Journal of General Physiology

SCOPUS (1919,1930,1933,1936,1945-2023)SCIE-ISI

  0022-1295

  1540-7748

  Mỹ

Cơ quản chủ quản:  ROCKEFELLER UNIV PRESS , Rockefeller University Press

Lĩnh vực:
Physiology

Các bài báo tiêu biểu

THE METABOLISM OF TUMORS IN THE BODY
Tập 8 Số 6 - Trang 519-530 - 1927
Otto Warbürg, Franz Wind, Erwin Negelein
THE ESTIMATION OF PEPSIN, TRYPSIN, PAPAIN, AND CATHEPSIN WITH HEMOGLOBIN
Tập 22 Số 1 - Trang 79-89 - 1938
M. L. Anson
POTENTIAL, IMPEDANCE, AND RECTIFICATION IN MEMBRANES
Tập 27 Số 1 - Trang 37-60 - 1943
David E. Goldman
Impedance and potential measurements have been made on a number of artificial membranes. Impedance changes were determined as functions of current and of the composition of the environmental solutions. It was shown that rectification is present in asymmetrical systems and that it increases with the membrane potential. The behavior in pairs of solutions of the same salt at different concent...... hiện toàn bộ
Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction.
Tập 69 Số 4 - Trang 497-515 - 1977
Bertil Hille
The properties of Na channels of the node of Ranvier are altered by neutral, amine, and quaternary local anesthetic compounds. The kinetics of the Na currents are governed by a composite of voltage- and time-dependent gating processes with voltage- and time-dependent block of channels by drug. Conventional measurements of steady-state sodium inactivation by use of 50-ms prepulses show a la...... hiện toàn bộ
INDEPENDENT FUNCTIONS OF VIRAL PROTEIN AND NUCLEIC ACID IN GROWTH OF BACTERIOPHAGE
Tập 36 Số 1 - Trang 39-56 - 1952
A. D. Hershey, Martha Chase
1. Osmotic shock disrupts particles of phage T2 into material containing nearly all the phage sulfur in a form precipitable by antiphage serum, and capable of specific adsorption to bacteria. It releases into solution nearly all the phage DNA in a form not precipitable by antiserum and not adsorbable to bacteria. The sulfur-containing protein of the phage particle evidently makes up a memb...... hiện toàn bộ
Interaction of Tetraethylammonium Ion Derivatives with the Potassium Channels of Giant Axons
Tập 58 Số 4 - Trang 413-437 - 1971
Clay M. Armstrong
A number of compounds related to TEA+ (tetraethylammoniumion) were injected into squid axons and their effects on gK (the potassium conductance) were determined. In most of these ions a quaternary nitrogen is surrounded by three ethyl groups and a fourth group that is very hydrophobic. Several of the ions cause inactivation of gK, a type of ionic gating that is not normally seen in squid a...... hiện toàn bộ
Time and calcium dependence of activation and inactivation of calcium-induced release of calcium from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell.
Tập 85 Số 2 - Trang 247-289 - 1985
A Fabiato
Microprocessor-controlled changes of [free Ca2+] at the outer surface of the sarcoplasmic reticulum (SR) wrapped around individual myofibrils of a skinned canine cardiac Purkinje cell and aequorin bioluminescence recording were used to study the mechanism of Ca2+-induced release of Ca2+ from the SR. This Ca2+ release is triggered by a rapid increase of [free Ca2+] at the outer surface of t...... hiện toàn bộ
Anatomy and Physiology of Vision in the Frog (Rana pipiens)
Tập 43 Số 6 - Trang 129-175 - 1960
Humberto R. Maturana, Jerome Y. Lettvin, Warren S. McCulloch, Walter Pitts
The Permeability of the Sodium Channel to Organic Cations in Myelinated Nerve
Tập 58 Số 6 - Trang 599-619 - 1971
Bertil Hille
The relative permeability of sodium channels to 21 organic cations was studied in myelinated nerve fibers. Ionic currents under voltage-clamp conditions were measured in sodium-free solutions containing the test cation. The measured reversal potential and the Goldman equation were used to calculate relative permeabilities. The permeability sequence was: sodium ≈ hydroxylamine > hydr...... hiện toàn bộ
A Physical Interpretation of the Phenomenological Coefficients of Membrane Permeability
Tập 45 Số 1 - Trang 143-179 - 1961
O. Kedem, A. Katchalsky
A "translation" of the phenomenological permeability coefficients into friction and distribution coefficients amenable to physical interpretation is presented. Expressions are obtained for the solute permeability coefficient ω and the reflection coefficient σ for both non-electrolytic and electrolytic permeants. An analysis of the coefficients is given for loose membranes as well as for de...... hiện toàn bộ