Reactive oxygen and mechanisms of inflammatory liver injury: Present concepts Tập 26 Số s1 - Trang 173-179 - 2011
Hartmut Jaeschke
AbstractLiver cell death induced by stresses such as ischemia‐reperfusion, cholestasis and drug toxicity can trigger a sterile inflammatory response with activation of innate immune cells through release of damage‐associated molecular patterns (DAMPs). A similar inflammatory response can be induced by pathogen‐associated molecular patterns (PAMPs) such as endotoxin...... hiện toàn bộ Epidemiological characteristics and risk factors of hepatocellular carcinoma Tập 12 Số 9-10 - 1997
Chien‐Jen Chen, Ming‐Whei Yu, Yun‐Fan Liaw
ABSTRACTHepatocellular carcinoma (HCC) is one of the major cancers in the world. There is a striking variation in HCC incidence rates between various countries, with a highest‐to‐lowest ratio of 112.5 for males and 54.7 for females. The high‐risk populations are clustered in sub‐Saharan Africa and eastern Asia. The male‐to‐female ratio for HCC ranges from < 1 to...... hiện toàn bộ The epidemiology of inflammatory bowel disease: East meets west Tập 35 Số 3 - Trang 380-389 - 2020
Joyce Wing Yan Mak, Mirabella Zhao, Siew C. Ng, Johan Burisch
AbstractThe incidence of inflammatory bowel diseases (IBD) in East has risen over the past decade to become a global disease. The increasing number of studies on the incidence and course of IBD in East has enabled us to explore East versus West differences in the epidemiology of IBD which could enhance our understanding of the heterogeneity of the disease and event...... hiện toàn bộ Non‐alcoholic steatohepatitis in type 2 diabetes mellitus Tập 19 Số 8 - Trang 854-858 - 2004
Parijat Gupte, Deepak Amarapurkar, Subhash Agal, Rajiv Baijal, PRAMOD KULSHRESTHA, SNEHANSU PRAMANIK, Hynek Pikhart, Aruna Madan, Anjali Amarapurkar, HAFEEZUNNISA
AbstractBackground and Aims: Non‐alcoholic steatohepatitis (NASH) is commonly associated with type 2 diabetes mellitus (DM). Prevalence of NASH in type 2 DM has not been well studied and there is an epidemic rise in type 2 DM in Asian and Western populations. Its association with chronic liver disease in the form of NASH makes it an importan...... hiện toàn bộ Role of hepatic stellate cells in fibrogenesis and the reversal of fibrosis Tập 22 Số s1 - 2007
Tatiana Kisseleva, David A. Brenner
AbstractLiver fibrosis is caused by many chronic diseases. Liver injury results in activation of collagen‐producing cells and excessive deposition of extracellular matrix proteins. This process is orchestrated by many cell types. Hepatocytes apoptosis and inflammatory cells trigger secretion of profibrogenic and proinflammatory cytokines, such as transforming growt...... hiện toàn bộ Rapid hepatic fate specification of adipose‐derived stem cells and their therapeutic potential for liver failure Tập 24 Số 1 - Trang 70-77 - 2009
Agnieszka Banaś-Za̧bczyk, Takumi Teratani, Yusuke Yamamoto, Makoto Tokuhara, Fumitaka Takeshita, Mitsuhiko Osaki, Takashi Kato, Hitoshi Okochi, Takahiro Ochiya
AbstractBackground and Aim: Multipotential mesenchymal stem cells (MSC), present in many organs and tissues, represent an attractive tool for the establishment of a successful stem cell‐based therapy in the field of regeneration medicine. Adipose tissue mesenchymal stem cells (AT‐MSC), known as adipose‐derived stem cells (ASC) are especially...... hiện toàn bộ What's new in liver fibrosis? The origin of myofibroblasts in liver fibrosis Tập 27 Số s2 - Trang 65-68 - 2012
Keiko Iwaisako, David A. Brenner, Tatiana Kisseleva
AbstractChronic liver injury of many etiologies produces liver fibrosis and may eventually lead to the formation of cirrhosis. Fibrosis is part of a dynamic process associated with the continuous deposition and resorption of extracellular matrix, mainly fibrillar collagen. Studies of fibrogenesis conducted in many organs including the liver demonstrate that the pri...... hiện toàn bộ