically. The most significant benef...... hiện toàn bộ
MTA Family of Transcriptional Metaregulators in Mammary Gland Morphogenesis and Breast Cancer
Journal of Mammary Gland Biology and Neoplasia - - 2007
Rajesh R. Singh, Rakesh Kumar
Nutrition and Human Lactation
Journal of Mammary Gland Biology and Neoplasia - Tập 4 - Trang 241-242 - 1999
Kathryn G. Dewey, Richard J. Schanler, Berthold Koletzko
Longitudinal analysis of bovine mammary gland development
Journal of Mammary Gland Biology and Neoplasia - Tập 28 - Trang 1-11 - 2023
Alysia L. Vang, Tiago Bresolin, Waneska S. Frizzarini, Guilherme L. Menezes, Thiago Cunha, Guilherme J. M. Rosa, Laura L. Hernandez, Joao R. R. Dorea
Many studies on bovine mammary glands focus on one stage of development. Often missing in those studies are repeated measures of development from the same animals. As milk production is directly affected by amount of parenchymal tissue within the udder, understanding mammary gland growth along with visualization of its structures during development is essential. Therefore, analysis of ultrasound a...... hiện toàn bộ
Estrous Cycle Regulation of Mammary Epithelial Cell Proliferation, Differentiation, and Death in the Sprague-Dawley Rat: A Model for Investigating the Role of Estrous Cycling in Mammary Carcinogenesis
Journal of Mammary Gland Biology and Neoplasia - Tập 5 - Trang 211-225 - 2000
P. Schedin, T. Mitrenga, M. Kaeck
The Sprague-Dawley rat is highly regarded for studies designed to investigate the effects of endocrine modulation on mammary carcinogenesis. In this study, we further evaluate the validity of the Sprague-Dawley rat model for the study of human breast cancer by evaluating the effects of normal 4-day estrous cycling on mammary epithelial cell proliferation, differentiation, and apoptotic death. Tren...... hiện toàn bộ
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